Zinc finger RNA-binding protein (ZFR) Recombinant Protein | ZFR recombinant protein

Recombinant Human Zinc finger RNA-binding protein (ZFR) , partial

• Gene Names: ZFR; ZFR1; SPG71
• Purity: Greater or equal to 85% purity as determined by SDS-PAGE.
• Synonyms: Zinc finger RNA-binding protein (ZFR); Recombinant Human Zinc finger RNA-binding protein (ZFR); partial; ZFR recombinant protein

• Host: E Coli or Yeast or Baculovirus or Mammalian Cell
• Purity/Purification: Greater or equal to 85% purity as determined by SDS-PAGE.
• Form/Format: Lyophilized or liquid (Format to be determined during the manufacturing process)
• Sequence Length: 1074

• Species: Human
• Preparation and Storage: Store at -20 degrees C. For long-term storage, store at -20 degrees C or -80 degrees C. Store working aliquots at 4 degrees C for up to one week. Repeated freezing and thawing is not recommended.

NCBI and Uniprot Product Information

• NCBI GI #: 34101286
• NCBI GeneID: 51663
• NCBI Accession #: NP_057191.2
• NCBI GenBank Nucleotide #: NM_016107.4
• UniProt Accession #: Q96KR1; Q05C08; Q3B7X5; Q6P5A3; Q86UA0; Q9H6V4; Q9NTI1; Q9Y687; B2RNR5
• Molecular Weight: 117,012 Da
• NCBI Official Full Name: zinc finger RNA-binding protein
• NCBI Official Synonym Full Names: zinc finger RNA binding protein
• NCBI Official Symbol: ZFR
• NCBI Official Synonym Symbols: ZFR1; SPG71
• NCBI Protein Information: zinc finger RNA-binding protein
• UniProt Protein Name: Zinc finger RNA-binding protein
• Protein Family: Zinc finger RNA-binding protein
• UniProt Gene Name: ZFR
• UniProt Synonym Gene Names: hZFR

NCBI Description

This gene encodes an RNA-binding protein characterized by its DZF (domain associated with zinc fingers) domain. The encoded protein may play a role in the nucleocytoplasmic shuttling of another RNA-binding protein, Staufen homolog 2, in neurons. Expression of this gene is regulated through alternative polyadenylation that mediates differential microRNA targeting. Elevated expression of this gene has been observed in human patients with pancreatic cancer and knockdown of this gene may result in reduced viability and invasion of pancreatic cancer cells. [provided by RefSeq, Sep 2016]

Uniprot Description

Involved in postimplantation and gastrulation stages of development. Involved in the nucleocytoplasmic shuttling of STAU2. Binds to DNA and RNA ().