PPP2R5C cdna clone
PPP2R5C cDNA Clone
NCBI and Uniprot Product Information
NCBI Description
The product of this gene belongs to the phosphatase 2A regulatory subunit B family. Protein phosphatase 2A is one of the four major Ser/Thr phosphatases, and it is implicated in the negative control of cell growth and division. It consists of a common heteromeric core enzyme, which is composed of a catalytic subunit and a constant regulatory subunit, that associates with a variety of regulatory subunits. The B regulatory subunit might modulate substrate selectivity and catalytic activity. This gene encodes a gamma isoform of the regulatory subunit B56 subfamily. Alternatively spliced transcript variants encoding different isoforms have been identified. [provided by RefSeq, Jul 2008]
Uniprot Description
PPP2R5C: a regulatory subunit of PP2A that might modulate substrate selectivity and catalytic activity, and also might direct the localization of the catalytic enzyme to a particular subcellular compartment. PP2A consists of a common heterodimeric core enzyme, composed of a 36 kDa catalytic subunit (subunit C) and a 65 kDa constant regulatory subunit (PR65 or subunit A), that associates with a variety of regulatory subunits. Proteins that associate with the core dimer include three families of regulatory subunits B (the R2/B/PR55/B55, R3/B''/PR72/PR130/PR59 and R5/B'/B56 families), the 48 kDa variable regulatory subunit, viral proteins, and cell signaling molecules.Three alternatively spliced human isoforms have been described.
Protein type: Motility/polarity/chemotaxis; Protein phosphatase, regulatory subunit
Chromosomal Location of Human Ortholog: 14q32.31
Cellular Component: chromosome, pericentric region; cytosol; nucleoplasm; nucleus; protein phosphatase type 2A complex
Molecular Function: protein binding
Biological Process: negative regulation of cell proliferation; proteasomal ubiquitin-dependent protein catabolic process; regulation of phosphoinositide 3-kinase cascade
Research Articles on PPP2R5C
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Product Notes
The PPP2R5C ppp2r5c (Catalog #AAA1267870) is a cDNA Clone and is intended for research purposes only. The product is available for immediate purchase. The amino acid sequence is listed below: atgttgacat gtaataaagc gggcagcagg atggtggtgg atgcggccaa ctccaatggg cctttccagc ccgtggtcct tctccatatt cgagatgttc ctcctgctga tcaagagaag ctttttatcc agaagttacg tcagtgttgc gtcctctttg actttgtttc tgatccacta agtgacctaa agtggaagga agtaaaacga gctgctttaa gtgaaatggt agaatatatc acccataatc ggaatgtgat cacagagcct atttacccag aagtagtcca tatgtttgca gttaacatgt ttcgaacatt accaccttcc tccaatccta cgggagcgga atttgacccg gaggaagatg aaccaacgtt agaagcagcc tggcctcatc tacagcttgt ttatgaattt ttcttaagat ttttagagtc tccagatttc caacctaata tagcgaagaa atatattgat cagaagtttg tattgcagct tttagagctc tttgacagtg aagatcctcg ggagagagat tttcttaaaa ccacccttca cagaatctat gggaaattcc taggcttgag agcttacatc agaaaacaga taaataatat attttatagg tttatttatg aaacagagca tcataatggc atagcagagt tactggaaat attgggaagt ataattaatg gatttgcctt accactaaaa gaagagcaca agattttctt attgaaggtg ttactacctt tgcacaaagt gaaatctctg agtgtctacc atccccagct ggcatactgt gtagtgcagt ttttagaaaa ggacagcacc ctcacggaac cagtggtgat ggcacttctc aaatactggc caaagactca cagtccaaaa gaagtaatgt tcttaaacga attagaagag attttagatg tcattgaacc atcagaattt gtgaagatca tggaacccct cttccggcag ttggccaaat gtgtctccag cccacacttc caggtggcag agcgagctct ctattactgg aataatgaat acatcatgag tttaatcagt gacaacgcag cgaagattct gcccatcatg tttccttcct tgtaccgcaa ctcaaagacc cattggaaca agtaa. It is sometimes possible for the material contained within the vial of "PPP2R5C, cDNA Clone" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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