Human WD repeat domain 5 ELISA Kit | WDR5 elisa kit

Human WD repeat-containing protein 5, WDR5 ELISA Kit

Cat. Num. AAA9341940

• Gene Names: WDR5; SWD3; BIG-3; CFAP89
• Reactivity: Human
• Synonyms: WD repeat domain 5; Human WD repeat-containing protein 5; WDR5 ELISA Kit; Human WD repeat-containing protein 5 (WDR5) ELISA kit; BIG-3; SWD3; BMP2-induced 3-kb gene protein; Set1c WD40 repeat protein; homolog; WD-repeat protein 5; WDR5 elisa kit

• Reactivity: Human
• Specificity: No significant cross-reactivity or interference between this analyte and analogues is observed.

• Samples: Body fluids, tissue homogenates, secretions or feces samples
• Assay Type: Quantitative Sandwich
• Detection Range: 3.12 ng/ml - 100 ng/ml
• Sensitivity: 1.0 ng/ml.
• Intra-assay Precision: Intra-assay CV (%) is less than 15%
• Inter-assay Precision: Inter-assay CV (%) is less than 15%. [CV(%) = SD/mean ×100].
• Preparation and Storage: Store all reagents at 2-8 degree C

Related Product Information for WDR5 elisa kit

Background/Introduction: This Quantitative Sandwich ELISA kit is only for in vitro research use only! This kit is intended to be used for determination the level of WDR5 (hereafter termed "analyte") in undiluted original Human body fluids, tissue homogenates, secretions or feces samples. This kit is NOT suitable for assaying non-biological sources of substances.

NCBI and Uniprot Product Information

• NCBI GI #: 16554627
• NCBI GeneID: 11091
• NCBI Accession #: NP_060058.1
• NCBI GenBank Nucleotide #: NM_017588.2
• UniProt Accession #: P61964; Q91VA5; Q9NWX7; Q9UGP9
• Molecular Weight: 36,588 Da
• NCBI Official Full Name: WD repeat-containing protein 5
• NCBI Official Synonym Full Names: WD repeat domain 5
• NCBI Official Symbol: WDR5
• NCBI Official Synonym Symbols: SWD3; BIG-3; CFAP89
• NCBI Protein Information: WD repeat-containing protein 5; WD-repeat protein 5; BMP2-induced 3-kb gene protein; SWD3, Set1c WD40 repeat protein, homolog; cilia and flagella associated protein 89
• UniProt Protein Name: WD repeat-containing protein 5
• Protein Family: WD repeat-containing protein
• UniProt Gene Name: WDR5
• UniProt Synonym Gene Names: BIG3
• UniProt Entry Name: WDR5_HUMAN

NCBI Description

This gene encodes a member of the WD repeat protein family. WD repeats are minimally conserved regions of approximately 40 amino acids typically bracketed by gly-his and trp-asp (GH-WD), which may facilitate formation of heterotrimeric or multiprotein complexes. Members of this family are involved in a variety of cellular processes, including cell cycle progression, signal transduction, apoptosis, and gene regulation. This protein contains 7 WD repeats. Alternatively spliced transcript variants encoding the same protein have been identified. [provided by RefSeq, Jul 2008]

Uniprot Description

WDR5: a WD40 repeat protein. May accelerate osteoblast differentiation. Interacts with HCFC1. WD40 repeats are found in a number of eukaryotic proteins that coordinate multi-protein complex assemblies. WD40 proteins are implicated in many functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly.

Protein type: Adaptor/scaffold

Chromosomal Location of Human Ortholog: 9q34

Cellular Component: nucleoplasm; histone methyltransferase complex; nucleus; histone acetyltransferase complex

Molecular Function: protein binding; histone lysine N-methyltransferase activity (H3-K4 specific); histone acetyltransferase activity (H4-K16 specific)

Biological Process: establishment and/or maintenance of chromatin architecture; transcription, DNA-dependent; histone H3-K4 methylation; skeletal development