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Leukocyte immunoglobulin-like receptor subfamily B member 5 (LILRB5) Recombinant Protein | LILRB5 recombinant protein

Recombinant Human Leukocyte immunoglobulin-like receptor subfamily B member 5 (LILRB5)

Gene Names
LILRB5; LIR8; CD85C; LIR-8
Purity
Greater or equal to 85% purity as determined by SDS-PAGE.
Synonyms
Leukocyte immunoglobulin-like receptor subfamily B member 5 (LILRB5); Recombinant Human Leukocyte immunoglobulin-like receptor subfamily B member 5 (LILRB5); Leukocyte immunoglobulin-like receptor subfamily B member 5; CD85 antigen-like family member C; Leukocyte immunoglobulin-like receptor 8; LIR-8; CD_antigen=; CD85c; LILRB5 recombinant protein
Ordering
Host
E Coli or Yeast or Baculovirus or Mammalian Cell
Purity/Purification
Greater or equal to 85% purity as determined by SDS-PAGE.
Form/Format
Lyophilized or liquid (Format to be determined during the manufacturing process)
Sequence Positions
24-458
Sequence
GTLPKPT LWAEPASVIA RGKPVTLWCQ GPLETEEYRL DKEGLPWARK RQNPLEPGAK AKFHIPSTVY DSAGRYRCYY ETPAGWSEPS DPLELVATGF YAEPTLLALP SPVVASGGNV TLQCDTLDGL LTFVLVEEEQ KLPRTLYSQK LPKGPSQALF PVGPVTPSCR WRFRCYYYYR KNPQVWSNPS DLLEILVPGV SRKPSLLIPQ GSVVARGGSL TLQCRSDVGY DIFVLYKEGE HDLVQGSGQQ PQAGLSQANF TLGPVSRSHG GQYRCYGAHN LSPRWSAPSD PLDILIAGLI PDIPALSVQP GPKVASGENV TLLCQSWHQI DTFFLTKEGA AHPPLCLKSK YQSYRHQAEF SMSPVTSAQG GTYRCYSAIR SYPYLLSSPS YPQELVVSGP SGDPSLSPTG STPTPGPEDQ PLTPTGLDPQ SGLGRHLG
Sequence Length
435
Species
Homo sapiens (Human)
Preparation and Storage
Store at -20 degrees C. For long-term storage, store at -20 degrees C or -80 degrees C. Store working aliquots at 4 degrees C for up to one week. Repeated freezing and thawing is not recommended.

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
Molecular Weight
64,197 Da
NCBI Official Full Name
leukocyte immunoglobulin-like receptor subfamily B member 5 isoform 1
NCBI Official Synonym Full Names
leukocyte immunoglobulin-like receptor, subfamily B (with TM and ITIM domains), member 5
NCBI Official Symbol
LILRB5
NCBI Official Synonym Symbols
LIR8; CD85C; LIR-8
NCBI Protein Information
leukocyte immunoglobulin-like receptor subfamily B member 5; CD85 antigen-like family member C; leukocyte immunoglobulin-like receptor 8
UniProt Protein Name
Leukocyte immunoglobulin-like receptor subfamily B member 5
UniProt Gene Name
LILRB5
UniProt Synonym Gene Names
LIR8; LIR-8
UniProt Entry Name
LIRB5_HUMAN

NCBI Description

This gene is a member of the leukocyte immunoglobulin-like receptor (LIR) family, which is found in a gene cluster at chromosomal region 19q13.4. The encoded protein belongs to the subfamily B class of LIR receptors which contain two or four extracellular immunoglobulin domains, a transmembrane domain, and two to four cytoplasmic immunoreceptor tyrosine-based inhibitory motifs (ITIMs). Several other LIR subfamily B receptors are expressed on immune cells where they bind to MHC class I molecules on antigen-presenting cells and inhibit stimulation of an immune response. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]

Uniprot Description

LILRB5: May act as receptor for class I MHC antigens. 3 isoforms of the human protein are produced by alternative splicing.

Protein type: Membrane protein, integral; Immunoglobulin superfamily

Chromosomal Location of Human Ortholog: 19q13.4

Cellular Component: integral to membrane

Molecular Function: transmembrane receptor activity

Biological Process: cell surface receptor linked signal transduction; immune system process; defense response

Research Articles on LILRB5

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Product Notes

The LILRB5 lilrb5 (Catalog #AAA1060053) is a Recombinant Protein produced from E Coli or Yeast or Baculovirus or Mammalian Cell and is intended for research purposes only. The product is available for immediate purchase. The immunogen sequence is 24-458. The amino acid sequence is listed below: GTLPKPT LWAEPASVIA RGKPVTLWCQ GPLETEEYRL DKEGLPWARK RQNPLEPGAK AKFHIPSTVY DSAGRYRCYY ETPAGWSEPS DPLELVATGF YAEPTLLALP SPVVASGGNV TLQCDTLDGL LTFVLVEEEQ KLPRTLYSQK LPKGPSQALF PVGPVTPSCR WRFRCYYYYR KNPQVWSNPS DLLEILVPGV SRKPSLLIPQ GSVVARGGSL TLQCRSDVGY DIFVLYKEGE HDLVQGSGQQ PQAGLSQANF TLGPVSRSHG GQYRCYGAHN LSPRWSAPSD PLDILIAGLI PDIPALSVQP GPKVASGENV TLLCQSWHQI DTFFLTKEGA AHPPLCLKSK YQSYRHQAEF SMSPVTSAQG GTYRCYSAIR SYPYLLSSPS YPQELVVSGP SGDPSLSPTG STPTPGPEDQ PLTPTGLDPQ SGLGRHLG. It is sometimes possible for the material contained within the vial of "Leukocyte immunoglobulin-like receptor subfamily B member 5 (LILRB5), Recombinant Protein" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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