Calpain-2 catalytic subunit (Capn2) Recombinant Protein | Capn2 recombinant protein
Recombinant Mouse Calpain-2 catalytic subunit (Capn2)
Gene Names
Capn2; Capa2; CALP80; Capa-2; AI326419; m-calpin; m-calpain
Purity
Greater or equal to 85% purity as determined by SDS-PAGE.
Synonyms
Calpain-2 catalytic subunit (Capn2); Recombinant Mouse Calpain-2 catalytic subunit (Capn2); Capn2 recombinant protein
Host
E Coli or Yeast or Baculovirus or Mammalian Cell
Purity/Purification
Greater or equal to 85% purity as determined by SDS-PAGE.
Form/Format
Lyophilized or liquid (Format to be determined during the manufacturing process)
Sequence Positions
20-700, Full length protein
Sequence
SHERAIKYLNQDYETLRNECLEAGALFQDPSFPALPSSLGYKELGPYSSKTRGIEWKRPTEICADPQFIIGGATRTDICQGALGDCWLLAAIASLTLNEEILARVVPPDQSFQENYAGIFHFQFWQYGEWVEVVVDDRLPTKDGELLFVHSAEGSEFWSALLEKAYAKINGCYEALSGGATTEGFEDFTGGIAEWYELRKPPPNLFKIIQKALEKGSLLGCSIDITSAADSEAVTYQKLVKGHAYSVTGAEEVESSGSLQKLIRIRNPWGQVEWTGKWNDNCPSWNTVDPEVRANLTERQEDGEFWMSFSDFLRHYSRLEICNLTPDTLTCDSYKKWKLTKMDGNWRRGSTAGGCRNYPNTFWMNPQYLIKLEEEDEDEEDGERGCTFLVGLIQKHRRRQRKMGEDMHTIGFGIYEVPEELTGQTNIHLGKNFFLTTRARERSDTFINLREVLNRFKLPPGEYVLVPSTFEPHKDGDFCIRVFSEKKADYQAVDDEIEANIEEIDANEEDIDDGFRRLFVQLAGEDAEISAFELQTILRRVLAKRQDIKSDGFSIETCKIMVDMLDEDGSGKLGLKEFYILWTKIQKYQKIYREIDVDRSGTMNSYEMRKALEEAGFKLPCQLHQVIVARFADDELIIDFDNFVRCLVRLETLFKIFKQLDPENTGTIQLNLASWLSFSVL
Sequence Length
681
Species
Mouse
Preparation and Storage
Store at -20 degrees C. For long-term storage, store at -20 degrees C or -80 degrees C. Store working aliquots at 4 degrees C for up to one week. Repeated freezing and thawing is not recommended.
Related Product Information for Capn2 recombinant protein
The calpains, calcium-activated neutral proteases, are nonlysosomal, intracellular cysteine proteases. The mammalian calpains include ubiquitous, stomach-specific, and muscle-specific proteins. The ubiquitous enzymes consist of heterodimers with distinct large, catalytic subunits associated with a common small, regulatory subunit. This gene encodes the large subunit of the ubiquitous enzyme, calpain 2. Multiple heterogeneous transcriptional start sites in the 5 UTR have been reported. Two transcript variants encoding different isoforms have been found for this gene.
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
Molecular Weight
79,872 Da
NCBI Official Full Name
calpain-2 catalytic subunit
NCBI Official Synonym Full Names
calpain 2
NCBI Official Symbol
Capn2
NCBI Official Synonym Symbols
Capa2; CALP80; Capa-2; AI326419; m-calpin; m-calpain
NCBI Protein Information
calpain-2 catalytic subunit
UniProt Protein Name
Calpain-2 catalytic subunit
Protein Family
UniProt Gene Name
Capn2
UniProt Synonym Gene Names
CALP80; CANP 2; M-calpain
Uniprot Description
Calcium-regulated non-lysosomal thiol-protease which catalyzes limited proteolysis of substrates involved in cytoskeletal remodeling and signal transduction. Proteolytically cleaves MYOC at 'Arg-226' (). Proteolytically cleaves CPEB3 following neuronal stimulation which abolishes CPEB3 translational repressor activity, leading to translation of CPEB3 target mRNAs (PubMed:22711986).
Research Articles on Capn2
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Product Notes
The Capn2 capn2 (Catalog #AAA1256526) is a Recombinant Protein produced from E Coli or Yeast or Baculovirus or Mammalian Cell and is intended for research purposes only. The product is available for immediate purchase. The immunogen sequence is 20-700, Full length protein. The amino acid sequence is listed below: SHERAIKYLN QDYETLRNEC LEAGALFQDP SFPALPSSLG YKELGPYSSK TRGIEWKRPT EICADPQFII GGATRTDICQ GALGDCWLLA AIASLTLNEE ILARVVPPDQ SFQENYAGIF HFQFWQYGEW VEVVVDDRLP TKDGELLFVH SAEGSEFWSA LLEKAYAKIN GCYEALSGGA TTEGFEDFTG GIAEWYELRK PPPNLFKIIQ KALEKGSLLG CSIDITSAAD SEAVTYQKLV KGHAYSVTGA EEVESSGSLQ KLIRIRNPWG QVEWTGKWND NCPSWNTVDP EVRANLTERQ EDGEFWMSFS DFLRHYSRLE ICNLTPDTLT CDSYKKWKLT KMDGNWRRGS TAGGCRNYPN TFWMNPQYLI KLEEEDEDEE DGERGCTFLV GLIQKHRRRQ RKMGEDMHTI GFGIYEVPEE LTGQTNIHLG KNFFLTTRAR ERSDTFINLR EVLNRFKLPP GEYVLVPSTF EPHKDGDFCI RVFSEKKADY QAVDDEIEAN IEEIDANEED IDDGFRRLFV QLAGEDAEIS AFELQTILRR VLAKRQDIKS DGFSIETCKI MVDMLDEDGS GKLGLKEFYI LWTKIQKYQK IYREIDVDRS GTMNSYEMRK ALEEAGFKLP CQLHQVIVAR FADDELIIDF DNFVRCLVRL ETLFKIFKQL DPENTGTIQL NLASWLSFSV L. It is sometimes possible for the material contained within the vial of "Calpain-2 catalytic subunit (Capn2), Recombinant Protein" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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