Heat-stable enterotoxin A3/A4 (sta3) Recombinant Protein | sta3 recombinant protein
Recombinant Heat-stable enterotoxin A3/A4 (sta3)
Purity
Greater or equal to 85% purity as determined by SDS-PAGE.
Synonyms
Heat-stable enterotoxin A3/A4 (sta3); Recombinant Heat-stable enterotoxin A3/A4 (sta3); Heat-stable enterotoxin A3/A4; ST-H ST-IB STA3/STA4 INN= Linaclotide; sta3 recombinant protein
Host
E Coli or Yeast or Baculovirus or Mammalian Cell
Purity/Purification
Greater or equal to 85% purity as determined by SDS-PAGE.
Form/Format
Lyophilized or liquid (Format to be determined during the manufacturing process)
Sequence Positions
54-72aa; Cytoplasmic domain
Sequence
NSSNYCCELCCNPACTG CY
Species
Escherichia coli
Preparation and Storage
Store at -20 degree C. For extended storage, store at -20 or -80 degree C.
NCBI and Uniprot Product Information
NCBI GI #
Molecular Weight
7,909 Da
NCBI Official Full Name
Heat-stable enterotoxin A3/A4
UniProt Protein Name
Heat-stable enterotoxin A3/A4
Protein Family
UniProt Gene Name
sta3
UniProt Synonym Gene Names
sta4
UniProt Entry Name
HST3_ECOLX
Uniprot Description
Function: Toxin which activates the particulate form of guanylate cyclase and increases cyclic GMP levels within the host intestinal epithelial cells.
Subcellular location: Secreted.
Pharmaceutical use: Linaclotide is under clinical trial by Microbia to be used to improve bowel function in patients with chronic constipation. Linaclotide corresponds to residues 59 to 72 with Tyr-62.
Sequence similarities: Belongs to the heat-stable enterotoxin family.
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Product Notes
The Heat-stable enterotoxin A3/A4 (sta3) sta3 (Catalog #AAA1173450) is a Recombinant Protein produced from E Coli or Yeast or Baculovirus or Mammalian Cell and is intended for research purposes only. The product is available for immediate purchase. The immunogen sequence is 54-72aa; Cytoplasmic domain. The amino acid sequence is listed below: NSSNYCCELC CNPACTG CY. It is sometimes possible for the material contained within the vial of "Heat-stable enterotoxin A3/A4 (sta3), Recombinant Protein" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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