ARHGAP27 cdna clone
ARHGAP27 cDNA Clone
NCBI and Uniprot Product Information
NCBI Description
This gene encodes a member of a large family of proteins that activate Rho-type guanosine triphosphate (GTP) metabolizing enzymes. The encoded protein may pay a role in clathrin-mediated endocytosis. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Aug 2013]
Uniprot Description
ARHGAP27: Rho GTPase-activating protein which may be involved in clathrin-mediated endocytosis. GTPase activators for the Rho-type GTPases act by converting them to an inactive GDP-bound state. Has activity toward CDC42 and RAC1. 4 isoforms of the human protein are produced by alternative splicing.
Protein type: GAPs, Rac/Rho; GAPs
Chromosomal Location of Human Ortholog: 17q21.31
Cellular Component: cytoplasm; intracellular; nucleoplasm; nucleus
Molecular Function: GTPase activator activity; SH3 domain binding
Biological Process: positive regulation of GTPase activity; receptor-mediated endocytosis
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Product Notes
The ARHGAP27 arhgap27 (Catalog #AAA1266865) is a cDNA Clone and is intended for research purposes only. The product is available for immediate purchase. The amino acid sequence is listed below: ATGCAGCCGG GCCTGAGCCC TGGCAGCCCA GGGGACCCGC GGCCCCCCAC TCCCGAGACG GACTACCCCG AGTCGCTGAC CAGTTACCCC GAGGAGGACT ATTCTCCCGT GGGCTCTTTC GGTGAGCCCG GCCCTACCTC TCCCTTGACC ACACCCCCCG GCTGGTCTTG TCATGTCAGC CAGGACAAGC AGATGCTCTA CACCAACCAC TTCACTCAGG AGCAGTGGGT GAGGCTGGAG GACCCCCACG GGAAGCCATA CTTCTACAAT CCAGAGGACT CCTCTGTTCG ATGGGAGCTG CCCCAGGTCC CTGTCCCTGC CCCTCGAAGC ATCCATAAAT CCAGCCAGGA TGGTGACACC CCAGCCCAGG CCAGCCCTCC AGAGGAGAAG GTCCCAGCAG AGCTGGATGA GGTTGGGAGC TGGGAGGAAG TCTCTCCTGC CACAGCTGCT GTGAGGACCA AGACCTTGGA CAAGGCAGGG GTGCTCCATC GCACCAAGAC GGCAGACAAG GGAAAGCGGC TCCGGAAGAA GCACTGGAGT GCCTCCTGGA CTGTGCTGGA GGGTGGCGTC CTGACATTCT TCAAGGACTC AAAGACCTCG GCTGCAGGCG GCCTGAGGCA GCCTTCCAAG TTTTCCACCC CTGAGTACAC AGTGGAGCTG AGGGGGGCCA CTCTCTCCTG GGCCCCCAAA GACAAATCCA GTAGGAAGAA TGTGCTGGAG CTACGGAGCC GAGATGGCTC TGAGTACCTG ATCCAGCACG ACTCGGAGGC CATCATCAGC ACCTGGCATA AGGCCATTGC TCAGGGCATC CAGGAGCTGT CCGCAGAGCT GCCCCCAGAG GAGAGCGAGA GCAGCAGAGT GGACTTCGGG TCGAGCGAGC GCTTGGGAAG CTGGCAGGAG AAAGAGGAGG ACGCGCGACC GAATGCAGCC GCGCCCGCCC TGGGCCCCGT GGGCCTGGAG AGCGACTTGA GCAAGGTCCG GCACAAGCTC CGCAAGTTCC TCCAGAGGCG GCCCACACTG CAGTCGCTGC GGGAGAAGGG CTACATCAAA GACCAGGTGT TCGGCTGCGC GCTGGCCGCG CTGTGTGAGC GCGAGAGGAG CCGGGTGCCA CGCTTCGTGC AGCAGTGCAT CCGCGCCGTC GAGGCCCGCG GGCTGGACAT CGACGGGCTG TACCGCATCA GTGGAAACCT GGCCACCATC CAGAAGCTAC GCTATAAGGT GGACCACGAT GAGCGCCTTG ACCTGGATGA CGGGCGCTGG GAGGACGTCC ACGTTATCAC CGGAGCCCTG AAGCTCTTCT TTCGGGAGCT GCCCGAGCCC CTCTTCCCCT TCTCGCACTT CCGCCAGTTC ATTGCGGCCA TCAAGTTGCA GGACCAGGCC CGGCGCAGCC GCTGTGTGCG TGACTTGGTG CGCTCGCTGC CCGCTCCCAA CCACGACACT CTGCGGATGC TCTTCCAGCA CCTCTGCCGG GTGATCGAGC ACGGCGAGCA GAACCGCATG TCGGTGCAGA GCGTGGCCAT TGTGTTCGGG CCCACGCTGC TGCGGCCCGA GGTGGAAGAG ACCAGCATGC CCATGACCAT GGTGTTCCAG AACCAGGTGG TGGAGCTCAT CCTGCAGCAG TGCGCGGACA TCTTCCCGCC GCACTGA. It is sometimes possible for the material contained within the vial of "ARHGAP27, cDNA Clone" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
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