Zinc finger protein 423 (Znf423) Recombinant Protein | Znf423 recombinant protein

Recombinant Mouse Zinc finger protein 423 (Znf423) , partial

• Gene Names: Zfp423; Roaz; Ebfaz; nur12; Zfp104; Znf423; ataxia1; mKIAA0760
• Purity: Greater or equal to 85% purity as determined by SDS-PAGE.
• Synonyms: Zinc finger protein 423 (Znf423); Recombinant Mouse Zinc finger protein 423 (Znf423); partial; Znf423 recombinant protein

• Host: E Coli or Yeast or Baculovirus or Mammalian Cell
• Purity/Purification: Greater or equal to 85% purity as determined by SDS-PAGE.
• Form/Format: Lyophilized or liquid (Format to be determined during the manufacturing process)
• Sequence Length: 1,271

• Species: Mouse
• Preparation and Storage: Store at -20 degrees C. For long-term storage, store at -20 degrees C or -80 degrees C. Store working aliquots at 4 degrees C for up to one week. Repeated freezing and thawing is not recommended.

Related Product Information for Znf423 recombinant protein

This protein is a nuclear protein that belongs to the family of Kruppel-like C2H2 zinc finger proteins. It functions as a DNA-binding transcription factor by using distinct zinc fingers in different signaling pathways. Thus, it is thought that this gene may have multiple roles in signal transduction during development.

NCBI and Uniprot Product Information

• NCBI GI #: 46359077
• NCBI GeneID: 94187
• NCBI Accession #: NP_201584.2
• NCBI GenBank Nucleotide #: NM_033327.2
• UniProt Accession #: Q80TS5; Q6PCP2; Q6X497; Q8CIQ1; Q9ESD2; B2RSW4
• Molecular Weight: 143,090 Da
• NCBI Official Full Name: zinc finger protein 423 isoform 1
• NCBI Official Synonym Full Names: zinc finger protein 423
• NCBI Official Symbol: Zfp423
• NCBI Official Synonym Symbols: Roaz; Ebfaz; nur12; Zfp104; Znf423; ataxia1; mKIAA0760
• NCBI Protein Information: zinc finger protein 423
• UniProt Protein Name: Zinc finger protein 423
• Protein Family: Zinc finger protein
• UniProt Gene Name: Znf423
• UniProt Synonym Gene Names: Ebfaz; Kiaa0760; Nur12; Oaz; Zfp423

Uniprot Description

Transcription factor that can both act as an activator or a repressor depending on the context. Plays a central role in BMP signaling and olfactory neurogenesis. Associates with SMADs in response to BMP2 leading to activate transcription of BMP target genes. Acts as a transcriptional repressor via its interaction with EBF1, a transcription factor involved in terminal olfactory receptor neurons differentiation; this interaction preventing EBF1 to bind DNA and activate olfactory-specific genes. Involved in olfactory neurogenesis by participating in a developmental switch that regulates the transition from differentiation to maturation in olfactory receptor neurons. Controls proliferation and differentiation of neural precursors in cerebellar vermis formation.