Nuclear-interacting partner of ALK (Zc3hc1) Recombinant Protein | Zc3hc1 recombinant protein
Recombinant Mouse Nuclear-interacting partner of ALK (Zc3hc1)
Gene Names
Zc3hc1; Nipa; HSPC216; AU018540; AU019789; 1110054L24Rik
Purity
Greater or equal to 85% purity as determined by SDS-PAGE.
Synonyms
Nuclear-interacting partner of ALK (Zc3hc1); Recombinant Mouse Nuclear-interacting partner of ALK (Zc3hc1); Zc3hc1 recombinant protein
Host
E Coli or Yeast or Baculovirus or Mammalian Cell
Purity/Purification
Greater or equal to 85% purity as determined by SDS-PAGE.
Form/Format
Lyophilized or liquid (Format to be determined during the manufacturing process)
Sequence Positions
2-501, Full length protein
Sequence
AATSEGPLFAASIEKTWGSVVRSPEGTPQKVRELIDEGIVPEEGGTEPKDTAATFQSVDGSPQAEQSPLESTSKEAFFHRVETFSSLKWAGKPPELSPLICAKYGWVTVECDMLKCSSCQAFLCASLQPTFDFGRYKERCAELKKSLCSAHEKFCFWPDSPSPDRFGMLPLGEPAVLISEFLDRFQSLCHLDLQLPSLRPEDLKTMCLTEDAVSALLHLLEDELDFHADDRKTTSKLGSDVQVQATACVLSLCGWACSSLEPTQLSLITCYQCMRKVGLWGFQQIESSMTDLEASFGLTSSPIPGVEGRPEHFPLVPESPRRMMTRSQDATVSPGSEQSEKSPGPIVSRTRSWESSSPVDRPELEAASPTTRSRPVTRSMGTGDSAGVEVPSSPLRRTKRARLCSSSSSDTSPRSFFDPTSQHRDWCPWVNITLVKETKENGETEVDACTPAEPGWKAVLTILLAHKRSNQPAETDSMSLSEKSRKVFRIFRQWESSSSS
Sequence Length
500
Species
Mouse
Preparation and Storage
Store at -20 degrees C. For long-term storage, store at -20 degrees C or -80 degrees C. Store working aliquots at 4 degrees C for up to one week. Repeated freezing and thawing is not recommended.
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
Molecular Weight
52,824 Da
NCBI Official Full Name
nuclear-interacting partner of ALK isoform 1
NCBI Official Synonym Full Names
zinc finger, C3HC type 1
NCBI Official Symbol
Zc3hc1
NCBI Official Synonym Symbols
Nipa; HSPC216; AU018540; AU019789; 1110054L24Rik
NCBI Protein Information
nuclear-interacting partner of ALK
UniProt Protein Name
Nuclear-interacting partner of ALK
Protein Family
UniProt Gene Name
Zc3hc1
UniProt Synonym Gene Names
Nipa; mNIPA
Uniprot Description
Essential component of a SCF-type E3 ligase complex, SCF(NIPA), a complex that controls mitotic entry by mediating ubiquitination and subsequent degradation of cyclin B1 (CCNB1). Its cell-cycle-dependent phosphorylation regulates the assembly of the SCF(NIPA) complex, restricting CCNB1 ubiquitination activity to interphase. Its inactivation results in nuclear accumulation of CCNB1 in interphase and premature mitotic entry (). Overexpression may be able to protect from apoptosis induced by IL-3 withdrawal.
Research Articles on Zc3hc1
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Product Notes
The Zc3hc1 zc3hc1 (Catalog #AAA1476437) is a Recombinant Protein produced from E Coli or Yeast or Baculovirus or Mammalian Cell and is intended for research purposes only. The product is available for immediate purchase. The immunogen sequence is 2-501, Full length protein. The amino acid sequence is listed below: AATSEGPLFA ASIEKTWGSV VRSPEGTPQK VRELIDEGIV PEEGGTEPKD TAATFQSVDG SPQAEQSPLE STSKEAFFHR VETFSSLKWA GKPPELSPLI CAKYGWVTVE CDMLKCSSCQ AFLCASLQPT FDFGRYKERC AELKKSLCSA HEKFCFWPDS PSPDRFGMLP LGEPAVLISE FLDRFQSLCH LDLQLPSLRP EDLKTMCLTE DAVSALLHLL EDELDFHADD RKTTSKLGSD VQVQATACVL SLCGWACSSL EPTQLSLITC YQCMRKVGLW GFQQIESSMT DLEASFGLTS SPIPGVEGRP EHFPLVPESP RRMMTRSQDA TVSPGSEQSE KSPGPIVSRT RSWESSSPVD RPELEAASPT TRSRPVTRSM GTGDSAGVEV PSSPLRRTKR ARLCSSSSSD TSPRSFFDPT SQHRDWCPWV NITLVKETKE NGETEVDACT PAEPGWKAVL TILLAHKRSN QPAETDSMSL SEKSRKVFRI FRQWESSSSS. It is sometimes possible for the material contained within the vial of "Nuclear-interacting partner of ALK (Zc3hc1), Recombinant Protein" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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