V-type proton ATPase subunit c (VMA3) Recombinant Protein | VMA3 recombinant protein

Recombinant Saccharomyces cerevisiae V-type proton ATPase subunit c (VMA3)

• Gene Names: VMA3; CLS7; CUP5; GEF2
• Purity: Greater or equal to 85% purity as determined by SDS-PAGE.
• Synonyms: V-type proton ATPase subunit c (VMA3); Recombinant Saccharomyces cerevisiae V-type proton ATPase subunit c (VMA3); Recombinant V-type proton ATPase subunit c (VMA3); V-type proton ATPase subunit c; V-ATPase subunit c; Guanine nucleotide exchange factor 2 V-ATPase 16 kDa proteolipid subunit 1 Vacuolar proton pump c subunit; VMA3 recombinant protein

• Host: E Coli or Yeast or Baculovirus or Mammalian Cell
• Purity/Purification: Greater or equal to 85% purity as determined by SDS-PAGE.
• Form/Format: Lyophilized or liquid (Format to be determined during the manufacturing process)
• Sequence Positions: 1-160
• Sequence: MTELCPVYAPFFGAIGCASAIIFTSLGAAYGTAKSGVGICATCVLRPDLLFKNIVPVIMAGIIAIYGLVVSVLVCYSLGQKQALYTGFIQLGAGLSVGLSGLAAGFAIGIVGDAGVRGSSQQPRLFVGMILILIFAEVLGLYGLIVALLLNSRATQDVVC
• Sequence Length: 160

• Species: Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
• Preparation and Storage: Store at -20 degree C. For extended storage, store at -20 or -80 degree C.

NCBI and Uniprot Product Information

• NCBI GI #: 398364261
• NCBI GeneID: 856686
• NCBI Accession #: NP_010887.3
• NCBI GenBank Nucleotide #: NM_001178842.3
• UniProt Accession #: P25515; D3DLM1
• Molecular Weight: 16,351 Da
• NCBI Official Full Name: Vma3p
• NCBI Official Symbol: VMA3
• NCBI Official Synonym Symbols: CLS7; CUP5; GEF2
• NCBI Protein Information: Vma3p
• UniProt Protein Name: V-type proton ATPase subunit c
• Protein Family: V-type proton ATPase
• UniProt Gene Name: VMA3
• UniProt Synonym Gene Names: CLS7; CUP5; GEF2; V-ATPase subunit c
• UniProt Entry Name: VATL1_YEAST

Uniprot Description

Function: Proton-conducting pore forming subunit of the membrane integral V0 complex of vacuolar ATPase. V-ATPase is responsible for acidifying a variety of intracellular compartments in eukaryotic cells. It is an electrogenic proton pump that generates a proton motive force of 180 mv, inside positive and acidic, in the vacuolar membrane vesicles.

Subunit structure: V-ATPase is a heteromultimeric enzyme composed of a peripheral catalytic V1 complex (components A to H) attached to an integral membrane V0 proton pore complex (components: a, c, c', c'', d and e). The proteolipid components c, c' and c'' are present as a hexameric ring that forms the proton-conducting pore.

Subcellular location: Vacuole membrane; Multi-pass membrane protein.

Miscellaneous: Present with 8450 molecules/cell in log phase SD medium.

Sequence similarities: Belongs to the V-ATPase proteolipid subunit family.