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Uncharacterized protein KIAA1530 (Kiaa1530) Recombinant Protein | Kiaa1530 recombinant protein

Recombinant Mouse Uncharacterized protein KIAA1530 (Kiaa1530)

Gene Names
Uvssa; Kiaa1530; mKIAA1530; 4933407H18Rik; D330017J19Rik
Purity
Greater or equal to 85% purity as determined by SDS-PAGE.
Synonyms
Uncharacterized protein KIAA1530 (Kiaa1530); Recombinant Mouse Uncharacterized protein KIAA1530 (Kiaa1530); Kiaa1530 recombinant protein
Ordering
For Research Use Only!
Host
E Coli or Yeast or Baculovirus or Mammalian Cell
Purity/Purification
Greater or equal to 85% purity as determined by SDS-PAGE.
Form/Format
Lyophilized or liquid (Format to be determined during the manufacturing process)
Sequence Positions
1-717, Full length protein
Sequence
MDQKLSQLIEELTTSGESQLNAQKMKELKKICKSSEEQLSHAYRLLITQLTQGHAEIRLSAFQIVDELFTRSHQFRMLLVSDFQEFLELTLGTDSDRPLPPPREAAQRLRQAAMQAVEGWNEKFGQAYKKLALGYHFLKHTKKVDFRDINVRTVAERKREEEKQKHLDKIHRESADRAKREMEEMYDEIECCLTEVENCFKLLVPLDFVPCPEDKFFGEASSMTEGYAPCPLSPDLATPRESGLSGPQDEEQPCCSKDLVASAYHVGSVVGLKALPQTAMKDSSRDEDEPSDPDDFLRSHGLGSHKYTLDVEVPSDGLKVQENEDNLAVLHAARDSLKLIQNKFLPTVCSWVQRFTRAGTYSAHLKQAIDLKMELELALKKYEELNIEPGRGQRSRTEALEDSEDEDQDFVEVPEKEGYEPRIPDHLRAEYGLEPKAPLKTLEKGTAVCKLQERTRMRREEEASDPTSAAAQMLRLQDCLSSPSPSSTRVLPGPEEAQKQAERARAPIVPFGVDLCYWGQEQLTAGKILKSDSQHRFWKPSEVEEEVDSAHVSEMLHSRHITFSGTFEPVQHKCRALRPNGRLCERQDRLKCPFHGKIIPRDDKGQPLNPEDRAREQRQQLQRQQAHPDWQDPEFLKDVEAATGVDLGSSRSSKKGKGKKKKHPNLTDLRERTNTARARLEKKVFAKAAVQRVVAAMNQMDQKKHEKFANQFNYALK
Sequence Length
717
Species
Mouse
Preparation and Storage
Store at -20 degrees C. For long-term storage, store at -20 degrees C or -80 degrees C. Store working aliquots at 4 degrees C for up to one week. Repeated freezing and thawing is not recommended.

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
Molecular Weight
81,759 Da
NCBI Official Full Name
UV-stimulated scaffold protein A
NCBI Official Synonym Full Names
UV stimulated scaffold protein A
NCBI Official Symbol
Uvssa
NCBI Official Synonym Symbols
Kiaa1530; mKIAA1530; 4933407H18Rik; D330017J19Rik
NCBI Protein Information
UV-stimulated scaffold protein A
UniProt Protein Name
UV-stimulated scaffold protein A
UniProt Gene Name
Uvssa
UniProt Synonym Gene Names
Kiaa1530

Uniprot Description

Factor involved in transcription-coupled nucleotide excision repair (TC-NER) in response to UV damage. TC-NER allows RNA polymerase II-blocking lesions to be rapidly removed from the transcribed strand of active genes. Acts by promoting stabilization of ERCC6 by recruiting deubiquitinating enzyme USP7 to TC-NER complexes, preventing UV-induced degradation of ERCC6 by the proteasome. Interacts with the elongating form of RNA polymerase II (RNA pol IIo) and facilitates its ubiquitination at UV damage sites, leading to promote RNA pol IIo backtracking to allow access to the nucleotide excision repair machinery. Not involved in processing oxidative damage ().

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Product Notes

The Kiaa1530 uvssa (Catalog #AAA1470431) is a Recombinant Protein produced from E Coli or Yeast or Baculovirus or Mammalian Cell and is intended for research purposes only. The product is available for immediate purchase. The immunogen sequence is 1-717, Full length protein. The amino acid sequence is listed below: MDQKLSQLIE ELTTSGESQL NAQKMKELKK ICKSSEEQLS HAYRLLITQL TQGHAEIRLS AFQIVDELFT RSHQFRMLLV SDFQEFLELT LGTDSDRPLP PPREAAQRLR QAAMQAVEGW NEKFGQAYKK LALGYHFLKH TKKVDFRDIN VRTVAERKRE EEKQKHLDKI HRESADRAKR EMEEMYDEIE CCLTEVENCF KLLVPLDFVP CPEDKFFGEA SSMTEGYAPC PLSPDLATPR ESGLSGPQDE EQPCCSKDLV ASAYHVGSVV GLKALPQTAM KDSSRDEDEP SDPDDFLRSH GLGSHKYTLD VEVPSDGLKV QENEDNLAVL HAARDSLKLI QNKFLPTVCS WVQRFTRAGT YSAHLKQAID LKMELELALK KYEELNIEPG RGQRSRTEAL EDSEDEDQDF VEVPEKEGYE PRIPDHLRAE YGLEPKAPLK TLEKGTAVCK LQERTRMRRE EEASDPTSAA AQMLRLQDCL SSPSPSSTRV LPGPEEAQKQ AERARAPIVP FGVDLCYWGQ EQLTAGKILK SDSQHRFWKP SEVEEEVDSA HVSEMLHSRH ITFSGTFEPV QHKCRALRPN GRLCERQDRL KCPFHGKIIP RDDKGQPLNP EDRAREQRQQ LQRQQAHPDW QDPEFLKDVE AATGVDLGSS RSSKKGKGKK KKHPNLTDLR ERTNTARARL EKKVFAKAAV QRVVAAMNQM DQKKHEKFAN QFNYALK. It is sometimes possible for the material contained within the vial of "Uncharacterized protein KIAA1530 (Kiaa1530), Recombinant Protein" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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