Human zinc finger and BTB domain containing 7B ELISA Kit | ZBTB7B elisa kit

Human Zinc finger and BTB domain-containing protein 7B, ZBTB7B ELISA Kit

Cat. Num. AAA9334418

• Gene Names: ZBTB7B; THPOK; ZFP67; ZBTB15; ZFP-67; c-KROX; hcKROX; ZNF857B
• Reactivity: Human
• Synonyms: zinc finger and BTB domain containing 7B; Human Zinc finger and BTB domain-containing protein 7B; ZBTB7B ELISA Kit; Human Zinc finger and BTB domain-containing protein 7B (ZBTB7B) ELISA kit; RP11-307C12.9; DKFZp686G01254; THPOK; ZBTB15; ZFP67; ZNF857B; c-Krox; hcKrox; OTTHUMP00000035545; kruppel-related zinc finger protein hcKrox; zinc finger and BTB domain containing 15; zinc finger prote; ZBTB7B elisa kit

• Reactivity: Human
• Specificity: No significant cross-reactivity or interference between this analyte and analogues is observed.

• Samples: Body fluids, tissue homogenates, secretions or feces samples
• Assay Type: Quantitative Sandwich
• Detection Range: 3.12 ng/ml - 100 ng/ml
• Sensitivity: 1.0 ng/ml.
• Intra-assay Precision: Intra-assay CV (%) is less than 15%
• Inter-assay Precision: Inter-assay CV (%) is less than 15%. [CV(%) = SD/mean ×100].
• Preparation and Storage: Store all reagents at 2-8 degree C

Related Product Information for ZBTB7B elisa kit

Background/Introduction: This Quantitative Sandwich ELISA kit is only for in vitro research use only! This kit is intended to be used for determination the level of ZBTB7B (hereafter termed "analyte") in undiluted original Human body fluids, tissue homogenates, secretions or feces samples. This kit is NOT suitable for assaying non-biological sources of substances.

NCBI and Uniprot Product Information

• NCBI GI #: 356995909
• NCBI GeneID: 51043
• NCBI Accession #: NP_001239335.1
• NCBI GenBank Nucleotide #: NM_001252406.2
• UniProt Accession #: O15156; Q68DR2; Q96EP2; B4E3K5; D3DV83; J3KQQ3
• Molecular Weight: 58,027 Da
• NCBI Official Full Name: zinc finger and BTB domain-containing protein 7B isoform 2
• NCBI Official Synonym Full Names: zinc finger and BTB domain containing 7B
• NCBI Official Symbol: ZBTB7B
• NCBI Official Synonym Symbols: THPOK; ZFP67; ZBTB15; ZFP-67; c-KROX; hcKROX; ZNF857B
• NCBI Protein Information: zinc finger and BTB domain-containing protein 7B; zinc finger protein 857B; zinc finger protein Th-POK; zinc finger protein 67 homolog; zinc finger and BTB domain containing 15; T-helper-inducing POZ/Krueppel-like factor; krueppel-related zinc finger protein cKrox
• UniProt Protein Name: Zinc finger and BTB domain-containing protein 7B
• Protein Family: Zinc finger and BTB domain-containing protein
• UniProt Gene Name: ZBTB7B
• UniProt Synonym Gene Names: ZBTB15; ZFP67; ZNF857B; hcKrox; Zfp-67
• UniProt Entry Name: ZBT7B_HUMAN

NCBI Description

This gene encodes a zinc finger-containing transcription factor that acts as a key regulator of lineage commitment of immature T-cell precursors. It is necessary and sufficient for commitment of CD4 lineage, while its absence causes CD8 commitment. It also functions as a transcriptional repressor of type I collagen genes. Alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Jan 2012]

Uniprot Description

ZBTB7B: Transcription regulator that acts as a key regulator of lineage commitment of immature T-cell precursors. Necessary and sufficient for commitment of CD4 lineage, while its absence causes CD8 commitment. Development of immature T-cell precursors (thymocytes) to either the CD4 helper or CD8 killer T-cell lineages correlates precisely with their T-cell receptor specificity for major histocompatibility complex class II or class I molecules, respectively. Transcriptional repressor of the collagen COL1A1 and COL1A2 genes. May also function as a repressor of fibronectin and possibly other extracellular matrix genes.

Protein type: C2H2-type zinc finger protein

Chromosomal Location of Human Ortholog: 1q21.3

Cellular Component: nucleoplasm; nucleus

Molecular Function: DNA binding; metal ion binding

Biological Process: transcription from RNA polymerase II promoter; regulation of transcription, DNA-dependent; multicellular organismal development; ectoderm development; cell differentiation