Selenoprotein S (SELS) Recombinant Protein | VIMP recombinant protein
Recombinant Pig Selenoprotein S (SELS)
NCBI and Uniprot Product Information
Uniprot Description
Function: Involved in the degradation process of misfolded endoplasmic reticulum (ER) luminal proteins. Participates in the transfer of misfolded proteins from the ER to the cytosol, where they are destroyed by the proteasome in a ubiquitin-dependent manner. Probably acts by serving as a linker between DERL1, which mediates the retrotranslocation of misfolded proteins into the cytosol, and the ATPase complex VCP, which mediates the translocation and ubiquitination
By similarity. UniProtKB Q9BQE4
Subunit structure: Interacts with DERL1 and VCP, suggesting that it forms a membrane complex with DERL1 that serves as a receptor for VCP
By similarity. UniProtKB Q9BQE4
Subcellular location: Cytoplasm. Endoplasmic reticulum membrane; Single-pass membrane protein
By similarity Ref.1 UniProtKB Q9BQE4.
Tissue specificity: Ubiquitously expressed. Highest expression in liver and lung, with lower levels detected in spleen, kidney, brain, lymph nodes, small intestine, stomach and heart. Very low expression detected in longissimus dorsi. Ref.1
Sequence similarities: Belongs to the selenoprotein S family.
Sequence caution: The sequence CU467921 differs from that shown. Reason: Erroneous termination at position 189. Translated as Sec.
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Product Notes
The VIMP vimp (Catalog #AAA1058024) is a Recombinant Protein produced from E Coli or Yeast or Baculovirus or Mammalian Cell and is intended for research purposes only. The product is available for immediate purchase. The immunogen sequence is 1-190. The amino acid sequence is listed below: MEQDGDQLSA RPALETEGLR FLHVTVGSLL ATYGWYIVFC CILLYVVFQK LSTRLRALRQ RHLDGAAAAL EPDVVVKRQE ALAAARLKMQ EELNAQVEKH KEKLRQLEEE KRRQKIERWD SVQEGRSYRG DARKRQEEDS PGPSTSSVIP KRKSDKKPLR GGGYNPLSGE GGGACSWRPG RRGPSSGGUG. It is sometimes possible for the material contained within the vial of "Selenoprotein S (SELS), Recombinant Protein" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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