Delta (14)-sterol reductase (TM7SF2) Recombinant Protein | TM7SF2 recombinant protein
Recombinant Human Delta (14)-sterol reductase (TM7SF2)
Gene Names
TM7SF2; ANG1; NET47; DHCR14A
Purity
Greater or equal to 85% purity as determined by SDS-PAGE.
Synonyms
Delta (14)-sterol reductase (TM7SF2); Recombinant Human Delta (14)-sterol reductase (TM7SF2); Recombinant Delta (14)-sterol reductase (TM7SF2); Delta(14)-sterol reductase; Delta-14-SR EC= 1.3.1.70; Another new gene 1 protein C-14 sterol reductase Putative sterol reductase SR-1 Sterol C14-reductase Transmembrane 7 superfamily member 2; TM7SF2 recombinant protein
Host
E Coli or Yeast or Baculovirus or Mammalian Cell
Purity/Purification
Greater or equal to 85% purity as determined by SDS-PAGE.
Form/Format
Lyophilized or liquid (Format to be determined during the manufacturing process)
Sequence Positions
1-418
Sequence
MAPTQGPRAPLEFGGPLGAAALLLLLPATMFHLLLAARSGPARLLGPPASLPGLEVLWSPRALLLWLAWLGLQAALYLLPARKVAEGQELKDKSRLRYPINGFQALVLTALLVGLGMSAGLPLGALPEMLLPLAFVATLTAFIFSLFLYMKAQVAPVSALAPGGNSGNPIYDFFLGRELNPRICFFDFKYFCELRPGLIGWVLINLALLMKEAELRGSPSLAMWLVNGFQLLYVGDALWHEEAVLTTMDITHDGFGFMLAFGDMAWVPFTYSLQAQFLLHHPQPLGLPMASVICLINATGYYIFRGANSQKNTFRKNPSDPRVAGLETISTATGRKLLVSGWWGMVRHPNYLGDLIMALAWSLPCGVSHLLPYFYLLYFTALLVHREARDERQCLQKYGLAWQEYCRRVPYRIMPYIY
Sequence Length
418
Species
Homo sapiens (Human)
Preparation and Storage
Store at -20 degree C. For extended storage, store at -20 or -80 degree C.
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
Molecular Weight
46,406 Da
NCBI Official Full Name
delta(14)-sterol reductase
NCBI Official Synonym Full Names
transmembrane 7 superfamily member 2
NCBI Official Symbol
TM7SF2
NCBI Official Synonym Symbols
ANG1; NET47; DHCR14A
NCBI Protein Information
delta(14)-sterol reductase; delta(14)-sterol reductase; delta-14-SR; sterol C14-reductase; C-14 sterol reductase; another new gene 1 protein; putative sterol reductase SR-1
UniProt Protein Name
Delta(14)-sterol reductase
UniProt Gene Name
TM7SF2
UniProt Synonym Gene Names
ANG1; Delta-14-SR
UniProt Entry Name
ERG24_HUMAN
Uniprot Description
TM7SF2: Involved in the conversion of lanosterol to cholesterol. Belongs to the ERG4/ERG24 family. 2 isoforms of the human protein are produced by alternative splicing.
Protein type: EC 1.3.1.70; Membrane protein, multi-pass; Oxidoreductase; Membrane protein, integral; Endoplasmic reticulum; Lipid Metabolism - steroid biosynthesis
Chromosomal Location of Human Ortholog: 11q13
Cellular Component: endoplasmic reticulum membrane; endoplasmic reticulum; integral to plasma membrane; receptor complex
Molecular Function: delta14-sterol reductase activity
Biological Process: cholesterol biosynthetic process
Research Articles on TM7SF2
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Product Notes
The TM7SF2 tm7sf2 (Catalog #AAA1212904) is a Recombinant Protein produced from E Coli or Yeast or Baculovirus or Mammalian Cell and is intended for research purposes only. The product is available for immediate purchase. The immunogen sequence is 1-418. The amino acid sequence is listed below: MAPTQGPRAP LEFGGPLGAA ALLLLLPATM FHLLLAARSG PARLLGPPAS LPGLEVLWSP RALLLWLAWL GLQAALYLLP ARKVAEGQEL KDKSRLRYPI NGFQALVLTA LLVGLGMSAG LPLGALPEML LPLAFVATLT AFIFSLFLYM KAQVAPVSAL APGGNSGNPI YDFFLGRELN PRICFFDFKY FCELRPGLIG WVLINLALLM KEAELRGSPS LAMWLVNGFQ LLYVGDALWH EEAVLTTMDI THDGFGFMLA FGDMAWVPFT YSLQAQFLLH HPQPLGLPMA SVICLINATG YYIFRGANSQ KNTFRKNPSD PRVAGLETIS TATGRKLLVS GWWGMVRHPN YLGDLIMALA WSLPCGVSHL LPYFYLLYFT ALLVHREARD ERQCLQKYGL AWQEYCRRVP YRIMPYIY. It is sometimes possible for the material contained within the vial of "Delta (14)-sterol reductase (TM7SF2), Recombinant Protein" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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