XPNPEP2 recombinant protein
Recombinant Human XPNPEP2 Protein
Gene Names
XPNPEP2; APP2; AEACEI
Reactivity
Human
Applications
ELISA, Western Blot, SDS-Page
Purity
Greater than 95% as determined by SEC-HPLC and reducing SDS-PAGE.
Synonyms
XPNPEP2; Recombinant Human XPNPEP2 Protein; Xaa-Pro aminopeptidase 2; Aminoacylproline aminopeptidase; Membrane-bound aminopeptidase P; Membrane-bound APP; Membrane-bound AmP; mAmP; X-Pro aminopeptidase 2; XPNPEP2 recombinant protein
Host
Human cells
Reactivity
Human
Purity/Purification
Greater than 95% as determined by SEC-HPLC and reducing SDS-PAGE.
Form/Format
Supplied as a 0.2 muM filtered solution of 20mM Tris-HCl, 150mM NaCl, pH 8.0.
Sequence
HTKPVDLGGQ DVRNCSTNPP YLPVTVVNTT MSLTALRQQM QTQNLSAYII PGTDAHMNEY IGQHDERRAW ITGFTGSAGT AVVTMKKAAV WTDSRYWTQA ERQMDCNWEL HKEVGTTPIV TWLLTEIPAG GRVGFDPFLL SIDTWESYDL ALQGSNRQLV SITTNLVDLV WGSERPPVPN QPIYALQEAF TGSTWQEKVS GVRSQMQKHQ KVPTAVLLSA LEETAWLFNL RASDIPYNPF FYSYTLLTDS SIRLFANKSR FSSETLSYLN SSCTGPMCVQ IEDYSQVRDS IQAYSLGDVR IWIGTSYTMY GIYEMIPKEK LVTDTYSPVM MTKAVKNSKE QALLKASHVR DAVAVIRYLV WLEKNVPKGT VDEFSGAEIV DKFRGEEQFS SGPSFETISA SGLNAALAHY SPTKELNRKL SSDEMYLLDS GGQYWDGTTD ITRTVHWGTP SAFQKEAYTR VLIGNIDLSR LIFPAATSGR MVEAFARRAL WDAGLNYGHG TGHGIGNFLC VHEWPVGFQS NNIAMAKGMF TSIEPGYYKD GEFGIRLEDV ALVVEAKTKY PGSYLTFEVV SFVPYDRNLI DVSLLSPEHL QYLNRYYQTI REKVGPELQR RQLLEEFEWL QQHTEPLAAH HHHHH
Sequence Length
674
Applicable Applications for XPNPEP2 recombinant protein
ELISA (EIA),Western Blot (WB), SDS-PAGE, Mass Spectrometry (MS)
Endotoxin
Less than 0.1 ng/mug (1 IEU/mug) as determined by LAL test.
Directions for Use
Always centrifuge tubes before opening. Do not mix by vortex or pipetting. It is not recommended to reconstitute to a concentration less than 100 mug/ml. Dissolve the lyophilized protein in 1X PBS. Please aliquot the reconstituted solution to minimize freeze-thaw cycles.
Preparation and Storage
Lyophilized protein should be stored at -20 degree C, though stable at room temperature for 3 weeks. Reconstituted protein solution can be stored at 2-8 degree C for 2-7 days. Aliquots of reconstituted samples are stable at -20 degree C for 3 months.
Related Product Information for XPNPEP2 recombinant protein
Recombinant Human XPNPEP2 Protein is produced by our Mammalian expression system and the target gene encoding His22-Ala650 is expressed with a 6His tag at the C-terminus.
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
Molecular Weight
75,625 Da
NCBI Official Full Name
xaa-Pro aminopeptidase 2
NCBI Official Synonym Full Names
X-prolyl aminopeptidase 2
NCBI Official Symbol
XPNPEP2
NCBI Official Synonym Symbols
APP2; AEACEI
NCBI Protein Information
xaa-Pro aminopeptidase 2
UniProt Protein Name
Xaa-Pro aminopeptidase 2
UniProt Gene Name
XPNPEP2
UniProt Synonym Gene Names
Membrane-bound APP; Membrane-bound AmP; mAmP
UniProt Entry Name
XPP2_HUMAN
NCBI Description
Aminopeptidase P is a hydrolase specific for N-terminal imido bonds, which are common to several collagen degradation products, neuropeptides, vasoactive peptides, and cytokines. Structurally, the enzyme is a member of the 'pita bread fold' family and occurs in mammalian tissues in both soluble and GPI-anchored membrane-bound forms. A membrane-bound and soluble form of this enzyme have been identified as products of two separate genes. [provided by RefSeq, Jul 2008]
Uniprot Description
XPNPEP2: A metalloprotease that may play a role in the inflammatory process and other reactions produced in response to injury or infection. May also play a role in the metabolism of the vasodilator bradykinin. Belongs to the peptidase M24B family.
Protein type: EC 3.4.11.9; Membrane protein, GPI anchor; Protease
Chromosomal Location of Human Ortholog: Xq25
Cellular Component: membrane
Molecular Function: aminopeptidase activity
Disease: Angioedema Induced By Ace Inhibitors, Susceptibility To
Research Articles on XPNPEP2
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Product Notes
The XPNPEP2 xpnpep2 (Catalog #AAA8250032) is a Recombinant Protein produced from Human cells and is intended for research purposes only. The product is available for immediate purchase. The Recombinant Human XPNPEP2 Protein reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's XPNPEP2 can be used in a range of immunoassay formats including, but not limited to, ELISA (EIA),Western Blot (WB), SDS-PAGE, Mass Spectrometry (MS). Researchers should empirically determine the suitability of the XPNPEP2 xpnpep2 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. The amino acid sequence is listed below: HTKPVDLGGQ DVRNCSTNPP YLPVTVVNTT MSLTALRQQM QTQNLSAYII PGTDAHMNEY IGQHDERRAW ITGFTGSAGT AVVTMKKAAV WTDSRYWTQA ERQMDCNWEL HKEVGTTPIV TWLLTEIPAG GRVGFDPFLL SIDTWESYDL ALQGSNRQLV SITTNLVDLV WGSERPPVPN QPIYALQEAF TGSTWQEKVS GVRSQMQKHQ KVPTAVLLSA LEETAWLFNL RASDIPYNPF FYSYTLLTDS SIRLFANKSR FSSETLSYLN SSCTGPMCVQ IEDYSQVRDS IQAYSLGDVR IWIGTSYTMY GIYEMIPKEK LVTDTYSPVM MTKAVKNSKE QALLKASHVR DAVAVIRYLV WLEKNVPKGT VDEFSGAEIV DKFRGEEQFS SGPSFETISA SGLNAALAHY SPTKELNRKL SSDEMYLLDS GGQYWDGTTD ITRTVHWGTP SAFQKEAYTR VLIGNIDLSR LIFPAATSGR MVEAFARRAL WDAGLNYGHG TGHGIGNFLC VHEWPVGFQS NNIAMAKGMF TSIEPGYYKD GEFGIRLEDV ALVVEAKTKY PGSYLTFEVV SFVPYDRNLI DVSLLSPEHL QYLNRYYQTI REKVGPELQR RQLLEEFEWL QQHTEPLAAH HHHHH. It is sometimes possible for the material contained within the vial of "XPNPEP2, Recombinant Protein" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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