Rabbit anti-Human SURF6 Polyclonal Antibody | anti-SURF6 antibody

SURF6, ID (SURF6, SURF-6, Surfeit locus protein 6) (Biotin)

Cat. Num. AAA6352678

• Gene Names: SURF6; RRP14
• Reactivity: Human
• Applications: Western Blot, ELISA
• Purity: Purified by Protein A Affinity Chromatography.
• Synonyms: SURF6; Polyclonal Antibody; ID (SURF6; SURF-6; Surfeit locus protein 6) (Biotin); Surfeit locus protein 6; anti-SURF6 antibody

• Host: Rabbit
• Reactivity: Human
• Clonality: Polyclonal
• Isotype: IgG
• Purity/Purification: Purified by Protein A Affinity Chromatography.
• Form/Format: Supplied as a liquid in PBS, pH 7.2. No preservative added. Labeled with Biotin.

• Applicable Applications for anti-SURF6 antibody: Western Blot (WB), ELISA (EIA)
• Application Notes: WB: 1:100-500; ELISA: 1:1,000; Applications are based on unconjugated antibody.
• Immunogen: SURF6 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 187-213 amino acids from the Central region of human SURF6.
• Conjugate: Biotin
• Note: Preservative Free
• Preparation and Storage: Store product at 4 degree C if to be used immediately within two weeks. For long-term storage, aliquot to avoid repeated freezing and thawing and store at -20 degree C. Aliquots are stable at -20 degree C for 12 months after receipt. Dilute required amount only prior to immediate use. Further dilutions can be made in assay buffer. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.

Western Blot (WB)

(SURF6 Antibody (Center) western blot analysis in A549 cell line lysates (35ug/lane).This demonstrates the SURF6 antibody detected the SURF6 protein (arrow).)

Related Product Information for anti-SURF6 antibody

This gene is located in the surfeit gene cluster, a group of very tightly linked genes that do not share sequence similarity. The gene demonstrates features of a housekeeping gene, being ubiquitously expressed, and the encoded protein has been localized to the nucleolus. The protein includes motifs found in both the mouse and fish orthologs, which suggests a putative function as a nucleolar-matrix protein with nucleic acid-binding properties, based on characteristics determined in mouse.

Product Categories/Family for anti-SURF6 antibody

Antibodies; Proteins

References

Polzikov, M., et al. Biochem. Biophys. Res. Commun. 327(1):143-149(2005). Andersen, J.S., et al. Nature 433(7021):77-83(2005). Angiolillo, A., et al. Gene 284 (1-2), 169-178 (2002): Andersen, J.S., et al. Curr. Biol. 12(1):1-11(2002). Magoulas, C., et al. Gene 243 (1-2), 115-123 (2000).

NCBI and Uniprot Product Information

• NCBI GI #: 19557702
• NCBI GeneID: 6838
• NCBI Accession #: NP_006744.2
• NCBI GenBank Nucleotide #: NM_006753.5
• UniProt Accession #: O75683; Q5T8U1; Q9BRK9; Q9BTZ5; Q9UK24
• Molecular Weight: 41,450 Da
• NCBI Official Full Name: surfeit locus protein 6 isoform 1
• NCBI Official Synonym Full Names: surfeit 6
• NCBI Official Symbol: SURF6
• NCBI Official Synonym Symbols: RRP14
• NCBI Protein Information: surfeit locus protein 6
• UniProt Protein Name: Surfeit locus protein 6
• Protein Family: Surfeit locus protein
• UniProt Gene Name: SURF6
• UniProt Synonym Gene Names: SURF-6

NCBI Description

This gene encodes a conserved protein that is localized to the nucleolus. The encoded protein may function as a nucleolar-matrix protein with nucleic acid-binding properties. There is a pseudogene for this gene on chromosome Y. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jul 2013]

Uniprot Description

Binds to both DNA and RNA in vitro, with a stronger binding capacity for RNA. May represent a nucleolar constitutive protein involved in ribosomal biosynthesis or assembly ().