Dolichyl-diphosphooligosaccharide--protein glycosyltransferase 48 kDa subunit (SPCC338.15) Recombinant Protein | wbp1 recombinant protein
Recombinant Schizosaccharomyces pombe Dolichyl-diphosphooligosaccharide--protein glycosyltransferase 48 kDa subunit (SPCC338.15)
NCBI and Uniprot Product Information
Uniprot Description
Function: Essential subunit of N-oligosaccharyl transferase enzyme which catalyzes the transfer of a high mannose oligosaccharide to an asparagine residue within an Asn-X-Ser/Thr consensus motif in nascent polypeptide chains. N-glycosylation occurs cotranslationally and the complex associates with the Sec61 complex at the channel-forming translocon complex that mediates protein translocation across the endoplasmic reticulum (ER)
By similarity. UniProtKB P33767
Catalytic activity: Dolichyl diphosphooligosaccharide + protein L-asparagine = dolichyl diphosphate + a glycoprotein with the oligosaccharide chain attached by N-glycosyl linkage to protein L-asparagine. UniProtKB P33767
Pathway: Protein modification; protein glycosylation. UniProtKB P33767
Subunit structure: Component of the oligosaccharyl transferase (OST) complex
By similarity. UniProtKB P33767
Subcellular location: Endoplasmic reticulum. Membrane; Single-pass type I membrane protein
By similarity Ref.3 UniProtKB P33767.
Domain: The cytoplasmic C-terminal domain contains a functional dilysine-retrieval motif, which is involved in the retrograde Golgi-to-ER transport of the protein
By similarity. UniProtKB P33767
Sequence similarities: Belongs to the DDOST 48 kDa subunit family.
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Product Notes
The wbp1 wbp1 (Catalog #AAA1243694) is a Recombinant Protein produced from E Coli or Yeast or Baculovirus or Mammalian Cell and is intended for research purposes only. The product is available for immediate purchase. The immunogen sequence is 20-437. The amino acid sequence is listed below: ARQTVLAVAD HDIGGYSTFL QSLTDRDFDV KTSYIKDESA KLFEYGERLY DNLILLSSQS KSLGPVFSPK SLLEFVQSGG NLFVVAGSQL PEGIRELGRQ LDMFLAERQS VVVDHFNHAE GSDDIILLDG ISENPYIISD ETRAAGPILY KGIGHYLGPN PQTQPILRGN PTSYIYNTKT EAEVSKNPWA AGTQLFLVSV LQSSTGERVG LSGSIDMLKD EYLSPQSPSF SKSNFLFARD LTNWVFQRKG VLQATNMTYG KVAEPLESRN ASCYRIKDEM IFSIDISLLE DGQQTPYVAD DVQLELIMLD PYYRVNLVPV PSDSQTSQHY EAVLVAPDHY GDFTFKIEYK RPGLTPIEEK STFTLRQFFH NEFPRFLPHA YPYYASCFSV LGAFLLFCGI WLLQKPAKPV VPSAKKQN. It is sometimes possible for the material contained within the vial of "Dolichyl-diphosphooligosaccharide--protein glycosyltransferase 48 kDa subunit (SPCC338.15), Recombinant Protein" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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