SDS-Page
Lymphotactin/XCL1 Recombinant Protein | XCL1 recombinant protein
Lymphotactin/XCL1, 22-114aa, Human, His tag, E Coli
Gene Names
XCL1; LTN; ATAC; LPTN; SCM1; SCM-1; SCM1A; SCYC1; SCM-1a
Applications
SDS-Page
Purity
> 90% by SDS-PAGE
Synonyms
Lymphotactin/XCL1; 22-114aa; Human; His tag; E Coli; Chemokine (C motif) ligand 1; XCL1; ATAC; LPTN; LTN; SCM-1; SCM-1a; SCM1; SCYC1; Chemokine (C motif) ligand 1 C motif chemokine 1; SCM 1 alpha; Chemokine C Motif Ligand 1; Small inducible cytokine C1; Small Inducible Cytokine Subfamily C Member 1; XC chemokine ligand 1; XCL1.; XCL1 recombinant protein
Host
E Coli
Purity/Purification
> 90% by SDS-PAGE
Form/Format
Liquid. In 20 mM Tris-HCl Buffer (pH 8.0) containing 30% glycerol 2 mM DTT, 0.2 M NaCl.
Concentration
0.25 mg/ml (determined by Bradford assay) (varies by lot)
Sequence
MGSSHHHHHH SSGLVPRGSH MVGSEVSDKR TCVSLTTQRL PVSRIKTYTI TEGSLRAVIF ITKRGLKVCA DPQATWVRDV VRSMDRKSNT RNNMIQTKPT GTQQSTNTAV TLTG
Sequence Length
114
Applicable Applications for XCL1 recombinant protein
SDS-PAGE
Antigen Species
Human
Tag Information
His-tag
Endotoxin
< 1 EU per 1ug of protein (determined by LAL method)
Preparation and Storage
Can be stored at 2°C to 8°C for a week. For long term storage, aliquot and store at -20°C to -80°C. Avoid repeated freezing and thawing cycles.
SDS-Page
SDS-Page
Related Product Information for XCL1 recombinant protein
Lymphotactin, also known as XCL1, is member of gamma or C subfamily of chemokines. It is found in high levels in spleen, thymus, intestine and peripheral blood leukocytes, and at lower levels in lung, prostate gland and ovary. The expression of lymphotactin is restricted to activated T cells such as activated CD8+ T cells and other calss IMHC restricted T cells. Since lymphotactin is produced by lymphocytes and acts on lymphocytes, it is speculated that it is a messenger in T cell chemoattraction. Recombinant human XCL1 protein, fused to His-tag at N-terminus, was expressed in E Coli and purified by using conventional chromatography.
Product Categories/Family for XCL1 recombinant protein
References
Yoshida T., et al. (1996). FEBS Lett. 395 (1):82-8.; Kennedy J., et al. (1995). J Immunol. 155 (1):203-9.;
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
Molecular Weight
12.5 kDa (114aa), confirmed by MALDI-TOF. (Molecular weight on SDS-PAGE will appear higher)
NCBI Official Full Name
lymphotactin
NCBI Official Synonym Full Names
X-C motif chemokine ligand 1
NCBI Official Symbol
XCL1
NCBI Official Synonym Symbols
LTN; ATAC; LPTN; SCM1; SCM-1; SCM1A; SCYC1; SCM-1a
NCBI Protein Information
lymphotactin
UniProt Protein Name
Lymphotactin
Protein Family
UniProt Gene Name
XCL1
UniProt Synonym Gene Names
LTN; SCYC1
NCBI Description
This antimicrobial gene encodes a member of the chemokine superfamily. Chemokines function in inflammatory and immunological responses, inducing leukocyte migration and activation. The encoded protein is a member of the C-chemokine subfamily, retaining only two of four cysteines conserved in other chemokines, and is thought to be specifically chemotactic for T cells. This gene and a closely related family member are located on the long arm of chromosome 1. [provided by RefSeq, Sep 2014]
Uniprot Description
Chemotactic activity for lymphocytes but not for monocytes or neutrophils. In thymus, mediates medullary accumulation of thymic dendritic cells and contributes to regulatoy T cell development, playing a role in self-tolerance establishment.
Research Articles on XCL1
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Product Notes
The XCL1 xcl1 (Catalog #AAA203317) is a Recombinant Protein produced from E Coli and is intended for research purposes only. The product is available for immediate purchase. The tag for this protein is His-tag. AAA Biotech's Lymphotactin/XCL1 can be used in a range of immunoassay formats including, but not limited to, SDS-PAGE. Researchers should empirically determine the suitability of the XCL1 xcl1 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. The amino acid sequence is listed below: MGSSHHHHHH SSGLVPRGSH MVGSEVSDKR TCVSLTTQRL PVSRIKTYTI TEGSLRAVIF ITKRGLKVCA DPQATWVRDV VRSMDRKSNT RNNMIQTKPT GTQQSTNTAV TLTG. It is sometimes possible for the material contained within the vial of "Lymphotactin/XCL1, Recombinant Protein" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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