Transcriptional regulator IE63 (ORF63) Recombinant Protein | ORF63 recombinant protein
Recombinant Varicella-zoster virus Transcriptional regulator IE63 (ORF63)
Purity
Greater or equal to 85% purity as determined by SDS-PAGE.
Synonyms
Transcriptional regulator IE63 (ORF63); Recombinant Varicella-zoster virus Transcriptional regulator IE63 (ORF63); ORF63 recombinant protein
Host
E Coli or Yeast or Baculovirus or Mammalian Cell
Purity/Purification
Greater or equal to 85% purity as determined by SDS-PAGE.
Form/Format
Lyophilized or liquid (Format to be determined during the manufacturing process)
Sequence Positions
1-278, Full length protein
Sequence
MFCTSPATRGDSSESKPGASVDVNGKMEYGSAPGPLNGRDTSRGPGAFCTPGWEIHPARLVEDINRVFLCIAQSSGRVTRDSRRLRRICLDFYLMGRTRQRPTLACWEELLQLQPTQTQCLRATLMEVSHRPPRGEDGFIEAPNVPLHRSALECDVSDDGGEDDSDDDGSTPSDVIEFRDSDAESSDGEDFIVEEESEESTDSCEPDGVPGDCYRDGDGCNTPSPKRPQRAIERYAGAETAEYTAAKALTALGEGGVDWKRRRHEAPRRHDIPPPHGV
Sequence Length
278
Species
Varicella-zoster virus (strain Dumas) (HHV-3) (Human herpesvirus 3)
Preparation and Storage
Store at -20 degrees C. For long-term storage, store at -20 degrees C or -80 degrees C. Store working aliquots at 4 degrees C for up to one week. Repeated freezing and thawing is not recommended.
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
Molecular Weight
30,495 Da
NCBI Official Full Name
regulatory protein ICP22
NCBI Official Symbol
ORF63
NCBI Protein Information
required for expression of a subset of late genes
UniProt Protein Name
Transcriptional regulator ICP22 homolog
Protein Family
UniProt Gene Name
ORF63
UniProt Synonym Gene Names
IE63
Uniprot Description
Immediate early (EI) protein that functions as a transcriptional regulator of cellular and viral mRNAs mainly by interacting with several general transcription factors thereby disorganizing the preinitiation complex at certain promoters. May additionally help to regulate levels of histones in virus-infected cells by interacting with host ASF1. By inhibiting host transcriptional program, IE63 plays a major role in the ability of VZV to overcome the innate immune response to the virus.
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Product Notes
The ORF63 orf63 (Catalog #AAA1264310) is a Recombinant Protein produced from E Coli or Yeast or Baculovirus or Mammalian Cell and is intended for research purposes only. The product is available for immediate purchase. The immunogen sequence is 1-278, Full length protein. The amino acid sequence is listed below: MFCTSPATRG DSSESKPGAS VDVNGKMEYG SAPGPLNGRD TSRGPGAFCT PGWEIHPARL VEDINRVFLC IAQSSGRVTR DSRRLRRICL DFYLMGRTRQ RPTLACWEEL LQLQPTQTQC LRATLMEVSH RPPRGEDGFI EAPNVPLHRS ALECDVSDDG GEDDSDDDGS TPSDVIEFRD SDAESSDGED FIVEEESEES TDSCEPDGVP GDCYRDGDGC NTPSPKRPQR AIERYAGAET AEYTAAKALT ALGEGGVDWK RRRHEAPRRH DIPPPHGV. It is sometimes possible for the material contained within the vial of "Transcriptional regulator IE63 (ORF63), Recombinant Protein" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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