Spermatogenesis-defective protein 39 homolog Recombinant Protein | SPE39 recombinant protein
Recombinant Human Spermatogenesis-defective protein 39 homolog
Gene Names
VIPAS39; SPE39; VIPAR; SPE-39; VPS16B; hSPE-39; C14orf133
Reactivity
Human
Purity
Greater than 90% as determined by SDS-PAGE.
Synonyms
Spermatogenesis-defective protein 39 homolog; Recombinant Human Spermatogenesis-defective protein 39 homolog; VPS33B-interacting protein in apical-basolateral polarity regulatorVPS33B-interacting protein in polarity and apical restriction; SPE39 recombinant protein
Host
E Coli
Reactivity
Human
Purity/Purification
Greater than 90% as determined by SDS-PAGE.
Form/Format
20mM Tris-HCl based buffer, pH8.0
Sequence Positions
Full Length, 1-493aa
Tag Info
His-SUMO-tag
Preparation and Storage
Store at -20 degree C, for extended storage, conserve at -20 degree C or -80 degree C. Repeated freezing and thawing is not recommended. Store working aliquots at 4 degree C for up to one week.
Related Product Information for SPE39 recombinant protein
May play a role in vesicular trafficking during spermatogenesis. Plays a role in lysosomal trafficking, probably via association with the core HOPS complex in a discrete population of endosomes. May play a role in epithelial polarization through stabilization of apical mbrane protein content, possibly via the RAB11A-dependent apical recycling pathway. Also involved in direct or indirect transcriptional regulation of E-cadherin.
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
Molecular Weight
72.97kD
NCBI Official Full Name
spermatogenesis-defective protein 39 homolog isoform 1
NCBI Official Synonym Full Names
VPS33B interacting protein, apical-basolateral polarity regulator, spe-39 homolog
NCBI Official Symbol
VIPAS39
NCBI Official Synonym Symbols
SPE39; VIPAR; SPE-39; VPS16B; hSPE-39; C14orf133
NCBI Protein Information
spermatogenesis-defective protein 39 homolog
UniProt Protein Name
Spermatogenesis-defective protein 39 homolog
Protein Family
UniProt Gene Name
VIPAS39
UniProt Synonym Gene Names
C14orf133; SPE39; VIPAR; hSPE-39
NCBI Description
This gene encodes a protein involved in the sorting of lysosomal proteins. Mutations in this gene are associated with ARCS2 (arthrogryposis, renal dysfunction, and cholestasis-2). Alternative splicing results in multiple transcript variants.[provided by RefSeq, Jul 2010]
Uniprot Description
VIPAS39: a protein of unknown function. Two splice-variant isoforms have been described.
Protein type: Vesicle
Chromosomal Location of Human Ortholog: 14q24.3
Cellular Component: cytoplasm; early endosome; Golgi apparatus; late endosome; recycling endosome
Molecular Function: protein binding
Biological Process: collagen metabolic process; endosome to lysosome transport; intracellular protein transport; peptidyl-lysine hydroxylation
Disease: Arthrogryposis, Renal Dysfunction, And Cholestasis 2
Research Articles on SPE39
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Product Notes
The SPE39 vipas39 (Catalog #AAA9421461) is a Recombinant Protein produced from E Coli and is intended for research purposes only. The product is available for immediate purchase. The immunogen sequence is Full Length, 1-493aa. The Recombinant Human Spermatogenesis-defective protein 39 homolog reacts with Human and may cross-react with other species as described in the data sheet. It is sometimes possible for the material contained within the vial of "Spermatogenesis-defective protein 39 homolog, Recombinant Protein" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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