Protein translocase subunit SecY (secY) Recombinant Protein | MTH26 recombinant protein
Recombinant Methanothermobacter thermautotrophicus Protein translocase subunit SecY (secY)
NCBI and Uniprot Product Information
Uniprot Description
Function: The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently
By similarity. HAMAP-Rule MF_01465
Subunit structure: Component of the Sec protein translocase complex. Heterotrimer consisting of alpha (SecY), beta (SecG) and gamma (SecE) subunits. The heterotrimers can form oligomers, although 1 heterotrimer is thought to be able to translocate proteins. Interacts with the ribosome. May interact with SecDF, and other proteins may be involved
By similarity.
Subcellular location: Cell membrane; Multi-pass membrane protein HAMAP-Rule MF_01465.
Sequence similarities: Belongs to the SecY/SEC61-alpha family.
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Product Notes
The MTH26 secy (Catalog #AAA1035043) is a Recombinant Protein produced from E Coli or Yeast or Baculovirus or Mammalian Cell and is intended for research purposes only. The product is available for immediate purchase. The immunogen sequence is 1-456. The amino acid sequence is listed below: MEQLKEKFEP LFSVLPQVKS PGYRVPFREK LKWTGIILVL YFFLAQIPLY GLSANAVDQF AQFRAVLAGN FGSILTLGIG PIVSASIILQ LLVGGKILKL DLSRHEDKAF FQGLQKLLAI VFTFFEALIF VLTGSLAPSA PQFVWVLILQ LTIGGILIIF LDEVVSKWGF GSGVGLFIAA GVSQEIIVGA FNPLSAPTQP GVPAGRITGF LYLLFTGQSP DFQYYVLPVL ALIAVFLVVV YAESMRVEIP ISMGGGKRLS RGAVGKYPLR FIYASNMPVI LTSALLLNVQ LLANVFQKLG YPILGTVSNG QAVDGLAYLL TAPRSIDALI LDPFRVVFYA VVFIGLCVLF AWLWVEISNI GPRHVARQLY QMGMQIPGFR SSRGQFEKIL KRYIPTITIL GGAFVGLLAF VADLTGSLGG GTGVLLTVGI VYRLYEEIAQ EQLMDMHPIL RSFLGD. It is sometimes possible for the material contained within the vial of "Protein translocase subunit SecY (secY), Recombinant Protein" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
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