L-cystine transport system permease protein tcyM (tcyM) Recombinant Protein | tcyM recombinant protein
Recombinant Bacillus subtilis L-cystine transport system permease protein tcyM (tcyM)
NCBI and Uniprot Product Information
Uniprot Description
Function: Part of the ABC transporter complex TcyJKLMN involved in L-cystine import. Probably responsible for the translocation of the substrate across the membrane
Probable. Is also involved in cystathionine, djenkolate, and S-methylcysteine transport. Ref.4
Subunit structure: The complex is composed of two ATP-binding proteins (TcyN), two transmembrane proteins (TcyL and TcyM) and two solute-binding proteins (TcyJ and TcyK)
Probable.
Subcellular location: Cell membrane; Multi-pass membrane protein
Potential.
Induction: More strongly expressed in the presence of methionine than in the presence of sulfate. Ref.3
Sequence similarities: Belongs to the binding-protein-dependent transport system permease family.Contains 1 ABC transmembrane type-1 domain.
Biophysicochemical propertiesKinetic parameters:KM=2.5 µM for L-cystine Ref.4Vmax=0.5 nmol/min/mg enzyme for L-cystine transport
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Product Notes
The tcyM tcym (Catalog #AAA1172592) is a Recombinant Protein produced from E Coli or Yeast or Baculovirus or Mammalian Cell and is intended for research purposes only. The product is available for immediate purchase. The immunogen sequence is 1-235. The amino acid sequence is listed below: MQFDFPFIVS AMKEMVKTIP LTLMMAVLPI VFGFLVALGN IIVRIFRIKG LVACSRFYVS FFRSTPAILH IMLIYLGIPP VADQVSSFFH LGWSANEIPV SMFVIMALSL TAGAYLTEII RSGILAMDTG QVEAAYSIGL TYSQTFRRVI LPQALKVSIP NFTNLGIGFL HTTSIAAIVA VPEITGTATI VASDNYAFLE AFIGAAIIYW VLTLILESAN GVLERKAARF QGGTL. It is sometimes possible for the material contained within the vial of "L-cystine transport system permease protein tcyM (tcyM), Recombinant Protein" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
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