CTD kinase subunit gamma (CTK3) Recombinant Protein | CTK3 recombinant protein
Recombinant Saccharomyces cerevisiae CTD kinase subunit gamma (CTK3)
NCBI and Uniprot Product Information
Uniprot Description
Gamma subunit of the CTDK-I complex, which hyperphosphorylates the C-terminal heptapeptide repeat domain (CTD) of the largest RNA polymerase II subunit. CTDK-I phosphorylates 'Ser-5' if the CTD substrate is not phosphorylated at 'Ser-5', but will phosphorylate 'Ser-2' of a CTD substrate if 'Ser-5' is already phosphorylated. CTDK-I is also more reactive toward substrates that are prephosphorylated at 'Ser-2' or 'Ser-5' compared with an unphosphorylated CTD substrate, therefore efficiently creating doubly phosphorylated CTD repeats. Involved in RNA polymerase I transcription and RNA polymerase II transcriptional elongation, and as part of the CTDK-I complex, pre-mRNA 3'-end processing and SET2 mediated H3K36 methylation. Together with CTK2, required for CTK1 CTD kinase activation. Required for DNA damage induced transcription. Involved in the adaptation to alternative carbon sources, including galactose, glycerol and ethanol, but not raffinose. Required for the integrity of the rDNA locus.
Similar Products
Product Notes
The CTK3 ctk3 (Catalog #AAA1143040) is a Recombinant Protein produced from E Coli or Yeast or Baculovirus or Mammalian Cell and is intended for research purposes only. The product is available for immediate purchase. The immunogen sequence is 1-296, full length protein. The amino acid sequence is listed below: MDSLEARLQF IQVLKNLQKT LHKTRDSITS SSTTTPPSSQ QKLNNDPIQF YLRNYRHHYE DFHQCLFDTT MKMDPLDRLD VVIYYVRIIR NLYPHSHSNT NVTKVLNEVL LMDIDLVFEL CLPCQDWKSL TNQATCKELF LDLSKLIHYD ATSVTHTPSD TTLIDATTWY SVKTERTTKD YKESLQRTES LLKDRDLKKL AFFQQFNSDT TAINPDLQTQ PTNANILLHR MEADRELHKR SKETSWYIER PSNDILDESE FKSLWTHFET TDSGFDKDDY KNIKALNDIA KASYIY. It is sometimes possible for the material contained within the vial of "CTD kinase subunit gamma (CTK3), Recombinant Protein" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
If you are ready to order, navigate to Shopping Cart and get ready to checkout.
