Centromere/kinetochore protein zw10 homolog (Zw10) Recombinant Protein | Zw10 recombinant protein
Recombinant Mouse Centromere/kinetochore protein zw10 homolog (Zw10)
Gene Names
Zw10; MmZw10; 6330566F14Rik
Purity
Greater or equal to 85% purity as determined by SDS-PAGE.
Synonyms
Centromere/kinetochore protein zw10 homolog (Zw10); Recombinant Mouse Centromere/kinetochore protein zw10 homolog (Zw10); Zw10 recombinant protein
Host
E Coli or Yeast or Baculovirus or Mammalian Cell
Purity/Purification
Greater or equal to 85% purity as determined by SDS-PAGE.
Form/Format
Lyophilized or liquid (Format to be determined during the manufacturing process)
Sequence Positions
2-779, Full length protein
Sequence
ASFVTEVLAHSGSLEKEDLGTRISRLTRRVEEIKGEVCNMISKKYSEFLPTMQSAQALVTQVDTLSNDIDQLKSRIETEVCRDLHISTVEFTNLKQQLERDSVVLTLLKQLQEFSSAIEEYNSALAEKKYIPAARHLEEAQECLKLLKSRKCFDLKMLKSLSMELTVQKQNILYHLGEDWQKLVVWKFPPAKDTSSLESCLQTELHLCTEQPEKEDMTPLPSISSVLLAFSILGELPTKLKSFGQMLLKYILKPLVTCPSLHAVIERQPSSVSICFESLTTDLEHPSPPEAFAKIRLVLEVLQKQLLDLPLDADLEIGKVPGIVLAEMLGEGIWEDLSECLIRNCLVYSIPTNSSKLQEYEEIIQSTEEFEKFLKEMRFLKGDTTDLLKYARNINSHFANKKCQDVIVAARNLMTSEIHNTVKIGPDCKEALPDLPSPDADHKLQVQTVCKAQFTDAGNLEPETSLDPQSFSLPTCRISEAVKKLMELAYQTLLEATTSSDQCAVQLFYSVRNIFHLFHDVVPTYHKENLRKLPQLAAIHHNNCMYIAHHLLTLGHQFRLRLAPILCDGTTTFVDLVPGFRRLGTECFLAQMQAQKGELLERLSSARSFANMDDEENYSAASKAVRQVLHQLRRLGIVWQDVLPVNIYCKAMGTLLNTAIAEMMSRITALEDISTEDGDRLYSLCKTVMDEGPQVFAPLSDENKNKKYQEEVPVYVSKWMPFKELMIMLQASLQEIGDRWADGKGPLATAFPSSEVKALIRALFQNTERRAAALAKIK
Sequence Length
778
Species
Mouse
Preparation and Storage
Store at -20 degrees C. For long-term storage, store at -20 degrees C or -80 degrees C. Store working aliquots at 4 degrees C for up to one week. Repeated freezing and thawing is not recommended.
Related Product Information for Zw10 recombinant protein
This gene encodes a protein that is one of many involved in mechanisms to ensure proper chromosome segregation during cell division. The encoded protein binds to centromeres during the prophase, metaphase, and early anaphase cell division stages and to kinetochore microtubules during metaphase.
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
Molecular Weight
88,063 Da
NCBI Official Full Name
centromere/kinetochore protein zw10 homolog
NCBI Official Synonym Full Names
zw10 kinetochore protein
NCBI Official Symbol
Zw10
NCBI Official Synonym Symbols
MmZw10; 6330566F14Rik
NCBI Protein Information
centromere/kinetochore protein zw10 homolog
UniProt Protein Name
Centromere/kinetochore protein zw10 homolog
Protein Family
UniProt Gene Name
Zw10
Uniprot Description
Essential component of the mitotic checkpoint, which prevents cells from prematurely exiting mitosis. Required for the assembly of the dynein-dynactin and MAD1-MAD2 complexes onto kinetochores. Its function related to the spindle assembly machinery is proposed to depend on its association in the mitotic RZZ complex. Involved in regulation of membrane traffic between the Golgi and the endoplasmic reticulum (ER); the function is proposed to depend on its association in the interphase NRZ complex which is believed to play a role in SNARE assembly at the ER ().
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Product Notes
The Zw10 zw10 (Catalog #AAA1257344) is a Recombinant Protein produced from E Coli or Yeast or Baculovirus or Mammalian Cell and is intended for research purposes only. The product is available for immediate purchase. The immunogen sequence is 2-779, Full length protein. The amino acid sequence is listed below: ASFVTEVLAH SGSLEKEDLG TRISRLTRRV EEIKGEVCNM ISKKYSEFLP TMQSAQALVT QVDTLSNDID QLKSRIETEV CRDLHISTVE FTNLKQQLER DSVVLTLLKQ LQEFSSAIEE YNSALAEKKY IPAARHLEEA QECLKLLKSR KCFDLKMLKS LSMELTVQKQ NILYHLGEDW QKLVVWKFPP AKDTSSLESC LQTELHLCTE QPEKEDMTPL PSISSVLLAF SILGELPTKL KSFGQMLLKY ILKPLVTCPS LHAVIERQPS SVSICFESLT TDLEHPSPPE AFAKIRLVLE VLQKQLLDLP LDADLEIGKV PGIVLAEMLG EGIWEDLSEC LIRNCLVYSI PTNSSKLQEY EEIIQSTEEF EKFLKEMRFL KGDTTDLLKY ARNINSHFAN KKCQDVIVAA RNLMTSEIHN TVKIGPDCKE ALPDLPSPDA DHKLQVQTVC KAQFTDAGNL EPETSLDPQS FSLPTCRISE AVKKLMELAY QTLLEATTSS DQCAVQLFYS VRNIFHLFHD VVPTYHKENL RKLPQLAAIH HNNCMYIAHH LLTLGHQFRL RLAPILCDGT TTFVDLVPGF RRLGTECFLA QMQAQKGELL ERLSSARSFA NMDDEENYSA ASKAVRQVLH QLRRLGIVWQ DVLPVNIYCK AMGTLLNTAI AEMMSRITAL EDISTEDGDR LYSLCKTVMD EGPQVFAPLS DENKNKKYQE EVPVYVSKWM PFKELMIMLQ ASLQEIGDRW ADGKGPLATA FPSSEVKALI RALFQNTERR AAALAKIK. It is sometimes possible for the material contained within the vial of "Centromere/kinetochore protein zw10 homolog (Zw10), Recombinant Protein" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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