Rabbit wingless-type MMTV integration site family, member 5A ELISA Kit | WNT5A elisa kit
Rabbit Protein Wnt-5a, WNT5A ELISA Kit
NCBI and Uniprot Product Information
Uniprot Description
Function: Ligand for members of the frizzled family of seven transmembrane receptors. Can activate or inhibit canonical Wnt signaling, depending on receptor context. In the presence of FZD4, activates beta-catenin signaling. In the presence of ROR2, inhibits the canonical Wnt pathway by promoting beta-catenin degradation through a GSK3-independent pathway which involves down-regulation of beta-catenin-induced reporter gene expression. Suppression of the canonical pathway allows chondrogenesis to occur and inhibits tumor formation. Stimulates cell migration. Decreases proliferation, migration, invasiveness and clonogenicity of carcinoma cells and may act as a tumor suppressor. Mediates motility of melanoma cells. Required during embryogenesis for extension of the primary anterior-posterior axis and for outgrowth of limbs and the genital tubercle Inhibits type II collagen expression in chondrocytes.By similarityManual assertion inferred from sequence similarityUniProtKB:P22725UniProtKB:P41221
Research Articles on WNT5A
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Product Notes
The Rabbit WNT5A wnt5a (Catalog #AAA9336251) is an ELISA Kit and is intended for research purposes only. The product is available for immediate purchase. The AAA9336251 ELISA Kit recognizes Rabbit WNT5A. It is sometimes possible for the material contained within the vial of "wingless-type MMTV integration site family, member 5A, ELISA Kit" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
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