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SDS-PAGE

Pandinus imperator Pandinin-2 Recombinant Protein | Pin2 recombinant protein

Recombinant Pandinus imperator Pandinin-2

Purity
Greater or equal to 85% purity as determined by SDS-PAGE.
Synonyms
Pandinus imperator Pandinin-2; Recombinant Pandinus imperator Pandinin-2; Non-disulfide-bridged peptide 3.1; NDBP-3.1; Non-disulfide-bridged peptide 4.1; NDBP-4.1; Pin2 recombinant protein
Ordering
For Research Use Only!
Host
E Coli or Yeast or Baculovirus or Mammalian Cell
Purity/Purification
Greater or equal to 85% purity as determined by SDS-PAGE.
Form/Format
Lyophilized or liquid (Format to be determined during the manufacturing process)
Sequence Positions
1-24aa; Cytoplasmic domain
Sequence
FWGALAKGAL KLIPSLFSSF SKKD
Sequence Length
24
Species
Pandinus imperator (Emperor scorpion)
Preparation and Storage
Store at -20 degree C, for extended storage, conserve at -20 degree C or -80 degree C.

SDS-PAGE

SDS-PAGE
Related Product Information for Pin2 recombinant protein
Disrupts cell membranes through formation of pores. Has strong antimicrobial activity against Gram-positive bacteria B. subtilis, S. epidermidis, E. faecalis and S. aureus. Is less active against Gram-negative bacteria P. aeruginosa and E Coli. Also increases efficacy of antibiotics (ampicillin, chloramphenicol, streptomycin, kanamycin, novobiocin) when tested against E Coli, probably by facilitating their incorporation into the bacteria. Possesses antifungal activity against C. albicans and hemolytic activity against human, sheep and pig erythrocytes.
References
"Characterization of unique amphipathic antimicrobial peptides from venom of the scorpion Pandinus imperator." Corzo G., Escoubas P., Villegas E., Barnham K.J., He W., Norton R.S., Nakajima T. Biochem. J. 359:35-45(2001)

NCBI and Uniprot Product Information

NCBI GI #
UniProt Accession #
Molecular Weight
4.6 kDa
NCBI Official Full Name
Pandinin-2
UniProt Protein Name
Pandinin-2
Protein Family
UniProt Gene Name
NDBP-4.1
UniProt Synonym Gene Names
NDBP-4.1
UniProt Entry Name
NDB31_PANIM

Uniprot Description

Disrupts cell membranes through formation of pores. Has strong antimicrobial activity against Gram-positive bacteria B.subtilis, S.epidermidis, E.faecalis and S.aureus. Is less active against Gram-negative bacteria P.aeruginosa and E.coli. Also increases efficacy of antibiotics (ampicillin, chloramphenicol, streptomycin, kanamycin, novobiocin) when tested against E.coli, probably by facilitating their incorporation into the bacteria. Possesses antifungal activity against C.albicans and hemolytic activity against human, sheep and pig erythrocytes.

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Product Notes

The Pin2 ndbp-4.1 (Catalog #AAA1177262) is a Recombinant Protein produced from E Coli or Yeast or Baculovirus or Mammalian Cell and is intended for research purposes only. The product is available for immediate purchase. The immunogen sequence is 1-24aa; Cytoplasmic domain. The amino acid sequence is listed below: FWGALAKGAL KLIPSLFSSF SKKD. It is sometimes possible for the material contained within the vial of "Pandinus imperator Pandinin-2, Recombinant Protein" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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