Cyclic AMP-responsive element-binding protein 3-like protein 2 (creb3l2) Recombinant Protein | creb3l2 recombinant protein

Recombinant Xenopus laevis Cyclic AMP-responsive element-binding protein 3-like protein 2 (creb3l2)

• Gene Names: creb3l2; bbf2h7
• Purity: Greater or equal to 85% purity as determined by SDS-PAGE.
• Synonyms: Cyclic AMP-responsive element-binding protein 3-like protein 2 (creb3l2); Recombinant Xenopus laevis Cyclic AMP-responsive element-binding protein 3-like protein 2 (creb3l2); Cyclic AMP-responsive element-binding protein 3-like protein 2; cAMP-responsive element-binding protein 3-like protein 2Cleaved into the following chain:; 1. Processed cyclic AMP-responsive element-binding protein 3-like protein 2; creb3l2 recombinant protein

• Host: E Coli or Yeast or Baculovirus or Mammalian Cell
• Purity/Purification: Greater or equal to 85% purity as determined by SDS-PAGE.
• Form/Format: Lyophilized or liquid (Format to be determined during the manufacturing process)
• Sequence Positions: 1-382
• Sequence: MEIMESGDPV IQWDRKLSEL SEAAESDSLY NNTPFSELLD DSALLDVLGQ LMGDPFLTEK YEMMEVEMNP SSPSPMIKAE HSYSLCGDSR PQSPFTHASS DDNFSDTDLT GDDWCLNGEL TATTPTTKIK VEIPLEETPG LTPSVTLATS AVSASPEVGV SSQLPVPEQV KLLSPVALPQ IKLEPHEVDQ FLNLCPKEVA PTEALQMPPT PPSSHGSDSE GGQSPTRSLP PSSPVQSQAG GKMAARSPSA LSNSPLLTAP HKLQGSGPLM LTEEEKRTLV AEGYPIPTKL PLTKAEEKAL KKIRRKIKNK ISAQESRRKK KEYMDSLEKR VENSSSENSE LRKKVEVLES TNRTLLQQLQ RLQAMVTGKV TRSCKAAGTQ TG
• Sequence Length: 382

• Species: Xenopus laevis (African clawed frog)
• Preparation and Storage: Store at -20 degrees C. For long-term storage, store at -20 degrees C or -80 degrees C. Store working aliquots at 4 degrees C for up to one week. Repeated freezing and thawing is not recommended.

NCBI and Uniprot Product Information

• NCBI GI #: 148231257
• NCBI GeneID: 100037168
• NCBI Accession #: NP_001091333.1
• NCBI GenBank Nucleotide #: NM_001097864.1
• UniProt Accession #: A2VD01
• Molecular Weight: 57,625 Da
• NCBI Official Full Name: cyclic AMP-responsive element-binding protein 3-like protein 2
• NCBI Official Synonym Full Names: cAMP responsive element binding protein 3-like 2<
• NCBI Official Symbol: creb3l2
• NCBI Official Synonym Symbols: bbf2h7
• NCBI Protein Information: cyclic AMP-responsive element-binding protein 3-like protein 2; cAMP-responsive element-binding protein 3-like protein 2
• UniProt Protein Name: Cyclic AMP-responsive element-binding protein 3-like protein 2
• Protein Family: Cyclic AMP-responsive element-binding protein 3-like protein
• UniProt Gene Name: creb3l2
• UniProt Synonym Gene Names: cAMP-responsive element-binding protein 3-like protein 2
• UniProt Entry Name: CR3L2_XENLA

Uniprot Description

Transcription factor involved in unfolded protein response (UPR). In the absence of endoplasmic reticulum (ER) stress, inserted into ER membranes, with N-terminal DNA-binding and transcription activation domains oriented toward the cytosolic face of the membrane. In response to ER stress, transported to the Golgi, where it is cleaved in a site-specific manner by resident proteases S1P/mbtps1 and S2P/mbtps2. The released N-terminal cytosolic domain is translocated to the nucleus to effect transcription of specific target genes. Plays a critical role in chondrogenesis. May protect neuroblastoma cells from ER stress-induced death. In vitro activates transcription of target genes via direct binding to the CRE site.