Signal transduction histidine-protein kinase BaeS (baeS) Recombinant Protein | baeS recombinant protein
Recombinant Escherichia coli Signal transduction histidine-protein kinase BaeS (baeS)
NCBI and Uniprot Product Information
NCBI Description
Confers novobiocin and deoxycholate resistance via activation of mdtABCD and acrD transcription. [More information is available at EcoGene: EG11617]. BaeS is the sensor kinase protein of the two-component BaeSR signal transduction system . [More information is available at EcoCyc: EG11617].
Uniprot Description
Function: Member of the two-component regulatory system BaeS/BaeR. Activates BaeR by phosphorylation which then activates the mdtABCD and probably the casABCDE-ygbT-ygbF operons. Ref.5
Catalytic activity: ATP + protein L-histidine = ADP + protein N-phospho-L-histidine.
Subcellular location: Cell inner membrane; Multi-pass membrane protein Ref.6.
Post-translational modification: Autophosphorylated. Ref.5
Disruption phenotype: Loss of induction of the casABCDE-ygbT-ygbF operon. Ref.7
Sequence similarities: Contains 1 HAMP domain.Contains 1 histidine kinase domain.
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Product Notes
The baeS baes (Catalog #AAA1058316) is a Recombinant Protein produced from E Coli or Yeast or Baculovirus or Mammalian Cell and is intended for research purposes only. The product is available for immediate purchase. The immunogen sequence is 1-467. The amino acid sequence is listed below: MKFWRPGITG KLFLAIFATC IVLLISMHWA VRISFERGFI DYIKHGNEQR LQLLSDALGE QYAQHGNWRF LRNNDRFVFQ ILRSFEHDNS EDKPGPGMPP HGWRTQFWVV DQNNKVLVGP RAPIPPDGTR RPILVNGAEV GAVIASPVER LTRNTDINFD KQQRQTSWLI VALATLLAAL ATFLLARGLL APVKRLVDGT HKLAAGDFTT RVTPTSEDEL GKLAQDFNQL ASTLEKNQQM RRDFMADISH ELRTPLAVLR GELEAIQDGV RKFTPETVAS LQAEVGTLTK LVDDLHQLSM SDEGALAYQK APVDLIPLLE VAGGAFRERF ASRGLKLQFS LPDSITVFGD RDRLMQLFNN LLENSLRYTD SGGSLQISAG QRDKTVRLTF ADSAPGVSDD QLQKLFERFY RTEGSRNRAS GGSGLGLAIC LNIVEAHNGR IIAAHSPFGG VSITVELPLE RDLQREV. It is sometimes possible for the material contained within the vial of "Signal transduction histidine-protein kinase BaeS (baeS), Recombinant Protein" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
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