Integrin alpha pat-2 (pat-2) Recombinant Protein | pat-2 recombinant protein
Recombinant Caenorhabditis elegans Integrin alpha pat-2 (pat-2), partial
NCBI and Uniprot Product Information
Uniprot Description
Required for muscle development probably through the regulation of the actin-myosin cytoskeleton (PubMed:8106547, PubMed:12915588). During the formation of neuromuscular junctions at the larval stage, negatively regulates membrane protrusion from body wall muscles, probably through lamins such as epi-1, lam-2 and unc-52 (PubMed:16495308). Required for distal tip cell migration and dorsal pathfinding (PubMed:17606640). Required for egg-laying (PubMed:12915588). May play a role in cell motility and cell-cell interactions (). Plays a role in vulval development (PubMed:28135265). Probably within the alpha pat-2/beta pat-3 integrin receptor complex, plays a role in the negative regulation of let-23 signaling and vulval induction. This is probably partly by restricting the mobility of the let-23 receptor on the plasma membrane of vulval cells which thereby attenuates let-23 signaling (PubMed:28135265).
Research Articles on pat-2
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Product Notes
The pat-2 pat-2 (Catalog #AAA1105370) is a Recombinant Protein produced from E Coli or Yeast or Baculovirus or Mammalian Cell and is intended for research purposes only. The product is available for immediate purchase. It is sometimes possible for the material contained within the vial of "Integrin alpha pat-2 (pat-2), Recombinant Protein" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
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