EDC4 cdna clone
EDC4 cDNA Clone
Gene Names
EDC4; GE1; Ge-1; RCD8; HEDL5; HEDLS; RCD-8
Synonyms
EDC4; EDC4 cDNA Clone; EDC4 cdna clone
Sequence
atggcctcctgcgcgagcatcgacatcgaggacgccacgcagcacctgcgggacatcctcaagctggaccggcccgcgggcggccccagtgcagagagcccacggccatccagtgcctacaatggggacctcaatggacttctggtcccagacccgctctgctcaggtgatagtacctcagcaaacaagactggtcttcggaccatgccacccattaacctgcaagagaagcaggtcatctgtctctcaggagatgatagctccacctgcattgggattttggccaaggaggtggagattgtggctagcagtgactctagcatttcaagcaaggcccggggaagcaacaaggtgaaaattcagcctgtcgccaagtatgactgggaacagaagtactactatggcaacctgattgctgtgtctaactccttcttggcctatgccattcgggctgccaacaatggctctgccatggtgcgggtgatcagcgtcagcacttcggagcggaccttgctcaagggcttcacaggcagtgtggctgatctggctttcgcgcacctcaactctccacagctggcctgcctggatgaggcaggcaacctgttcgtgtggcgcttggctctggttaatggcaaaattcaagaagagatcttggtccatattcggcagccagagggcacgccactgaaccactttcgcaggatcatctggtgccccttcatccctgaggagagcgaagactgctgtgaggagagcagcccaacagtggccctgctgcatgaagaccgggctgaggtgtgggacctggacatgctccgctccagccacagtacctggcctgtggatgttagccagatcaagcagggcttcattgtggtaaaaggtcatagcacgtgcctcagtgaaggagccctctctcctgatgggactgtgctggctactgcgagccacgatggctatgtcaagttctggcagatctacattgaggggcaagatgagccaaggtgtctgcacgagtggaaacctcatgatgggcggcccctctcctgcctcctgttctgtgacaaccataagaaacaagaccctgatgtccctttctggaggttccttattactggtgctgaccagaaccgagagttaaagatgtggtgtacagtatcctggacctgcctgcagactattcgcttctccccagatatcttcagctcagtgagtgtgccccctagcctcaaggtttgcttggacctctcagcagaatacctgattctcagcgatgtgcaacggaaggtcctctatgtgatggagctgctgcaaaaccaggaggagggccacgcctgcttcagctccatctcggagttcctgctcacccaccctgtgctgagctttggtatccaggttgtgagtcgctgccggctacggcacactgaggtgctgcctgccgaagaggaaaatgacagcctgggtgctgatggtacccatggagccggtgccatggagtctgcggccggtgtgctcatcaagctcttttgtgtgcatactaaggcactgcaagatgtgcagatccgcttccagccacagctgaaccctgatgtggtggccccactgcccacccacactgcccacgaggacttcacatttggagagtctcggcccgaactgggctctgagggcctggggtcagccgctcacggctcccagcctgacctccgacgaatcgtggagctgcctgcacctgccgacttcctcagtctgagcagtgagaccaagcccaagttgatgacacctgacgccttcatgacacctagcgcctccttgcagcagatcactgcctctcccagcagcagcagcagcggtagcagcagcagcagcagcagtagcagcagctcccttacagctgtgtctgccatgagcagcacctcagctgtggacccctccttgaccaggccacctgaggagctgaccttgagccccaagctgcagctggatggcagcctgacaatgagcagcagtggcagccttcaggcaagcccgcgtggcctcctgcctggcctgctcccagccccagctgacaaactgactcccaaggggccgggccaggtgcctactgccacctctgcactgtccctggagctgcaggaagtggagcccctggggctaccccaagcctcccctagccgcactcgttcccctgatgtcatctcctcagcttccactgccctgtcccaggacatccctgagattgcatctgaggccctgtcccgtggttttggctcctctgcaccagagggccttgagccagacagtatggcttcagccgcctcggcactgcacctgctgtccccacggccccggccagggcccgagctcggcccccagctcgggcttgatggaggccctggggatggagatcggcataataccccctccctcctggaggcagccttgacccaggaggcctcgactcctgacagtcaggtttggcccacagcacctgacattactcgtgagacctgcagcaccctggcagaaagccccaggaatggccttcaggaaaagcacaagagcctggccttccaccgaccaccatatcacctgctgcagcaacgtgacagccaggatgccagtgctgagcaaagtgaccatgatgatgaggtggccagccttgcctctgcttcaggaggctttggcaccaaagttcctgctccacggctgcctgccaaggactggaagaccaagggatcccctcgaacctcacccaagctcaagaggaaaagcaagaaggatgatggggatgcagccatgggatcccggctcacagagcaccaggtggcagagccccctgaggactggccagcactaatttggcaacagcagagagagctggcagagctgcggcacagccaggaagagctgctgcagcgtctgtgtacccaactcgaaggcctgcagagcacagtcacaggccacgtagaacgtgcccttgagactcggcacgagcaggaacagcggcggctggagcgagcactggctgaggggcagcagcggggagggcagctgcaggagcagctgacacaacagttgtcccaagcactgtcgtcagctgtagctgggcggctagagcgcagcatacgggatgagatcaagaagacagtccctccatgtgtctcaaggagtctggagcctatggcaggccaactgagcaactcagtggctaccaagctcacagctgtggagggcagcatgaaagagaacatctccaagctgctcaagtccaagaacttgactgatgccatcgcccgagcagctgcagacacattacaagggccgatgcaggctgcctaccgggaagccttccagagtgtggtgctgccggcctttgagaagagctgccaggccatgttccagcaaatcaatgatagcttccggctggggacacaggaatacttgcagcagctagaaagccacatgaagagccggaaggcacgggaacaggaggccagggagcctgtgctagcccagctgcggggcctggtcagcacactgcagagtgccactgagcagatggcagccaccgtggccggcagtgttcgtgctgaggtgcagcaccagctgcatgtggctgtgggcagcctgcaggagtccattttagcacaggtacagcgcatcgttaagggtgaggtgagtgtggcgctcaaggagcagcaggccgccgtcacctccagcatcatgcaggccatgcgctcagctgctggcacacctgtcccctctgcccaccttgactgccaggcccagcaagcccatatcctgcagctgctgcagcagggccacctcaatcaggccttccagcaggcgctgacagctgctgacctgaacctggtgctgtatgtgtgtgaaactgtggacccagcccaggtttttgggcagccaccctgcccgctctcccagcctgtgctcctttccctcatccagcagctggcatctgaccttggcactcgaactgacctcaagctcagctacctggaagaggccgtgatgcacctggaccacagtgaccccatcactcgggaccacatgggctccgttatggcccaggtgcgccaaaagctttttcagttcctgcaggctgagccacacaactcacttggcaaagcagctcggcgtctcagcctcatgctgcatggcctcgtgacccccagcctcccttag
Sequence Length
4206
Vector
Please Inquire
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
Molecular Weight
109,728 Da
NCBI Official Full Name
Homo sapiens enhancer of mRNA decapping 4, mRNA
NCBI Official Synonym Full Names
enhancer of mRNA decapping 4
NCBI Official Symbol
EDC4
NCBI Official Synonym Symbols
GE1; Ge-1; RCD8; HEDL5; HEDLS; RCD-8
NCBI Protein Information
enhancer of mRNA-decapping protein 4
UniProt Protein Name
Enhancer of mRNA-decapping protein 4
Protein Family
UniProt Gene Name
EDC4
UniProt Synonym Gene Names
HEDLS; Hedls
UniProt Entry Name
EDC4_HUMAN
Uniprot Description
EDC4: a protein required for the 5' a?? 3' pathway of mRNA decapping and degradation-based post-transcriptional gene silencing. The proteins involved in 5' a?? 3' mRNA decay include DCP2, DCP1A, EDC3, EDC4 and DDX6, and are concentrated in cytoplasmic structures called mRNA "processing bodies" (P-bodies). Shortening of the 3'-poly(A) tail and removal of PABP precedes cleavage of the 5'-mRNA cap by a complex containing decapping enzymes 1A and 2 (DCP1A/DCP2). EDC4 enhances the catalytic activity of DCP2 in vitro. Shown to be required for silencing by miRNAs in Drosophila melanogaster. Two alternatively spliced human isoforms have been described.
Protein type: RNA processing
Chromosomal Location of Human Ortholog: 16q22.1
Cellular Component: cytoplasm; cytosol; intracellular membrane-bound organelle; membrane; nucleoplasm; nucleus
Molecular Function: protein binding
Research Articles on EDC4
Similar Products
Product Notes
The EDC4 edc4 (Catalog #AAA1271424) is a cDNA Clone and is intended for research purposes only. The product is available for immediate purchase. The amino acid sequence is listed below: atggcctcct gcgcgagcat cgacatcgag gacgccacgc agcacctgcg ggacatcctc aagctggacc ggcccgcggg cggccccagt gcagagagcc cacggccatc cagtgcctac aatggggacc tcaatggact tctggtccca gacccgctct gctcaggtga tagtacctca gcaaacaaga ctggtcttcg gaccatgcca cccattaacc tgcaagagaa gcaggtcatc tgtctctcag gagatgatag ctccacctgc attgggattt tggccaagga ggtggagatt gtggctagca gtgactctag catttcaagc aaggcccggg gaagcaacaa ggtgaaaatt cagcctgtcg ccaagtatga ctgggaacag aagtactact atggcaacct gattgctgtg tctaactcct tcttggccta tgccattcgg gctgccaaca atggctctgc catggtgcgg gtgatcagcg tcagcacttc ggagcggacc ttgctcaagg gcttcacagg cagtgtggct gatctggctt tcgcgcacct caactctcca cagctggcct gcctggatga ggcaggcaac ctgttcgtgt ggcgcttggc tctggttaat ggcaaaattc aagaagagat cttggtccat attcggcagc cagagggcac gccactgaac cactttcgca ggatcatctg gtgccccttc atccctgagg agagcgaaga ctgctgtgag gagagcagcc caacagtggc cctgctgcat gaagaccggg ctgaggtgtg ggacctggac atgctccgct ccagccacag tacctggcct gtggatgtta gccagatcaa gcagggcttc attgtggtaa aaggtcatag cacgtgcctc agtgaaggag ccctctctcc tgatgggact gtgctggcta ctgcgagcca cgatggctat gtcaagttct ggcagatcta cattgagggg caagatgagc caaggtgtct gcacgagtgg aaacctcatg atgggcggcc cctctcctgc ctcctgttct gtgacaacca taagaaacaa gaccctgatg tccctttctg gaggttcctt attactggtg ctgaccagaa ccgagagtta aagatgtggt gtacagtatc ctggacctgc ctgcagacta ttcgcttctc cccagatatc ttcagctcag tgagtgtgcc ccctagcctc aaggtttgct tggacctctc agcagaatac ctgattctca gcgatgtgca acggaaggtc ctctatgtga tggagctgct gcaaaaccag gaggagggcc acgcctgctt cagctccatc tcggagttcc tgctcaccca ccctgtgctg agctttggta tccaggttgt gagtcgctgc cggctacggc acactgaggt gctgcctgcc gaagaggaaa atgacagcct gggtgctgat ggtacccatg gagccggtgc catggagtct gcggccggtg tgctcatcaa gctcttttgt gtgcatacta aggcactgca agatgtgcag atccgcttcc agccacagct gaaccctgat gtggtggccc cactgcccac ccacactgcc cacgaggact tcacatttgg agagtctcgg cccgaactgg gctctgaggg cctggggtca gccgctcacg gctcccagcc tgacctccga cgaatcgtgg agctgcctgc acctgccgac ttcctcagtc tgagcagtga gaccaagccc aagttgatga cacctgacgc cttcatgaca cctagcgcct ccttgcagca gatcactgcc tctcccagca gcagcagcag cggtagcagc agcagcagca gcagtagcag cagctccctt acagctgtgt ctgccatgag cagcacctca gctgtggacc cctccttgac caggccacct gaggagctga ccttgagccc caagctgcag ctggatggca gcctgacaat gagcagcagt ggcagccttc aggcaagccc gcgtggcctc ctgcctggcc tgctcccagc cccagctgac aaactgactc ccaaggggcc gggccaggtg cctactgcca cctctgcact gtccctggag ctgcaggaag tggagcccct ggggctaccc caagcctccc ctagccgcac tcgttcccct gatgtcatct cctcagcttc cactgccctg tcccaggaca tccctgagat tgcatctgag gccctgtccc gtggttttgg ctcctctgca ccagagggcc ttgagccaga cagtatggct tcagccgcct cggcactgca cctgctgtcc ccacggcccc ggccagggcc cgagctcggc ccccagctcg ggcttgatgg aggccctggg gatggagatc ggcataatac cccctccctc ctggaggcag ccttgaccca ggaggcctcg actcctgaca gtcaggtttg gcccacagca cctgacatta ctcgtgagac ctgcagcacc ctggcagaaa gccccaggaa tggccttcag gaaaagcaca agagcctggc cttccaccga ccaccatatc acctgctgca gcaacgtgac agccaggatg ccagtgctga gcaaagtgac catgatgatg aggtggccag ccttgcctct gcttcaggag gctttggcac caaagttcct gctccacggc tgcctgccaa ggactggaag accaagggat cccctcgaac ctcacccaag ctcaagagga aaagcaagaa ggatgatggg gatgcagcca tgggatcccg gctcacagag caccaggtgg cagagccccc tgaggactgg ccagcactaa tttggcaaca gcagagagag ctggcagagc tgcggcacag ccaggaagag ctgctgcagc gtctgtgtac ccaactcgaa ggcctgcaga gcacagtcac aggccacgta gaacgtgccc ttgagactcg gcacgagcag gaacagcggc ggctggagcg agcactggct gaggggcagc agcggggagg gcagctgcag gagcagctga cacaacagtt gtcccaagca ctgtcgtcag ctgtagctgg gcggctagag cgcagcatac gggatgagat caagaagaca gtccctccat gtgtctcaag gagtctggag cctatggcag gccaactgag caactcagtg gctaccaagc tcacagctgt ggagggcagc atgaaagaga acatctccaa gctgctcaag tccaagaact tgactgatgc catcgcccga gcagctgcag acacattaca agggccgatg caggctgcct accgggaagc cttccagagt gtggtgctgc cggcctttga gaagagctgc caggccatgt tccagcaaat caatgatagc ttccggctgg ggacacagga atacttgcag cagctagaaa gccacatgaa gagccggaag gcacgggaac aggaggccag ggagcctgtg ctagcccagc tgcggggcct ggtcagcaca ctgcagagtg ccactgagca gatggcagcc accgtggccg gcagtgttcg tgctgaggtg cagcaccagc tgcatgtggc tgtgggcagc ctgcaggagt ccattttagc acaggtacag cgcatcgtta agggtgaggt gagtgtggcg ctcaaggagc agcaggccgc cgtcacctcc agcatcatgc aggccatgcg ctcagctgct ggcacacctg tcccctctgc ccaccttgac tgccaggccc agcaagccca tatcctgcag ctgctgcagc agggccacct caatcaggcc ttccagcagg cgctgacagc tgctgacctg aacctggtgc tgtatgtgtg tgaaactgtg gacccagccc aggtttttgg gcagccaccc tgcccgctct cccagcctgt gctcctttcc ctcatccagc agctggcatc tgaccttggc actcgaactg acctcaagct cagctacctg gaagaggccg tgatgcacct ggaccacagt gaccccatca ctcgggacca catgggctcc gttatggccc aggtgcgcca aaagcttttt cagttcctgc aggctgagcc acacaactca cttggcaaag cagctcggcg tctcagcctc atgctgcatg gcctcgtgac ccccagcctc ccttag. It is sometimes possible for the material contained within the vial of "EDC4, cDNA Clone" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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