E3 ubiquitin-protein ligase ZFP91 (Zfp91) Recombinant Protein | Zfp91 recombinant protein

Recombinant Mouse E3 ubiquitin-protein ligase ZFP91 (Zfp91)

Cat. Num. AAA1297405

• Gene Names: Zfp91; Pzf; Zfp-91; AL024263; AW545902; 9130014I08Rik; A530054C17Rik
• Purity: Greater or equal to 85% purity as determined by SDS-PAGE.
• Synonyms: E3 ubiquitin-protein ligase ZFP91 (Zfp91); Recombinant Mouse E3 ubiquitin-protein ligase ZFP91 (Zfp91); Zfp91 recombinant protein

• Host: E Coli or Yeast or Baculovirus or Mammalian Cell
• Purity/Purification: Greater or equal to 85% purity as determined by SDS-PAGE.
• Form/Format: Lyophilized or liquid (Format to be determined during the manufacturing process)
• Sequence Positions: 2-572, Full length protein
• Sequence: PGETEEPRSPEQQDQEGGPAAAADAASEELRPGAAAAPAAPAETASSRVLRGGRDRGRTAAAAAAAAAAVSRRRKAEYPRRRRSSPSNRPPDGPGHQPAAAKPPSPAQGKKSPRLQCIEKLTTDKDPKEEKEDDSVLPQEVSITTTRASRSWRSSSRTSISRLRDSENTRSSRSKTGSLQLVCKTEPITDQLDYDVPEEHQSPGGISSDEEEEEEEEMLISEEEIPFKDDPRDETYKPHLERETPKPRRKSGKVKEEKEKKEIKVEVEVEVKEEENEIREDEEPPRKRGRRRKDDKSPRLPKRRKKPPIQYVRCEMEGCGTVLAHPRYLQHHIKYQHLLKKKYVCPHPSCGRLFRLQKQLLRHAKHHTDQRDYICEYCARAFKSSHNLAVHRMIHTGEKPLQCEICGFTCRQKASLNWHMKKHDADSFYQFSCNICGKKFEKKDSVVAHKAKSHPEVLIAEALAANAGALITSTDILGTNPEPLTQPADGQGLPLLPEPLGNSTAGECLLLEAEGMSKSYCSGTERVSLMADGKIFVGSGSSGGTEGLVMNSDILGATTEVLIEDTDSTGP
• Sequence Length: 571

• Species: Mouse
• Preparation and Storage: Store at -20 degrees C. For long-term storage, store at -20 degrees C or -80 degrees C. Store working aliquots at 4 degrees C for up to one week. Repeated freezing and thawing is not recommended.

Related Product Information for Zfp91 recombinant protein

This protein is a member of the zinc finger family of proteins. The gene product contains C2H2 type domains, which are the classical zinc finger domains found in numerous nucleic acid-binding proteins. A read-through transcript variant composed of ZFP91 and CNTF sequence has been identified, but it is thought to be non-coding. Read-through transcription of ZFP91 and CNTF has also been observed in mouse. A pseudogene has also been identified on chromosome 2.

NCBI and Uniprot Product Information

• NCBI GI #: 90669983
• NCBI GeneID: 109910
• NCBI Accession #: NP_443735.2
• NCBI GenBank Nucleotide #: NM_053009.3
• UniProt Accession #: Q62511; Q3TEQ3; Q3UH61; Q62509; Q6P219; Q6PG06; Q8BPY3; Q8C2B4; Q8CDZ3
• Molecular Weight: 51,539 Da
• NCBI Official Full Name: E3 ubiquitin-protein ligase ZFP91
• NCBI Official Synonym Full Names: zinc finger protein 91
• NCBI Official Symbol: Zfp91
• NCBI Official Synonym Symbols: Pzf; Zfp-91; AL024263; AW545902; 9130014I08Rik; A530054C17Rik
• NCBI Protein Information: E3 ubiquitin-protein ligase ZFP91
• UniProt Protein Name: E3 ubiquitin-protein ligase ZFP91
• Protein Family: E3 ubiquitin-protein ligase
• UniProt Gene Name: Zfp91
• UniProt Synonym Gene Names: Pzf; Zfp-91

NCBI Description

The protein encoded by this gene is a member of the zinc finger family of proteins. The gene product contains C2H2-type domains, which are the classical zinc finger domains found in numerous nucleic acid-binding proteins. The homologous human protein has been shown to function as a regulator of the non-canonical NF-kappaB pathway in lymphotoxin-beta receptor signaling. A read-through transcript variant composed of Zfp91 and the downstream Cntf gene sequence has been identified, but it is thought to be non-coding. Read-through transcription of Zfp91 and Cntf has been observed in both human and mouse. A Zfp91-related pseudogene has also been identified on chromosome 17. [provided by RefSeq, Oct 2010]

Uniprot Description

Atypical E3 ubiquitin-protein ligase that mediates 'Lys-63'-linked ubiquitination of MAP3K14/NIK, leading to stabilize and activate MAP3K14/NIK. It thereby acts as an activator of the non-canonical NF-kappa-B2/NFKB2 pathway. May also play an important role in cell proliferation and/or anti-apoptosis.