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Ectonucleoside triphosphate diphosphohydrolase 6 (ENTPD6) Recombinant Protein | ENTPD6 recombinant protein

Recombinant Human Ectonucleoside triphosphate diphosphohydrolase 6 (ENTPD6)

Gene Names
ENTPD6; CD39L2; IL6ST2; IL-6SAG; NTPDase-6; dJ738P15.3
Purity
Greater or equal to 85% purity as determined by SDS-PAGE.
Synonyms
Ectonucleoside triphosphate diphosphohydrolase 6 (ENTPD6); Recombinant Human Ectonucleoside triphosphate diphosphohydrolase 6 (ENTPD6); ENTPD6 recombinant protein
Ordering
Host
E Coli or Yeast or Baculovirus or Mammalian Cell
Purity/Purification
Greater or equal to 85% purity as determined by SDS-PAGE.
Form/Format
Lyophilized or liquid (Format to be determined during the manufacturing process)
Sequence Positions
1-484
Sequence
MKKGIRYETSRKTSYIFQQPQHGPWQTRMRKISNHGSLRVAKVAYPLGLCVGVFIYVAYIKWHRATATQAFFSITRAAPGARWGQQAHSPLGTAADGHEVFYGIMFDAGSTGTRVHVFQFTRPPRETPTLTHETFKALKPGLSAYADDVEKSAQGIRELLDVAKQDIPFDFWKATPLVLKATAGLRLLPGEKAQKLLQKVKKVFKASPFLVGDDCVSIMNGTDEGVSAWITINFLTGSLKTPGGSSVGMLDLGGGSTQIAFLPRVEGTLQASPPGYLTALRMFNRTYKLYSYSYLGLGLMSARLAILGGVEGQPAKDGKELVSPCLSPSFKGEWEHAEVTYRVSGQKAAASLHELCAARVSEVLQNRVHRTEEVKHVDFYAFSYYYDLAAGVGLIDAEKGGSLVVGDFEIAAKYVCRTLETQPQSSPFSCMDLTYVSLLLQEFGFPRSKVLKLTRKIDNVETSWALGAIFHYIDSLNRQKSPAS
Sequence Length
467
Species
Homo sapiens (Human)
Preparation and Storage
Store at -20 degree C. For extended storage, store at -20 or -80 degree C.
Related Product Information for ENTPD6 recombinant protein
ENTPD6; CD39L2, IL6ST2

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
955
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
Molecular Weight
53,246 Da
NCBI Official Full Name
ectonucleoside triphosphate diphosphohydrolase 6 isoform 2
NCBI Official Synonym Full Names
ectonucleoside triphosphate diphosphohydrolase 6 (putative)
NCBI Official Symbol
ENTPD6
NCBI Official Synonym Symbols
CD39L2; IL6ST2; IL-6SAG; NTPDase-6; dJ738P15.3
NCBI Protein Information
ectonucleoside triphosphate diphosphohydrolase 6; NTPDase 6; CD39-like 2; CD39 antigen-like 2; HCV-E2 binding protein 1; interleukin 6 signal transducer-2; ectonucleoside triphosphate diphosphohydrolase 6 (putative function)
UniProt Protein Name
Ectonucleoside triphosphate diphosphohydrolase 6
UniProt Gene Name
ENTPD6
UniProt Synonym Gene Names
CD39L2; IL6ST2; NTPDase 6
UniProt Entry Name
ENTP6_HUMAN

NCBI Description

ENTPD6 is similar to E-type nucleotidases (NTPases). NTPases, such as CD39, mediate catabolism of extracellular nucleotides. ENTPD6 contains 4 apyrase-conserved regions which is characteristic of NTPases. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]

Uniprot Description

ENTPD6: Might support glycosylation reactions in the Golgi apparatus and, when released from cells, might catalyze the hydrolysis of extracellular nucleotides. Hydrolyzes preferentially nucleoside 5'-diphosphates, nucleoside 5'-triphosphates are hydrolyzed only to a minor extent, there is no hydrolysis of nucleoside 5'-monophosphates. The order of activity with different substrates is GDP > IDP >> UDP = CDP >> ADP. Belongs to the GDA1/CD39 NTPase family. 2 isoforms of the human protein are produced by alternative splicing.

Protein type: Hydrolase; Nucleotide Metabolism - pyrimidine; Nucleotide Metabolism - purine; Membrane protein, integral; EC 3.6.1.6

Chromosomal Location of Human Ortholog: 20p11.21

Cellular Component: Golgi membrane; extracellular space; cell surface; integral to membrane; plasma membrane

Molecular Function: nucleoside-triphosphatase activity; guanosine-5'-triphosphate,3'-diphosphate diphosphatase activity; uridine-diphosphatase activity

Biological Process: response to magnesium ion; metabolic process; response to calcium ion

Research Articles on ENTPD6

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Product Notes

The ENTPD6 entpd6 (Catalog #AAA1229897) is a Recombinant Protein produced from E Coli or Yeast or Baculovirus or Mammalian Cell and is intended for research purposes only. The product is available for immediate purchase. The immunogen sequence is 1-484. The amino acid sequence is listed below: MKKGIRYETS RKTSYIFQQP QHGPWQTRMR KISNHGSLRV AKVAYPLGLC VGVFIYVAYI KWHRATATQA FFSITRAAPG ARWGQQAHSP LGTAADGHEV FYGIMFDAGS TGTRVHVFQF TRPPRETPTL THETFKALKP GLSAYADDVE KSAQGIRELL DVAKQDIPFD FWKATPLVLK ATAGLRLLPG EKAQKLLQKV KKVFKASPFL VGDDCVSIMN GTDEGVSAWI TINFLTGSLK TPGGSSVGML DLGGGSTQIA FLPRVEGTLQ ASPPGYLTAL RMFNRTYKLY SYSYLGLGLM SARLAILGGV EGQPAKDGKE LVSPCLSPSF KGEWEHAEVT YRVSGQKAAA SLHELCAARV SEVLQNRVHR TEEVKHVDFY AFSYYYDLAA GVGLIDAEKG GSLVVGDFEI AAKYVCRTLE TQPQSSPFSC MDLTYVSLLL QEFGFPRSKV LKLTRKIDNV ETSWALGAIF HYIDSLNRQK SPAS. It is sometimes possible for the material contained within the vial of "Ectonucleoside triphosphate diphosphohydrolase 6 (ENTPD6), Recombinant Protein" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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