CERK cdna clone
CERK cDNA Clone
Gene Names
CERK; LK4; hCERK; dA59H18.2; dA59H18.3
Synonyms
CERK; CERK cDNA Clone; CERK cdna clone
Sequence
ATGGGGGCGACGGGGGCGGCGGAGCCGCTGCAATCCGTGCTGTGGGTGAAGCAGCAGCGCTGCGCCGTGAGCCTGGAGCCCGCGCGGGCTCTGCTGCGCTGGTGGCGGAGCCCGGGGCCCGGAGCCGGCGCCCCCGGCGCGGATGCCTGCTCTGTGCCTGTATCTGAGATCATCGCCGTTGAGGAAACAGACGTTCACGGGAAACATCAAGGCAGTGGAAAATGGCAGAAAATGGAAAAGCCTTACGCTTTTACAGTTCACTGTGTAAAGAGAGCACGACGGCACCGCTGGAAGTGGGCGCAGGTGACTTTCTGGTGTCCAGAGGAGCAGCTGTGTCACTTGTGGCTGCAGACCCTGCGGGAGATGCTGGAGAAGCTGACGTCCAGACCAAAGCATTTACTGGTATTTATCAACCCGTTTGGAGGAAAAGGACAAGGCAAGCGGATATATGAAAGAAAAGTGGCACCACTGTTCACCTTAGCCTCCATCACCACTGACATCATCGTTACTGAACATGCTAATCAGGCCAAGGAGACTCTGTATGAGATTAACATAGACAAATACGACGGCATCGTCTGTGTCGGCGGAGATGGTATGTTCAGCGAGGTGCTGCACGGTCTGATTGGGAGGACGCAGAGGAGCGCCGGGGTCGACCAGAACCACCCCCGGGCTGTGCTGGTCCCCAGTAGCCTCCGGATTGGAATCATTCCCGCAGGGTCAACGGACTGCGTGTGTTACTCCACCGTGGGCACCAGCGACGCAGAAACCTCGGCGCTGCATATCGTTGTTGGGGACTCGCTGGCCATGGATGTGTCCTCAGTCCACCACAACAGCACACTCCTTCGCTACTCCGTGTCCCTGCTGGGCTACGGCTTCTACGGGGACATCATCAAGGACAGTGAGAAGAAACGGTGGTTGGGTCTTGCCAGATACGACTTTTCAGGTTTAAAGACCTTCCTCTCCCACCACTGCTATGAAGGGACAGTGTCCTTCCTCCCTGCACAACACACGGTGGGATCTCCAAGGGATAGGAAGCCCTGCCGGGCAGGATGCTTTGTTTGCAGGCAAAGCAAGCAGCAGCTGGAGGAGGAGCAGAAGAAAGCACTGTATGGTTTGGAAGCTGCGGAGGACGTGGAGGAGTGGCAAGTCGTCTGTGGGAAGTTCCTGGCCATCAATGCCACAAACATGTCCTGTGCTTGTCGCCGGAGCCCCAGGGGCCTCTCCCCGGCTGCCCACTTGGGAGACGGGTCTTCTGACCTCATCCTCATCCGGAAATGCTCCAGGTTCAATTTTCTGAGATTTCTCATCAGGCACACCAACCAGCAGGACCAGTTTGACTTCACTTTTGTTGAAGTTTATCGCGTCAAGAAATTCCAGTTTACGTCGAAGCACATGGAGGATGAGGACAGCGACCTCAAGGAGGGGGGGAAGAAGCGCTTTGGGCACATTTGCAGCAGCCACCCCTCCTGCTGCTGCACCGTCTCCAACAGCTCCTGGAACTGCGACGGGGAGGTCCTGCACAGCCCTGCCATCGAGGTCAGAGTCCACTGCCAGCTGGTTCGACTCTTTGCACGAGGAATTGAAGAGAATCCGAAGCCAGACTCACACAGCTGA
Sequence Length
1614
Vector
Please Inquire
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
Molecular Weight
37,781 Da
NCBI Official Full Name
Homo sapiens ceramide kinase, mRNA
NCBI Official Synonym Full Names
ceramide kinase
NCBI Official Symbol
CERK
NCBI Official Synonym Symbols
LK4; hCERK; dA59H18.2; dA59H18.3
NCBI Protein Information
ceramide kinase
UniProt Protein Name
Ceramide kinase
Protein Family
UniProt Gene Name
CERK
UniProt Synonym Gene Names
KIAA1646; hCERK; LK4
UniProt Entry Name
CERK1_HUMAN
NCBI Description
CERK converts ceramide to ceramide 1-phosphate (C1P), a sphingolipid metabolite. Both CERK and C1P have been implicated in various cellular processes, including proliferation, apoptosis, phagocytosis, and inflammation (Kim et al., 2006 [PubMed 16488390]).[supplied by OMIM, Mar 2008]
Uniprot Description
CERK: Catalyzes specifically the phosphorylation of ceramide to form ceramide 1-phosphate. Acts efficiently on natural and analog ceramides (C6, C8, C16 ceramides, and C8-dihydroceramide), to a lesser extent on C2-ceramide and C6-dihydroceramide, but not on other lipids, such as various sphingosines. Binds phosphoinositides.
Protein type: Kinase, lipid; Lipid Metabolism - sphingolipid; EC 2.7.1.138
Chromosomal Location of Human Ortholog: 22q13.31
Cellular Component: integral to membrane; plasma membrane
Molecular Function: ceramide kinase activity; magnesium ion binding; protein binding
Biological Process: ceramide metabolic process; glycosphingolipid metabolic process
Research Articles on CERK
Similar Products
Product Notes
The CERK cerk (Catalog #AAA1272218) is a cDNA Clone and is intended for research purposes only. The product is available for immediate purchase. The amino acid sequence is listed below: ATGGGGGCGA CGGGGGCGGC GGAGCCGCTG CAATCCGTGC TGTGGGTGAA GCAGCAGCGC TGCGCCGTGA GCCTGGAGCC CGCGCGGGCT CTGCTGCGCT GGTGGCGGAG CCCGGGGCCC GGAGCCGGCG CCCCCGGCGC GGATGCCTGC TCTGTGCCTG TATCTGAGAT CATCGCCGTT GAGGAAACAG ACGTTCACGG GAAACATCAA GGCAGTGGAA AATGGCAGAA AATGGAAAAG CCTTACGCTT TTACAGTTCA CTGTGTAAAG AGAGCACGAC GGCACCGCTG GAAGTGGGCG CAGGTGACTT TCTGGTGTCC AGAGGAGCAG CTGTGTCACT TGTGGCTGCA GACCCTGCGG GAGATGCTGG AGAAGCTGAC GTCCAGACCA AAGCATTTAC TGGTATTTAT CAACCCGTTT GGAGGAAAAG GACAAGGCAA GCGGATATAT GAAAGAAAAG TGGCACCACT GTTCACCTTA GCCTCCATCA CCACTGACAT CATCGTTACT GAACATGCTA ATCAGGCCAA GGAGACTCTG TATGAGATTA ACATAGACAA ATACGACGGC ATCGTCTGTG TCGGCGGAGA TGGTATGTTC AGCGAGGTGC TGCACGGTCT GATTGGGAGG ACGCAGAGGA GCGCCGGGGT CGACCAGAAC CACCCCCGGG CTGTGCTGGT CCCCAGTAGC CTCCGGATTG GAATCATTCC CGCAGGGTCA ACGGACTGCG TGTGTTACTC CACCGTGGGC ACCAGCGACG CAGAAACCTC GGCGCTGCAT ATCGTTGTTG GGGACTCGCT GGCCATGGAT GTGTCCTCAG TCCACCACAA CAGCACACTC CTTCGCTACT CCGTGTCCCT GCTGGGCTAC GGCTTCTACG GGGACATCAT CAAGGACAGT GAGAAGAAAC GGTGGTTGGG TCTTGCCAGA TACGACTTTT CAGGTTTAAA GACCTTCCTC TCCCACCACT GCTATGAAGG GACAGTGTCC TTCCTCCCTG CACAACACAC GGTGGGATCT CCAAGGGATA GGAAGCCCTG CCGGGCAGGA TGCTTTGTTT GCAGGCAAAG CAAGCAGCAG CTGGAGGAGG AGCAGAAGAA AGCACTGTAT GGTTTGGAAG CTGCGGAGGA CGTGGAGGAG TGGCAAGTCG TCTGTGGGAA GTTCCTGGCC ATCAATGCCA CAAACATGTC CTGTGCTTGT CGCCGGAGCC CCAGGGGCCT CTCCCCGGCT GCCCACTTGG GAGACGGGTC TTCTGACCTC ATCCTCATCC GGAAATGCTC CAGGTTCAAT TTTCTGAGAT TTCTCATCAG GCACACCAAC CAGCAGGACC AGTTTGACTT CACTTTTGTT GAAGTTTATC GCGTCAAGAA ATTCCAGTTT ACGTCGAAGC ACATGGAGGA TGAGGACAGC GACCTCAAGG AGGGGGGGAA GAAGCGCTTT GGGCACATTT GCAGCAGCCA CCCCTCCTGC TGCTGCACCG TCTCCAACAG CTCCTGGAAC TGCGACGGGG AGGTCCTGCA CAGCCCTGCC ATCGAGGTCA GAGTCCACTG CCAGCTGGTT CGACTCTTTG CACGAGGAAT TGAAGAGAAT CCGAAGCCAG ACTCACACAG CTGA. It is sometimes possible for the material contained within the vial of "CERK, cDNA Clone" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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