Cyclin-D1-binding protein 1 (CCNDBP1) Recombinant Protein | CCNDBP1 recombinant protein
Recombinant Human Cyclin-D1-binding protein 1 (CCNDBP1)
NCBI and Uniprot Product Information
NCBI Description
This gene was identified by the interaction of its gene product with Grap2, a leukocyte-specific adaptor protein important for immune cell signaling. The protein encoded by this gene was shown to interact with cyclin D. Transfection of this gene in cells was reported to reduce the phosphorylation of Rb gene product by cyclin D-dependent protein kinase, and inhibit E2F1-mediated transcription activity. This protein was also found to interact with helix-loop-helix protein E12 and is thought to be a negative regulator of liver-specific gene expression. Several alternatively spliced variants have been found for this gene. [provided by RefSeq, Apr 2009]
Uniprot Description
May negatively regulate cell cycle progression. May act at least in part via inhibition of the cyclin-D1/CDK4 complex, thereby preventing phosphorylation of RB1 and blocking E2F-dependent transcription.
Research Articles on CCNDBP1
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Product Notes
The CCNDBP1 ccndbp1 (Catalog #AAA1257434) is a Recombinant Protein produced from E Coli or Yeast or Baculovirus or Mammalian Cell and is intended for research purposes only. The product is available for immediate purchase. The immunogen sequence is 2-360, Full length protein. The amino acid sequence is listed below: ASATAPAAAV PTLASPLEQL RHLAEELRLL LPRVRVGEAQ ETTEEFNREM FWRRLNEAAV TVSREATTLT IVFSQLPLPS PQETQKFCEQ VHAAIKAFIA VYYLLPKDQG ITLRKLVRGA TLDIVDGMAQ LMEVLSVTPT QSPENNDLIS YNSVWVACQQ MPQIPRDNKA AALLMLTKNV DFVKDAHEEM EQAVEECDPY SGLLNDTEEN NSDNHNHEDD VLGFPSNQDL YWSEDDQELI IPCLALVRAS KACLKKIRML VAENGKKDQV AQLDDIVDIS DEISPSVDDL ALSIYPPMCH LTVRINSAKL VSVLKKALEI TKASHVTPQP EDSWIPLLIN AIDHCMNRIK ELTQSELEL. It is sometimes possible for the material contained within the vial of "Cyclin-D1-binding protein 1 (CCNDBP1), Recombinant Protein" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
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