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Deubiquitinase and deneddylase Dub1 (cdu1) Recombinant Protein | CTL0247 recombinant protein

Recombinant Chlamydia trachomatis serovar L2 Deubiquitinase and deneddylase Dub1 (cdu1)

Purity
Greater or equal to 85% purity as determined by SDS-PAGE.
Synonyms
Deubiquitinase and deneddylase Dub1 (cdu1); Recombinant Chlamydia trachomatis serovar L2 Deubiquitinase and deneddylase Dub1 (cdu1); Recombinant Deubiquitinase and deneddylase Dub1 (cdu1); Deubiquitinase and deneddylase Dub1; ChlaDub1 EC= 3.4.22.-; CTL0247 recombinant protein
Ordering
Host
E Coli or Yeast or Baculovirus or Mammalian Cell
Purity/Purification
Greater or equal to 85% purity as determined by SDS-PAGE.
Form/Format
Lyophilized or liquid (Format to be determined during the manufacturing process)
Sequence Positions
1-401
Sequence
MLSPTNSTSKTAPVPPRDSSKPVLISEEPRNQLLQKVARTALAVLLVVVTLGLILLFYSFSDLQSFPWCCQTHPSTKEQPTISIPVPLPSPPLAVPRPSTPPPPVISRPSTPSAPKPSTPPPLLPKAPKPVKTQEDLLPLVPEQVFVEMYEDMARRQTIEALVPAWDSDIIFKCLCYFHTLYPGLIPLETFPPATIFNFKQKIISILEDKKAVLRGEPIKGPLPICCSKENYRRHLQRTTLLPVFMWYHPTPKTLSDTMQTMKQLAIKGSVGASHWLLVIVDIQARRLVYFDSLYNYVMPPENMKKELQSFAQQLDQVYPAYDSKKFSVKIAAKEVIQRGSGSSCGAWCCQFLHWYLKDPLTDALNDLPVDSVERHENLASFVQACEAAVQDLPELSWPEA
Sequence Length
401
Species
Chlamydia trachomatis serovar L2 (strain 434/Bu / ATCC VR-902B)
Preparation and Storage
Store at -20 degree C. For extended storage, store at -20 or -80 degree C.

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
Molecular Weight
44,977 Da
NCBI Official Full Name
hypothetical protein CTL0247
NCBI Official Symbol
CTL0247
NCBI Protein Information
hypothetical protein
UniProt Protein Name
Deubiquitinase and deneddylase Dub1
UniProt Gene Name
cdu1
UniProt Synonym Gene Names
ChlaDub1
UniProt Entry Name
CDUB1_CHLT2

Uniprot Description

Function: Effector proteins function to alter host cell physiology and promote bacterial survival in host tissues. This protease possesses deubiquitinating and deneddylating activities

By similarity. Impairs ubiquitination and degradation of NF-kappa-B inhibitor alpha (NFKBIA), thereby preventing NF-kappa-B activation. Ref.2

Subunit structure: Binds to host NFKBIA. Ref.2

Subcellular location: Secreted. Host cell. Membrane; Single-pass membrane protein. Note: Secreted, and delivered into the host cell. Located predominantly on the plasma membrane and to a lesser extent on intracellular membranes, especially the host cell nuclear envelope. Ref.2

Induction: Expressed late in the infectious cycle. Ref.2

Sequence similarities: Belongs to the peptidase C48 family.

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Product Notes

The CTL0247 cdu1 (Catalog #AAA1114864) is a Recombinant Protein produced from E Coli or Yeast or Baculovirus or Mammalian Cell and is intended for research purposes only. The product is available for immediate purchase. The immunogen sequence is 1-401. The amino acid sequence is listed below: MLSPTNSTSK TAPVPPRDSS KPVLISEEPR NQLLQKVART ALAVLLVVVT LGLILLFYSF SDLQSFPWCC QTHPSTKEQP TISIPVPLPS PPLAVPRPST PPPPVISRPS TPSAPKPSTP PPLLPKAPKP VKTQEDLLPL VPEQVFVEMY EDMARRQTIE ALVPAWDSDI IFKCLCYFHT LYPGLIPLET FPPATIFNFK QKIISILEDK KAVLRGEPIK GPLPICCSKE NYRRHLQRTT LLPVFMWYHP TPKTLSDTMQ TMKQLAIKGS VGASHWLLVI VDIQARRLVY FDSLYNYVMP PENMKKELQS FAQQLDQVYP AYDSKKFSVK IAAKEVIQRG SGSSCGAWCC QFLHWYLKDP LTDALNDLPV DSVERHENLA SFVQACEAAV QDLPELSWPE A. It is sometimes possible for the material contained within the vial of "Deubiquitinase and deneddylase Dub1 (cdu1), Recombinant Protein" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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