Zinc finger and BTB domain-containing protein 20 (ZBTB20) Recombinant Protein | ZBTB20 recombinant protein

Recombinant Human Zinc finger and BTB domain-containing protein 20 (ZBTB20)

Cat. Num. AAA1436700

• Gene Names: ZBTB20; HOF; DPZF; PRIMS; ODA-8S; ZNF288
• Purity: Greater or equal to 85% purity as determined by SDS-PAGE.
• Synonyms: Zinc finger and BTB domain-containing protein 20 (ZBTB20); Recombinant Human Zinc finger and BTB domain-containing protein 20 (ZBTB20); ZBTB20 recombinant protein

• Host: E Coli or Yeast or Baculovirus or Mammalian Cell
• Purity/Purification: Greater or equal to 85% purity as determined by SDS-PAGE.
• Form/Format: Lyophilized or liquid (Format to be determined during the manufacturing process)
• Sequence Positions: 1-741, Full length protein
• Sequence: MLERKKPKTAENQKASEENEITQPGGSSAKPGLPCLNFEAVLSPDPALIHSTHSLTNSHAHTGSSDCDISCKGMTERIHSINLHNFSNSVLETLNEQRNRGHFCDVTVRIHGSMLRAHRCVLAAGSPFFQDKLLLGYSDIEIPSVVSVQSVQKLIDFMYSGVLRVSQSEALQILTAASILQIKTVIDECTRIVSQNVGDVFPGIQDSGQDTPRGTPESGTSGQSSDTESGYLQSHPQHSVDRIYSALYACSMQNGSGERSFYSGAVVSHHETALGLPRDHHMEDPSWITRIHERSQQMERYLSTTPETTHCRKQPRPVRIQTLVGNIHIKQEMEDDYDYYGQQRVQILERNESEECTEDTDQAEGTESEPKGESFDSGVSSSIGTEPDSVEQQFGPGAARDSQAEPTQPEQAAEAPAEGGPQTNQLETGASSPERSNEVEMDSTVITVSNSSDKSVLQQPSVNTSIGQPLPSTQLYLRQTETLTSNLRMPLTLTSNTQVIGTAGNTYLPALFTTQPAGSGPKPFLFSLPQPLAGQQTQFVTVSQPGLSTFTAQLPAPQPLASSAGHSTASGQGEKKPYECTLCNKTFTAKQNYVKHMFVHTGEKPHQCSICWRSFSLKDYLIKHMVTHTGVRAYQCSICNKRFTQKSSLNVHMRLHRGEKSYECYICKKKFSHKTLLERHVALHSASNGTPPAGTPPGARAGPPGVVACTEGTTYVCSVCPAKFDQIEQFNDHMRMHVSDG
• Sequence Length: 741

• Species: Human
• Preparation and Storage: Store at -20 degrees C. For long-term storage, store at -20 degrees C or -80 degrees C. Store working aliquots at 4 degrees C for up to one week. Repeated freezing and thawing is not recommended.

NCBI and Uniprot Product Information

• NCBI GI #: 257900533
• NCBI GeneID: 26137
• NCBI Accession #: NP_001157814.1
• NCBI GenBank Nucleotide #: NM_001164342.2
• UniProt Accession #: Q9HC78; Q63HP6; Q8N6R5; Q9Y410
• Molecular Weight: 73,401 Da
• NCBI Official Full Name: zinc finger and BTB domain-containing protein 20 isoform 1
• NCBI Official Synonym Full Names: zinc finger and BTB domain containing 20
• NCBI Official Symbol: ZBTB20
• NCBI Official Synonym Symbols: HOF; DPZF; PRIMS; ODA-8S; ZNF288
• NCBI Protein Information: zinc finger and BTB domain-containing protein 20
• UniProt Protein Name: Zinc finger and BTB domain-containing protein 20
• Protein Family: Zinc finger and BTB domain-containing protein
• UniProt Gene Name: ZBTB20
• UniProt Synonym Gene Names: DPZF; ZNF288

NCBI Description

This gene, which was initially designated as dendritic cell-derived BTB/POZ zinc finger (DPZF), belongs to a family of transcription factors with an N-terminal BTB/POZ domain and a C-terminal DNA-bindng zinc finger domain. The BTB/POZ domain is a hydrophobic region of approximately 120 aa which mediates association with other BTB/POZ domain-containing proteins. This gene acts as a transcriptional repressor and plays a role in many processes including neurogenesis, glucose homeostasis, and postnatal growth. Mutations in this gene have been associated with Primrose syndrome as well as the 3q13.31 microdeletion syndrome. Alternative splicing results in multiple transcript variants encoding distinct isoforms. [provided by RefSeq, Feb 2017]

Uniprot Description

May be a transcription factor that may be involved in hematopoiesis, oncogenesis, and immune responses (PubMed:11352661). Plays a role in postnatal myogenesis, may be involved in the regulation of satellite cells self-renewal ().