Ectonucleoside triphosphate diphosphohydrolase 6 (ENTPD6) Recombinant Protein | ENTPD6 recombinant protein
Recombinant Human Ectonucleoside triphosphate diphosphohydrolase 6 (ENTPD6)
NCBI and Uniprot Product Information
NCBI Description
ENTPD6 is similar to E-type nucleotidases (NTPases). NTPases, such as CD39, mediate catabolism of extracellular nucleotides. ENTPD6 contains 4 apyrase-conserved regions which is characteristic of NTPases. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]
Uniprot Description
ENTPD6: Might support glycosylation reactions in the Golgi apparatus and, when released from cells, might catalyze the hydrolysis of extracellular nucleotides. Hydrolyzes preferentially nucleoside 5'-diphosphates, nucleoside 5'-triphosphates are hydrolyzed only to a minor extent, there is no hydrolysis of nucleoside 5'-monophosphates. The order of activity with different substrates is GDP > IDP >> UDP = CDP >> ADP. Belongs to the GDA1/CD39 NTPase family. 2 isoforms of the human protein are produced by alternative splicing.
Protein type: Hydrolase; Nucleotide Metabolism - pyrimidine; Nucleotide Metabolism - purine; Membrane protein, integral; EC 3.6.1.6
Chromosomal Location of Human Ortholog: 20p11.21
Cellular Component: Golgi membrane; extracellular space; cell surface; integral to membrane; plasma membrane
Molecular Function: nucleoside-triphosphatase activity; guanosine-5'-triphosphate,3'-diphosphate diphosphatase activity; uridine-diphosphatase activity
Biological Process: response to magnesium ion; metabolic process; response to calcium ion
Research Articles on ENTPD6
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Product Notes
The ENTPD6 entpd6 (Catalog #AAA1229897) is a Recombinant Protein produced from E Coli or Yeast or Baculovirus or Mammalian Cell and is intended for research purposes only. The product is available for immediate purchase. The immunogen sequence is 1-484. The amino acid sequence is listed below: MKKGIRYETS RKTSYIFQQP QHGPWQTRMR KISNHGSLRV AKVAYPLGLC VGVFIYVAYI KWHRATATQA FFSITRAAPG ARWGQQAHSP LGTAADGHEV FYGIMFDAGS TGTRVHVFQF TRPPRETPTL THETFKALKP GLSAYADDVE KSAQGIRELL DVAKQDIPFD FWKATPLVLK ATAGLRLLPG EKAQKLLQKV KKVFKASPFL VGDDCVSIMN GTDEGVSAWI TINFLTGSLK TPGGSSVGML DLGGGSTQIA FLPRVEGTLQ ASPPGYLTAL RMFNRTYKLY SYSYLGLGLM SARLAILGGV EGQPAKDGKE LVSPCLSPSF KGEWEHAEVT YRVSGQKAAA SLHELCAARV SEVLQNRVHR TEEVKHVDFY AFSYYYDLAA GVGLIDAEKG GSLVVGDFEI AAKYVCRTLE TQPQSSPFSC MDLTYVSLLL QEFGFPRSKV LKLTRKIDNV ETSWALGAIF HYIDSLNRQK SPAS. It is sometimes possible for the material contained within the vial of "Ectonucleoside triphosphate diphosphohydrolase 6 (ENTPD6), Recombinant Protein" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
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