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Quality Control (Western blot analysis of immunized recombinant protein, using anti-BRRN1 monoclonal antibody. )

Mouse anti-Human BRRN1 Monoclonal Antibody | anti-BRRN1 antibody

Mouse monoclonal antibody Anti-Human BRRN1

Gene Names
NCAPH; BRRN1; CAP-H
Reactivity
Human
Applications
Dot Blot
Synonyms
BRRN1; Monoclonal Antibody; Mouse monoclonal antibody Anti-Human BRRN1; Homo sapiens non-SMC condensin I complex; subunit H (NCAPH); mRNA.; CAP-H; HCAP-H; anti-BRRN1 antibody
Ordering
For Research Use Only!
Host
Mouse
Reactivity
Human
Clonality
Monoclonal
Isotype
IgG1
Clone Number
2094C4_2a
Concentration
100 ug/ml (1.0 ml) (varies by lot)
Sequence Length
6059
Applicable Applications for anti-BRRN1 antibody
Dot Blot (DB)
Preparation
This antibody was purified using protein G column chromatography from culture supernatant of hybridoma cultured in a medium containing bovine IgG-depleted (approximately 95%) fetal bovine serum.
Sterility
Filtered through a 0.22 um membrane.

Quality Control

(Western blot analysis of immunized recombinant protein, using anti-BRRN1 monoclonal antibody. )

Quality Control (Western blot analysis of immunized recombinant protein, using anti-BRRN1 monoclonal antibody. )

Quality Control #2

(Arrow indicates the region of immunized recombinant protein carrying 50-200 amino acids.)

Quality Control #2 (Arrow indicates the region of immunized recombinant protein carrying 50-200 amino acids.)
Related Product Information for anti-BRRN1 antibody
This gene encodes a member of the barr gene family and a regulatory subunit of the condensin complex. This complex is required for the conversion of interphase chromatin into condensed chromosomes. The protein encoded by this gene is associated with mitotic chromosomes, except during the early phase of chromosome condensation. During interphase, the protein has a distinct punctate nucleolar localization. [provided by RefSeq][NCBI Entrez Gene Summary]

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
Molecular Weight
67,495 Da
NCBI Official Full Name
Homo sapiens non-SMC condensin I complex, subunit H (NCAPH), transcript variant 1, mRNA
NCBI Official Synonym Full Names
non-SMC condensin I complex, subunit H
NCBI Official Symbol
NCAPH
NCBI Official Synonym Symbols
BRRN1; CAP-H
NCBI Protein Information
condensin complex subunit 2; barren homolog 1; chromosome-associated protein H
UniProt Protein Name
Condensin complex subunit 2
UniProt Gene Name
NCAPH
UniProt Entry Name
CND2_HUMAN

NCBI Description

This gene encodes a member of the barr gene family and a regulatory subunit of the condensin complex. This complex is required for the conversion of interphase chromatin into condensed chromosomes. The protein encoded by this gene is associated with mitotic chromosomes, except during the early phase of chromosome condensation. During interphase, the protein has a distinct punctate nucleolar localization. Alternatively spliced transcript variants encoding different proteins have been described. [provided by RefSeq, Jul 2013]

Uniprot Description

NCAPH: Regulatory subunit of the condensin complex, a complex required for conversion of interphase chromatin into mitotic-like condense chromosomes. The condensin complex probably introduces positive supercoils into relaxed DNA in the presence of type I topoisomerases and converts nicked DNA into positive knotted forms in the presence of type II topoisomerases. Belongs to the CND2 (condensin subunit 2) family.

Protein type: Cell cycle regulation

Chromosomal Location of Human Ortholog: 2q11.2

Cellular Component: membrane; cytoplasm; condensin complex; nucleus; cytosol

Molecular Function: protein binding

Biological Process: cell division; mitotic chromosome condensation; mitotic cell cycle

Research Articles on BRRN1

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Product Notes

The BRRN1 ncaph (Catalog #AAA120479) is an Antibody produced from Mouse and is intended for research purposes only. The product is available for immediate purchase. The Mouse monoclonal antibody Anti-Human BRRN1 reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's BRRN1 can be used in a range of immunoassay formats including, but not limited to, Dot Blot (DB). Researchers should empirically determine the suitability of the BRRN1 ncaph for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "BRRN1, Monoclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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