Protein transport protein Sec24D (SEC24D) Recombinant Protein | SEC24D recombinant protein

Recombinant Human Protein transport protein Sec24D (SEC24D) , partial

• Gene Names: SEC24D; CLCRP2
• Purity: Greater or equal to 85% purity as determined by SDS-PAGE.
• Synonyms: Protein transport protein Sec24D (SEC24D); Recombinant Human Protein transport protein Sec24D (SEC24D); partial; SEC24D recombinant protein

• Host: E Coli or Yeast or Baculovirus or Mammalian Cell
• Purity/Purification: Greater or equal to 85% purity as determined by SDS-PAGE.
• Form/Format: Lyophilized or liquid (Format to be determined during the manufacturing process)
• Sequence Length: 1,033

• Species: Human
• Preparation and Storage: Store at -20 degrees C. For long-term storage, store at -20 degrees C or -80 degrees C. Store working aliquots at 4 degrees C for up to one week. Repeated freezing and thawing is not recommended.

Related Product Information for SEC24D recombinant protein

This protein is a member of the SEC24 subfamily of the SEC23
SEC24 family, which is involved in vesicle trafficking. The encoded protein has similarity to yeast Sec24p component of COPII. COPII is the coat protein complex responsible for vesicle budding from the ER. This gene product is implicated in the shaping of the vesicle, and also in cargo selection and concentration.

NCBI and Uniprot Product Information

• NCBI GI #: 968121920
• NCBI GeneID: 9871
• NCBI Accession #: NP_001304995.1
• NCBI GenBank Nucleotide #: NM_001318066.1
• UniProt Accession #: O94855; Q8IYI7
• Molecular Weight: 113,081 Da
• NCBI Official Full Name: protein transport protein Sec24D isoform 2
• NCBI Official Synonym Full Names: SEC24 homolog D, COPII coat complex component
• NCBI Official Symbol: SEC24D
• NCBI Official Synonym Symbols: CLCRP2
• NCBI Protein Information: protein transport protein Sec24D
• UniProt Protein Name: Protein transport protein Sec24D
• Protein Family: Protein transport protein
• UniProt Gene Name: SEC24D

NCBI Description

The protein encoded by this gene is a member of the SEC24 subfamily of the SEC23/SEC24 family, which is involved in vesicle trafficking. The encoded protein has similarity to yeast Sec24p component of COPII. COPII is the coat protein complex responsible for vesicle budding from the ER. This gene product is implicated in the shaping of the vesicle, and also in cargo selection and concentration. Mutations in this gene have been associated with Cole-Carpenter syndrome, a disorder affecting bone formation, resulting in craniofacial malformations and bones that break easily. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Dec 2015]

Uniprot Description

Component of the coat protein complex II (COPII) which promotes the formation of transport vesicles from the endoplasmic reticulum (ER). The coat has two main functions, the physical deformation of the endoplasmic reticulum membrane into vesicles and the selection of cargo molecules for their transport to the Golgi complex (PubMed:17499046, PubMed:20427317, PubMed:18843296). Plays a central role in cargo selection within the COPII complex and together with SEC24C may have a different specificity compared to SEC24A and SEC24B (PubMed:17499046, PubMed:20427317, PubMed:18843296). May more specifically package GPI-anchored proteins through the cargo receptor TMED10 (PubMed:20427317). May also be specific for IxM motif-containing cargos like the SNAREs GOSR2 and STX5 (PubMed:18843296).