Transcription initiation factor IIA subunit 1 (TfIIA-L) Recombinant Protein | TfIIA-L recombinant protein
Recombinant Drosophila melanogaster Transcription initiation factor IIA subunit 1 (TfIIA-L)
NCBI and Uniprot Product Information
Uniprot Description
Function: TFIIA is a component of the transcription machinery of RNA polymerase II and plays an important role in transcriptional activation. TFIIA in a complex with TBP mediates transcriptional activity.
Subunit structure: Belongs to the TFIID complex which is composed of TATA binding protein (Tbp) and a number of TBP-associated factors (Tafs). TFIIA is a heterodimer of a unprocessed large subunit 1 and a small subunit gamma. It was originally believed to be a heterotrimer of an alpha (p30), a beta (p20) and a gamma subunit (p14). Interacts with Tbp. Taf4 interacts with TFIIA-L when TFIIA-L is in complex with Tbp. Ref.1
Subcellular location: Nucleus.
Post-translational modification: The precursor form (48 kDa) is cleaved to give rise to the alpha (30 kDa) and beta (20 kDa) subunits. Ref.1
Sequence similarities: Belongs to the TFIIA subunit 1 family.
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Product Notes
The TfIIA-L tfiia-l (Catalog #AAA1002911) is a Recombinant Protein produced from E Coli or Yeast or Baculovirus or Mammalian Cell and is intended for research purposes only. The product is available for immediate purchase. The immunogen sequence is 263-366aa; full length protein. The amino acid sequence is listed below: DSSDEDESEE SDDNIDNDDD DDLDKDDDED AEHEDAAEEE PLNSEDDVTD EDSAEMFDTD NVIVCQYDKI TRSRNKWKFY LKDGIMNMRG KDYVFQKSNG DAEW. It is sometimes possible for the material contained within the vial of "Transcription initiation factor IIA subunit 1 (TfIIA-L), Recombinant Protein" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
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