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Leukocyte immunoglobulin-like receptor subfamily B member 3 (LILRB3) Recombinant Protein | LILRB3 recombinant protein

Recombinant Human Leukocyte immunoglobulin-like receptor subfamily B member 3 (LILRB3)

Purity
Greater or equal to 85% purity as determined by SDS-PAGE.
Synonyms
Leukocyte immunoglobulin-like receptor subfamily B member 3 (LILRB3); Recombinant Human Leukocyte immunoglobulin-like receptor subfamily B member 3 (LILRB3); Leukocyte immunoglobulin-like receptor subfamily B member 3; LIR-3; Leukocyte immunoglobulin-like receptor 3; CD85 antigen-like family member A; Immunoglobulin-like transcript 5; ILT-5; Monocyte inhibitory receptor HL9; CD_antigen=; CD85a; LILRB3 recombinant protein
Ordering
Host
E Coli or Yeast or Baculovirus or Mammalian Cell
Purity/Purification
Greater or equal to 85% purity as determined by SDS-PAGE.
Form/Format
Lyophilized or liquid (Format to be determined during the manufacturing process)
Sequence Positions
24-443
Sequence
GPFPKPT LWAEPGSVIS WGSPVTIWCQ GSQEAQEYRL HKEGSPEPLD RNNPLEPKNK ARFSIPSMTE HHAGRYRCHY YSSAGWSEPS DPLEMVMTGA YSKPTLSALP SPVVASGGNM TLRCGSQKGY HHFVLMKEGE HQLPRTLDSQ QLHSRGFQAL FPVGPVTPSH RWRFTCYYYY TNTPWVWSHP SDPLEILPSG VSRKPSLLTL QGPVLAPGQS LTLQCGSDVG YNRFVLYKEG ERDFLQRPGQ QPQAGLSQAN FTLGPVSPSN GGQYRCYGAH NLSSEWSAPS DPLNILMAGQ IYDTVSLSAQ PGPTVASGEN VTLLCQSWWQ FDTFLLTKEG AAHPPLRLRS MYGAHKYQAE FPMSPVTSAH AGTYRCYGSY SSNPHLLSHP SEPLELVVSG HSGGSSLPPT GPPSTPGLGR YLE
Sequence Length
420
Species
Homo sapiens (Human)
Preparation and Storage
Store at -20 degrees C. For long-term storage, store at -20 degrees C or -80 degrees C. Store working aliquots at 4 degrees C for up to one week. Repeated freezing and thawing is not recommended.

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
Molecular Weight
69,514 Da
NCBI Official Full Name
leukocyte immunoglobulin-like receptor subfamily B member 3-like isoform X4
NCBI Official Symbol
LOC102725035
NCBI Protein Information
leukocyte immunoglobulin-like receptor subfamily B member 3-like
UniProt Protein Name
Leukocyte immunoglobulin-like receptor subfamily B member 3
UniProt Gene Name
LILRB3
UniProt Synonym Gene Names
ILT5; LIR3; LIR-3; Leukocyte immunoglobulin-like receptor 3; ILT-5
UniProt Entry Name
LIRB3_HUMAN

Uniprot Description

LILRB3: May act as receptor for class I MHC antigens. Becomes activated upon coligation of LILRB3 and immune receptors, such as FCGR2B and the B-cell receptor. Down-regulates antigen-induced B- cell activation by recruiting phosphatases to its immunoreceptor tyrosine-based inhibitor motifs (ITIM). 3 isoforms of the human protein are produced by alternative splicing.

Protein type: Membrane protein, integral; Receptor, misc.

Chromosomal Location of Human Ortholog: 19q13.4

Cellular Component: integral to plasma membrane

Molecular Function: protein binding; transmembrane receptor activity; receptor activity

Biological Process: negative regulation of osteoclast differentiation; cell surface receptor linked signal transduction; immune system process; defense response

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Product Notes

The LILRB3 lilrb3 (Catalog #AAA1001129) is a Recombinant Protein produced from E Coli or Yeast or Baculovirus or Mammalian Cell and is intended for research purposes only. The product is available for immediate purchase. The immunogen sequence is 24-443. The amino acid sequence is listed below: GPFPKPT LWAEPGSVIS WGSPVTIWCQ GSQEAQEYRL HKEGSPEPLD RNNPLEPKNK ARFSIPSMTE HHAGRYRCHY YSSAGWSEPS DPLEMVMTGA YSKPTLSALP SPVVASGGNM TLRCGSQKGY HHFVLMKEGE HQLPRTLDSQ QLHSRGFQAL FPVGPVTPSH RWRFTCYYYY TNTPWVWSHP SDPLEILPSG VSRKPSLLTL QGPVLAPGQS LTLQCGSDVG YNRFVLYKEG ERDFLQRPGQ QPQAGLSQAN FTLGPVSPSN GGQYRCYGAH NLSSEWSAPS DPLNILMAGQ IYDTVSLSAQ PGPTVASGEN VTLLCQSWWQ FDTFLLTKEG AAHPPLRLRS MYGAHKYQAE FPMSPVTSAH AGTYRCYGSY SSNPHLLSHP SEPLELVVSG HSGGSSLPPT GPPSTPGLGR YLE. It is sometimes possible for the material contained within the vial of "Leukocyte immunoglobulin-like receptor subfamily B member 3 (LILRB3), Recombinant Protein" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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