Serine/threonine-protein kinase US3 homolog (69) Recombinant Protein | ORF69 recombinant protein
Recombinant Equine herpesvirus 1 Serine/threonine-protein kinase US3 homolog (69)
Purity
Greater or equal to 85% purity as determined by SDS-PAGE.
Synonyms
Serine/threonine-protein kinase US3 homolog (69); Recombinant Equine herpesvirus 1 Serine/threonine-protein kinase US3 homolog (69); ORF69 recombinant protein
Host
E Coli or Yeast or Baculovirus or Mammalian Cell
Purity/Purification
Greater or equal to 85% purity as determined by SDS-PAGE.
Form/Format
Lyophilized or liquid (Format to be determined during the manufacturing process)
Sequence Positions
1-382, Full length protein
Sequence
MENKQCDHLTDWFSTTSDASESMDTTPPLPPPTPSVDPSYSGAAADEDLYSDISEGDLEYSDCDSASESDEDDDDCLIPSKEKAREVAASFGYTVIKTLTPGSEGRVMVATKDGQPEPVVLKIGQKGTTLIEAMMLRNVNHPSVIQMKDTLVSGAITCMVLPHYSSDLYTFLTKESRRIPIDQALIIEKQILEGLRYLHAQRIIHRDVKTENIFINSVDQVCIADFGAAQFPVVEPADLGLAGTVETNAPEVLARAKYNSKADIWSAGIVLFEMLAYPSTLFEDPPSTPEEYVKSCHSQLLKIISTLKINPEEFPRDPGSRLVRGYIEYSRLERKPYTRYPCFQRVNLHIDGEFLVHKMLAFNAAMRPSAEELLSYPMFAQL
Sequence Length
382
Species
Equine herpesvirus 1 (strain V592) (EHV-1) (Equine abortion virus)
Preparation and Storage
Store at -20 degrees C. For long-term storage, store at -20 degrees C or -80 degrees C. Store working aliquots at 4 degrees C for up to one week. Repeated freezing and thawing is not recommended.
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
Molecular Weight
42,543 Da
NCBI Official Full Name
serine/threonine protein kinase US3
NCBI Official Symbol
ORF69
NCBI Protein Information
tegument protein; phosphorylates nuclear egress lamina protein; mediates phosphorylation of HDAC1 and HDAC2 and other cellular and viral proteins
UniProt Protein Name
Serine/threonine-protein kinase US3 homolog
UniProt Gene Name
69
Uniprot Description
Multifunctional serine/threonine kinase that plays a role in several processes including egress of virus particles from the nucleus, modulation of the actin cytoskeleton and inhibition of apoptosis. Phosphorylates UL31 and UL34, two critical regulators of capsid budding from nucleus to endoplasmic reticulum, thereby facilitating virion egress. Modulates and redistributes host components of the nuclear envelope, including LMNA, emerin/EMD and the nuclear matrix protein MATR3. Phosphorylates envelope glycoprotein B (gB), probably to direct it to the cell surface. Promotes virus intracellular spread by restructuring host cell cytoskeleton. Blocks host apoptosis to extend cell survival and allow efficient viral replication. Promotes viral gene expression by phosphorylating host HDAC2 to reduce viral genome silencing ().
Research Articles on ORF69
Similar Products
Product Notes
The ORF69 69 (Catalog #AAA1246463) is a Recombinant Protein produced from E Coli or Yeast or Baculovirus or Mammalian Cell and is intended for research purposes only. The product is available for immediate purchase. The immunogen sequence is 1-382, Full length protein. The amino acid sequence is listed below: MENKQCDHLT DWFSTTSDAS ESMDTTPPLP PPTPSVDPSY SGAAADEDLY SDISEGDLEY SDCDSASESD EDDDDCLIPS KEKAREVAAS FGYTVIKTLT PGSEGRVMVA TKDGQPEPVV LKIGQKGTTL IEAMMLRNVN HPSVIQMKDT LVSGAITCMV LPHYSSDLYT FLTKESRRIP IDQALIIEKQ ILEGLRYLHA QRIIHRDVKT ENIFINSVDQ VCIADFGAAQ FPVVEPADLG LAGTVETNAP EVLARAKYNS KADIWSAGIV LFEMLAYPST LFEDPPSTPE EYVKSCHSQL LKIISTLKIN PEEFPRDPGS RLVRGYIEYS RLERKPYTRY PCFQRVNLHI DGEFLVHKML AFNAAMRPSA EELLSYPMFA QL. It is sometimes possible for the material contained within the vial of "Serine/threonine-protein kinase US3 homolog (69), Recombinant Protein" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
If you are ready to order, navigate to Shopping Cart and get ready to checkout.
