Probable ribonuclease VapC4 (vapC4) Recombinant Protein | vapC4 recombinant protein
Recombinant Mycobacterium tuberculosis Probable ribonuclease VapC4 (vapC4)
Purity
Greater or equal to 85% purity as determined by SDS-PAGE.
Synonyms
Probable ribonuclease VapC4 (vapC4); Recombinant Mycobacterium tuberculosis Probable ribonuclease VapC4 (vapC4); vapC4 recombinant protein
Host
E Coli or Yeast or Baculovirus or Mammalian Cell
Purity/Purification
Greater or equal to 85% purity as determined by SDS-PAGE.
Form/Format
Lyophilized or liquid (Format to be determined during the manufacturing process)
Sequence Positions
1-130, Full length protein
Sequence
MNVRRALADTSVFIGIEATRFDPDRFAGYEWGVSVVTLGELRLGVLQASGPEAAARRLSTYQLAQRFEPLGIDEAVSEAWALLVSKLRAAKLRVPINDSWIAATAVAHGIAILTQDNDYAAMPDVEVITI
Sequence Length
130
Species
Mycobacterium tuberculosis
Preparation and Storage
Store at -20 degrees C. For long-term storage, store at -20 degrees C or -80 degrees C. Store working aliquots at 4 degrees C for up to one week. Repeated freezing and thawing is not recommended.
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
Molecular Weight
14,112 Da
NCBI Official Full Name
ribonuclease VapC4
NCBI Official Symbol
vapC4
NCBI Protein Information
ribonuclease VapC4
UniProt Protein Name
Ribonuclease VapC4
Protein Family
UniProt Gene Name
vapC4
UniProt Synonym Gene Names
RNase VapC4
Uniprot Description
Toxic component of a type II toxin-antitoxin (TA) system. Probably exerts its toxic effect by binding to mRNA, inhibiting translation. Binds to, recognizes and cleaves ssRNA at ACGC and AC(A/U)GC sequences, usually between the G and C; cleavage is not very efficient, nor is cleavage required to inhibit protein synthesis. Upon expression in situ, in M.smegmatis or E.coli inhibits cell growth and colony formation; in at least E.coli also causes increased levels of cellular RNA. Its toxic effect is neutralized by coexpression with cognate antitoxin VapB4.
Research Articles on vapC4
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Product Notes
The vapC4 vapc4 (Catalog #AAA1196241) is a Recombinant Protein produced from E Coli or Yeast or Baculovirus or Mammalian Cell and is intended for research purposes only. The product is available for immediate purchase. The immunogen sequence is 1-130, Full length protein. The amino acid sequence is listed below: MNVRRALADT SVFIGIEATR FDPDRFAGYE WGVSVVTLGE LRLGVLQASG PEAAARRLST YQLAQRFEPL GIDEAVSEAW ALLVSKLRAA KLRVPINDSW IAATAVAHGI AILTQDNDYA AMPDVEVITI. It is sometimes possible for the material contained within the vial of "Probable ribonuclease VapC4 (vapC4), Recombinant Protein" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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