NDFIP2 cdna clone
NDFIP2 cDNA Clone
NCBI and Uniprot Product Information
Uniprot Description
NDFIP2: Activates HECT domain-containing E3 ubiquitin-protein ligases, including ITCH, NEDD4, NEDD4L, SMURF2, WWP1 and WWP2, and consequently modulates the stability of their targets. As a result, may control many cellular processes. Recruits ITCH, NEDD4 and SMURF2 to endosomal membranes. May modulate EGFR signaling.
Protein type: Membrane protein, multi-pass; Membrane protein, integral; Adaptor/scaffold
Chromosomal Location of Human Ortholog: 13q31.1
Cellular Component: cytoplasm; endoplasmic reticulum; Golgi apparatus; intracellular membrane-bound organelle; mitochondrion; perinuclear region of cytoplasm
Molecular Function: protein binding; signal transducer activity; WW domain binding
Biological Process: negative regulation of protein transport; negative regulation of transporter activity; positive regulation of I-kappaB kinase/NF-kappaB cascade; positive regulation of protein ubiquitination
Research Articles on NDFIP2
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Product Notes
The NDFIP2 ndfip2 (Catalog #AAA1267280) is a cDNA Clone and is intended for research purposes only. The product is available for immediate purchase. The amino acid sequence is listed below: atggatcacc accagccggg gactgggcgc taccaggtgc ttcttaatga agaggataac tcagaatcat cggctataga gcagccacct acttcaaacc cagcaccgca gattgtgcag gctgcgtctt cagcaccagc acttgaaact gactcttccc ctccaccata tagtagtatt actgtggaag tacctacaac ttcagataca gaagtttacg gtgagtttta tcccgtgcca cctccctata gcgttgctac ctctcttcct acatacgatg aagctgagaa ggctaaagct gctgcaatgg cagctgcagc agcagaaaca tctcaaagaa ttcaggagga agagtgtcca ccaagagatg acttcagtga tgcagaccag ctcagagtgg ggaatgatgg cattttcatg ctggcatttt tcatggcatt tattttcaac tggcttggat tttgtttatc cttctgtatc accaatacca tagctggaag gtatggtgct atctgcggat ttggcctttc cttgatcaaa tggatcctta ttgtcaggtt ttctgattat tttactggat atttcaatgg acagtattgg ctttggtgga tatttcttgt acttggcctg ctccttttct tcagaggatt tgttaattat ctaaaagtca gaaacatgtc tgaaagtatg gcagctgctc atagaacaag gtatttcttc ttattgtag. It is sometimes possible for the material contained within the vial of "NDFIP2, cDNA Clone" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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