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Probable multidrug resistance ABC transporter ATP-binding/permease protein YheH (yheH) Recombinant Protein | yheH recombinant protein

Recombinant Bacillus subtilis Probable multidrug resistance ABC transporter ATP-binding/permease protein YheH (yheH)

Purity
Greater or equal to 85% purity as determined by SDS-PAGE.
Synonyms
Probable multidrug resistance ABC transporter ATP-binding/permease protein YheH (yheH); Recombinant Bacillus subtilis Probable multidrug resistance ABC transporter ATP-binding/permease protein YheH (yheH); Recombinant Probable multidrug resistance ABC transporter ATP-binding/permease protein YheH (yheH); Probable multidrug resistance ABC transporter ATP-binding/permease protein YheH EC= 3.6.3.-; yheH recombinant protein
Ordering
Host
E Coli or Yeast or Baculovirus or Mammalian Cell
Purity/Purification
Greater or equal to 85% purity as determined by SDS-PAGE.
Form/Format
Lyophilized or liquid (Format to be determined during the manufacturing process)
Sequence Positions
1-673
Sequence
MKIGKTLWRYALLYRKLLITAVLLLTVAVGAELTGPFIGKKMIDDHILGIEKTWYEAAEKDKNAVQFHGVSYVREDRLQEPVSKAKEAHIYQVGMAFYFVDQAVSFDGNRTVSDGKLTITNGDKSRAYAAEKLTKQELFQFYQPEIKGMVLLICLYGGLLVFSVFFQYGQHYLLQMSANRIIQKMRQDVFSHIQKMPIRYFDNLPAGKVVARITNDTEAIRDLYVTVLSTFVTSGIYMFGIFTALFLLDVKLAFVCLAIVPIIWLWSVIYRRYASYYNQKIRSINSDINAKMNESIQGMTIIQAFRHQKETMREFEELNESHFYFQNRMLNLNSLMSHNLVNVIRNLAFVCLIWHFGGASLNAAGIVSIGVLYAFVDYLNRLFQPITGIVNQFSKLELARVSAGRVFELLEEKNTEEAGEPAKERALGRVEFRDVSFAYQEGEEVLKHISFTAQKGETVALVGHTGSGKSSILNLLFRFYDAQKGDVLIDGKSIYNMSRQELRSHMGIVLQDPYLFSGTIGSNVSLDDERMTEEEIKNALRQVGAEPLLKKLPKGINEPVIEKGSTLSSGERQLISFARALAFDPAILILDEATAHIDTETEAVIQKALDVVKQGRTTFVIAHRLSTIRNADQILVLDKGEIVERGNHEELMALEGQYYQMYELQKGQKHSIA
Sequence Length
673
Species
Bacillus subtilis (strain 168)
Preparation and Storage
Store at -20 degree C. For extended storage, store at -20 or -80 degree C.

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
Molecular Weight
76,305 Da
NCBI Official Full Name
ABC transporter ATP-binding protein
NCBI Official Symbol
yheH
NCBI Protein Information
ABC transporter ATP-binding protein
UniProt Protein Name
Probable multidrug resistance ABC transporter ATP-binding/permease protein YheH
UniProt Gene Name
yheH
UniProt Entry Name
YHEH_BACSU

Uniprot Description

Function: Involved in the transport of four structurally unrelated drugs, including doxorubicin and mitoxantrone. Transmembrane domains (TMD) form a pore in the membrane and the ATP-binding domain (NBD) is responsible for energy generation. Ref.4

Enzyme regulation: Inhibited by ortho-vanadate. Ref.4

Subunit structure: Heterodimer composed of YheH and YheI. Ref.4

Subcellular location: Cell membrane; Multi-pass membrane protein Ref.4.

Induction: Induced by several classes of structurally unrelated antibiotics, such as erythromycin, fusidic acid or linezolid. Ref.4

Miscellaneous: Overexpression reduces the sporulation efficiency possibly by modulating the function of KinA.

Sequence similarities: Belongs to the ABC transporter superfamily.Contains 1 ABC transmembrane type-1 domain.Contains 1 ABC transporter domain.

Research Articles on yheH

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Product Notes

The yheH yheh (Catalog #AAA1166784) is a Recombinant Protein produced from E Coli or Yeast or Baculovirus or Mammalian Cell and is intended for research purposes only. The product is available for immediate purchase. The immunogen sequence is 1-673. The amino acid sequence is listed below: MKIGKTLWRY ALLYRKLLIT AVLLLTVAVG AELTGPFIGK KMIDDHILGI EKTWYEAAEK DKNAVQFHGV SYVREDRLQE PVSKAKEAHI YQVGMAFYFV DQAVSFDGNR TVSDGKLTIT NGDKSRAYAA EKLTKQELFQ FYQPEIKGMV LLICLYGGLL VFSVFFQYGQ HYLLQMSANR IIQKMRQDVF SHIQKMPIRY FDNLPAGKVV ARITNDTEAI RDLYVTVLST FVTSGIYMFG IFTALFLLDV KLAFVCLAIV PIIWLWSVIY RRYASYYNQK IRSINSDINA KMNESIQGMT IIQAFRHQKE TMREFEELNE SHFYFQNRML NLNSLMSHNL VNVIRNLAFV CLIWHFGGAS LNAAGIVSIG VLYAFVDYLN RLFQPITGIV NQFSKLELAR VSAGRVFELL EEKNTEEAGE PAKERALGRV EFRDVSFAYQ EGEEVLKHIS FTAQKGETVA LVGHTGSGKS SILNLLFRFY DAQKGDVLID GKSIYNMSRQ ELRSHMGIVL QDPYLFSGTI GSNVSLDDER MTEEEIKNAL RQVGAEPLLK KLPKGINEPV IEKGSTLSSG ERQLISFARA LAFDPAILIL DEATAHIDTE TEAVIQKALD VVKQGRTTFV IAHRLSTIRN ADQILVLDKG EIVERGNHEE LMALEGQYYQ MYELQKGQKH SIA. It is sometimes possible for the material contained within the vial of "Probable multidrug resistance ABC transporter ATP-binding/permease protein YheH (yheH), Recombinant Protein" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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