RBM22 cdna clone
RBM22 cDNA Clone
NCBI and Uniprot Product Information
NCBI Description
This gene encodes an RNA binding protein. The encoded protein may play a role in cell division and may be involved in pre-mRNA splicing. Related pseudogenes exist on chromosomes 6, 7, 9, 13, 16, 18, and X. [provided by RefSeq, Mar 2009]
Uniprot Description
RBM22: Involved in the first step of pre-mRNA splicing. Binds directly to the internal stem-loop (ISL) domain of the U6 snRNA and to the pre-mRNA intron near the 5' splice site during the activation and catalytic phases of the spliceosome cycle. Involved in both translocations of the nuclear SLU7 to the cytoplasm and the cytosolic calcium-binding protein PDCD6 to the nucleus upon cellular stress responses. Belongs to the SLT11 family. 2 isoforms of the human protein are produced by alternative splicing.
Protein type: RNA splicing; RNA-binding; Spliceosome; RNA processing
Chromosomal Location of Human Ortholog: 5q33.1
Cellular Component: cytoplasm; nucleoplasm; nucleus
Molecular Function: calcium-dependent protein binding; nucleocytoplasmic transporter activity; protein binding; U6 snRNA binding
Biological Process: nuclear mRNA cis splicing, via U2-type spliceosome; nuclear mRNA splicing, via spliceosome; positive regulation of RNA splicing; protein import into nucleus, translocation; spliceosomal snRNP biogenesis
Research Articles on RBM22
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Product Notes
The RBM22 rbm22 (Catalog #AAA1271826) is a cDNA Clone and is intended for research purposes only. The product is available for immediate purchase. The amino acid sequence is listed below: atggcgacct ctctgggttc caacacctac aacaggcaga actgggagga tgcggacttc cccattctgt gccagacatg tcttggagaa aacccatata tccgaatgac caaagaaaag tatgggaagg aatgcaaaat ctgtgccagg ccattcacag tgtttcgctg gtgccctgga gtccgcatgc gtttcaagaa gactgaagtg tgccaaacct gcagtaaatt gaagaatgtc tgtcagacct gcctcttaga cctagagtat ggcctgccca tccaggttcg tgacgcagga ttgtctttta aagatgacat gccaaagtca gatgtcaaca aagagtacta tacacagaat atggagagag agatttctaa ctctgatgga acacggccag ttggcatgct ggggaaagcc acatctacca gtgacatgct gctcaaactg gcccggacca caccctacta caaaaggaat cgaccccaca tttgctcctt ctgggtgaaa ggagagtgta agagaggaga ggaatgtcca tacagacatg agaagcctac agatccagat gacccccttg ctgatcagaa tattaaagac cgttattacg gaatcaatga tcctgtagct gacaagcttc taaagcgggc ttcaacaatg cctcggctgg acccaccaga ggataaaact atcaccacac tatatgttgg tggtctaggt gataccatta ctgagacaga tttaagaaat catttctacc agttcggaga gatccggacg atcactgttg tgcagagaca gcagtgtgct ttcatccagt ttgccacacg gcaggctgca gaagtggctg ctgagaagtc ctttaataag ttgattgtaa atggccgcag actgaatgtg aaatggggaa gatcccaggc agccagagga aaagaaaaag agaaagatgg aactacagac tctgggatca aactagaacc tgttccagga ttgccaggag ctcttcctcc tcctcctgca gcagaagaag aagcctctgc caactacttc aacttgcccc caagtggtcc tccagctgtg gtgaacattg ctctgccacc gccccctggc attgctccac ccccaccccc aggttttggg ccacacatgt tccacccaat gggaccaccc cctcctttca tgcgggctcc aggaccaatc cactatcctt ctcaggaccc tcagaggatg ggagctcatg ctggaaaaca cagcagcccc tag. It is sometimes possible for the material contained within the vial of "RBM22, cDNA Clone" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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