Bifunctional lycopene cyclase/phytoene synthase (al-2) Recombinant Protein | NCU00585 recombinant protein
Recombinant Neurospora crassa Bifunctional lycopene cyclase/phytoene synthase (al-2)
NCBI and Uniprot Product Information
Uniprot Description
Function: Bifunctional enzyme that catalyzes the reactions from geranylgeranyl diphosphate to phytoene (phytoene synthase) and from lycopene to beta-carotene via the intermediate gamma-carotene and from 3,4-didehydrolycopene to torulene (lycopene cyclase). Torulene is further processed to the acidic carotenoid neurosporaxanthin. The cyclase preferentially catalyzes single cyclizations at only one end of the substrate to produce monocyclic carotenoids. Ref.4 Ref.5
Catalytic activity: Carotenoid psi-end group = carotenoid beta-end group.2 geranylgeranyl diphosphate = phytoene + 2 diphosphate.
Pathway: Carotenoid biosynthesis; beta-carotene biosynthesis.Carotenoid biosynthesis; phytoene biosynthesis; all-trans-phytoene from geranylgeranyl diphosphate: step 1/1.
Subcellular location: Membrane; Multi-pass membrane protein
Potential.
Induction: By blue light.
Sequence similarities: In the N-terminal section; belongs to the lycopene beta-cyclase family.In the C-terminal section; belongs to the phytoene/squalene synthase family.
Sequence caution: The sequence EAA36489.2 differs from that shown. Reason: Erroneous gene model prediction.
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Product Notes
The NCU00585 al-2 (Catalog #AAA1060128) is a Recombinant Protein produced from E Coli or Yeast or Baculovirus or Mammalian Cell and is intended for research purposes only. The product is available for immediate purchase. The immunogen sequence is 1-602. The amino acid sequence is listed below: MYDYAFVHLK FTVPAAVLLT AIAYPILNRI HLIQTGFLVV VAFTAALPWD AYLIKHKVWS YPPEAIVGPR LLGIPFEELF FFVIQTYITA LVYILFNKPV LHALHLNNQQ NPPAWMRVVK VTGQVVLVAL SVWGWNAAQV HQETSYLGLI LVWACPFLLA IWTLAGRFIL SLPWYATVLP MFLPTFYLWA VDEFALHRGT WSIGSGTKLD FCLFGKLDIE EATFFLVTNM LIVGGMAAFD QYLAVIYAFP TLFPKVNRYP TTHMLLQSRL INTSRYDLER IEGLREAVER LRLKSRSFYL ANSLFSGRLR IDLILLYSFC RLADDLVDDA KSRREVLSWT AKLNHFLDLH YKDADATEDP KKKAERIDAY IKTAFPPCAY QALHLLPTHI LPPKPLYDLI KGFEMDSQFT FHGTSDSTDL QYPIADDKDL ENYAIYVAGT VGELCIALII YHCLPDMSDT QKRELETAAC RMGIALQYVN IARDIVVDAR IGRVYLPTTW LKKEGLTHKM VLENPEGPEV IERMRRRLLE NAFELYGGAR PEMQRIPSEA RGPMIGAVEN YMAIGRVLRE RKEGTVFVRM EGRATVPKRR RLSTLLRALY EQ. It is sometimes possible for the material contained within the vial of "Bifunctional lycopene cyclase/phytoene synthase (al-2), Recombinant Protein" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
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