Western Blot (WB)
(Western Blot analysis of Mouse liver tissue using TM7SF2 Polyclonal Antibody at dilution of 1:400)
Rabbit anti-Human, Mouse TM7SF2 Polyclonal Antibody | anti-TM7SF2 antibody
TM7SF2 Polyclonal Antibody
Gene Names
TM7SF2; ANG1; NET47; DHCR14A
Reactivity
Human, Mouse
Applications
ELISA, Western Blot
Purity
Affinity purification
Synonyms
TM7SF2; Polyclonal Antibody; TM7SF2 Polyclonal Antibody; ANG1; NET47; DHCR14A; anti-TM7SF2 antibody
Host
Rabbit
Reactivity
Human, Mouse
Clonality
Polyclonal
Isotype
IgG
Purity/Purification
Affinity purification
Form/Format
PBS with 0.05% sodium azide and 50% glycerol, PH7.4
Sequence Length
391
Applicable Applications for anti-TM7SF2 antibody
ELISA (EIA), Western Blot (WB)
Application Notes
WB: 1:500-1:2000
Immunogen
Synthetic peptide of human TM7SF2
Note
Centrifuge before opening to ensure complete recovery of vial contents.
Preparation and Storage
Store at -20 degree C. Avoid freeze / thaw cycles.
Western Blot (WB)
(Western Blot analysis of Mouse liver tissue using TM7SF2 Polyclonal Antibody at dilution of 1:400)
Western Blot (WB)
(Western Blot analysis of Mouse liver tissue using TM7SF2 Polyclonal Antibody at dilution of 1:400)
Immunohistochemistry (IHC)
(Immunohistochemistry of paraffin-embedded Human thyroid cancer using TM7SF2 Polyclonal Antibody at dilution of 1:25)
Immunohistochemistry (IHC)
(Immunohistochemistry of paraffin-embedded Human thyroid cancer using TM7SF2 Polyclonal Antibody at dilution of 1:25)
Related Product Information for anti-TM7SF2 antibody
Transmembrane 7 superfamily member 2 (TM7SF2, Sterol C14-reductase, 3beta-hydroxysterol Delta-reductase) is a 418 amino acid gene product that belongs to the ERG4/ERG24 family. TM7SF2 is a seven pass transmembrane protein that can localize to the membrane of the endoplasmic reticulum. TM7SF2 is involved in the conversion of lanosterol to cholesterol and, specifically, catalyzes the NADPH dependant reduction of 4,4-dimethyl-5-alphacholesta-8,14,24-trien-3-beta-ol to 4,4-dimethyl-5-alphacholesta-8,24-dien-3-beta-ol and NADP+.
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
Molecular Weight
Calculated MW: 46 kDa
NCBI Official Full Name
TM7SF2 protein
NCBI Official Synonym Full Names
transmembrane 7 superfamily member 2
NCBI Official Symbol
TM7SF2
NCBI Official Synonym Symbols
ANG1; NET47; DHCR14A
NCBI Protein Information
delta(14)-sterol reductase; delta(14)-sterol reductase; C-14 sterol reductase; another new gene 1 protein; delta-14-SR; putative sterol reductase SR-1; sterol C14-reductase
UniProt Protein Name
Delta(14)-sterol reductase
UniProt Gene Name
TM7SF2
UniProt Synonym Gene Names
ANG1; Delta-14-SR
UniProt Entry Name
ERG24_HUMAN
Uniprot Description
TM7SF2: Involved in the conversion of lanosterol to cholesterol. Belongs to the ERG4/ERG24 family. 2 isoforms of the human protein are produced by alternative splicing.
Protein type: Membrane protein, integral; Lipid Metabolism - steroid biosynthesis; EC 1.3.1.70; Oxidoreductase; Membrane protein, multi-pass; Endoplasmic reticulum
Chromosomal Location of Human Ortholog: 11q13
Cellular Component: endoplasmic reticulum membrane; integral to plasma membrane; endoplasmic reticulum; receptor complex
Molecular Function: delta14-sterol reductase activity
Biological Process: cholesterol biosynthetic process
Research Articles on TM7SF2
Similar Products
Product Notes
The TM7SF2 tm7sf2 (Catalog #AAA2517759) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The TM7SF2 Polyclonal Antibody reacts with Human, Mouse and may cross-react with other species as described in the data sheet. AAA Biotech's TM7SF2 can be used in a range of immunoassay formats including, but not limited to, ELISA (EIA), Western Blot (WB). WB: 1:500-1:2000. Researchers should empirically determine the suitability of the TM7SF2 tm7sf2 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "TM7SF2, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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