ATP-dependent zinc metalloprotease FtsH (ftsH) Recombinant Protein | HP1069 recombinant protein
Recombinant Helicobacter pylori ATP-dependent zinc metalloprotease FtsH (ftsH)
NCBI and Uniprot Product Information
Uniprot Description
Function: Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
By similarity. HAMAP-Rule MF_01458
Cofactor: Binds 1 zinc ion per subunit
By similarity. HAMAP-Rule MF_01458
Subunit structure: Homohexamer
Potential.
Subcellular location: Cell inner membrane; Multi-pass membrane protein; Cytoplasmic side
Probable Ref.1.
Disruption phenotype: A homozygous disruption strain was not identified, suggesting this gene may be essential. Ref.1
Sequence similarities: In the central section; belongs to the AAA ATPase family.In the C-terminal section; belongs to the peptidase M41 family.
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Product Notes
The HP1069 ftsh (Catalog #AAA1021079) is a Recombinant Protein produced from E Coli or Yeast or Baculovirus or Mammalian Cell and is intended for research purposes only. The product is available for immediate purchase. The immunogen sequence is 1-632. The amino acid sequence is listed below: MKPTNEPKKP FFQSPIILAV LGGILLIFFL RSFNSDGSFS DNFLASSTKN VSYHEIKQLI SNNEVENVSI GQTLIKASHK EGNNRVIYIA KRVPDLTLVP LLDEKKINYS GFSESNFFTD MLGWLMPILV ILGLWMFMAN RMQKNMGGGI FGMGSAKKLI NAEKPNVRFN DMAGNEEAKE EVVEIVDFLK YPERYANLGA KIPKGVLLVG PPGTGKTLLA KAVAGEAHVP FFSMGGSSFI EMFVGLGASR VRDLFETAKK QAPSIIFIDE IDAIGKSRAA GGVVSGNDER EQTLNQLLAE MDGFGSENAP VIVLAATNRP EILDPALMRP GRFDRQVLVD KPDFNGRVEI LKVHIKGVKL ANDVNLQEVA KLTAGLAGAD LANIINEAAL LAGRNNQKEV RQQHLKEAVE RGIAGLEKKS RRISPKEKKI VAYHESGHAV ISEMTKGSAR VNKVSIIPRG MAALGYTLNT PEENKYLMQK HELIAEIDVL LGGRAAEDVF LEEISTGASN DLERATDIIK GMVSYYGMSS VSGLMVLEKQ RNAFLGGGYG SSREFSEKTA EEMDLFIKNL LEERYKHVKQ TLSDYREAIE IMVKELFDKE VITGERVREI ISEYEVANNL ESRLIPLEEQ AS. It is sometimes possible for the material contained within the vial of "ATP-dependent zinc metalloprotease FtsH (ftsH), Recombinant Protein" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
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