Vesicle Transport Through Interaction with t-SNAREs Homolog 1B Recombinant Protein | VTI1B recombinant protein
Recombinant Human Vesicle Transport Through Interaction with t-SNAREs Homolog 1B
Sterile Filtered colorless solution.
Introduction: VTI1B (v-SNARE) mediates vesicle transport pathways via interactions with t-SNAREs on the target membrane. These interactions are meant to facilitate aspects of the specificity of vesicle trafficking and to stimulate fusion of the lipid bilayers. VTI1B may be involved in increased secretion of cytokines connected with cellular senescence.
NCBI and Uniprot Product Information
Uniprot Description
VTI1B: V-SNARE that mediates vesicle transport pathways through interactions with t-SNAREs on the target membrane. These interactions are proposed to mediate aspects of the specificity of vesicle trafficking and to promote fusion of the lipid bilayers. May be concerned with increased secretion of cytokines associated with cellular senescence. Belongs to the VTI1 family. 2 isoforms of the human protein are produced by alternative splicing.
Protein type: Membrane protein, integral; Vesicle
Chromosomal Location of Human Ortholog: 14q24.1
Cellular Component: Golgi apparatus; endoplasmic reticulum membrane; intracellular membrane-bound organelle; late endosome membrane; lysosomal membrane; integral to membrane; SNARE complex; recycling endosome; synaptic vesicle; cell soma; perinuclear region of cytoplasm; cytoplasm; vesicle
Molecular Function: SNAP receptor activity; SNARE binding; chloride channel inhibitor activity
Biological Process: vesicle-mediated transport; cell proliferation; intra-Golgi vesicle-mediated transport; ER to Golgi vesicle-mediated transport; autophagic vacuole fusion; Golgi to vacuole transport; protein targeting to vacuole; vesicle fusion with Golgi apparatus; retrograde transport, endosome to Golgi; vesicle docking during exocytosis
Research Articles on VTI1B
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Product Notes
The VTI1B vti1b (Catalog #AAA144506) is a Recombinant Protein produced from E Coli and is intended for research purposes only. The product is available for immediate purchase. The amino acid sequence is listed below: MGSSHHH HHH SSGLVPRGSH MGSMAS SAAS SEHFEKLHEI FRGLHEDLQG VPERLLGTAG TEEKKKLIRD FDEKQQEANE TLAEMEEELR YAPLSFRNPM MSKLRNYRKD LAKLHREVRS TPLTATPGGR GDMKYGIYAV ENEHMNRLQS QRAMLLQGTE SLNRATQSIE RSHRIATETD QIGSEIIEEL GEQRDQLERT KSRLVNTSEN LSKSRKILRS MSRKVTTNKL L.. It is sometimes possible for the material contained within the vial of "Vesicle Transport Through Interaction with t-SNAREs Homolog 1B, Recombinant Protein" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
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