Uncharacterized protein KIAA1530 (Kiaa1530) Recombinant Protein | Kiaa1530 recombinant protein
Recombinant Mouse Uncharacterized protein KIAA1530 (Kiaa1530)
NCBI and Uniprot Product Information
Uniprot Description
Factor involved in transcription-coupled nucleotide excision repair (TC-NER) in response to UV damage. TC-NER allows RNA polymerase II-blocking lesions to be rapidly removed from the transcribed strand of active genes. Acts by promoting stabilization of ERCC6 by recruiting deubiquitinating enzyme USP7 to TC-NER complexes, preventing UV-induced degradation of ERCC6 by the proteasome. Interacts with the elongating form of RNA polymerase II (RNA pol IIo) and facilitates its ubiquitination at UV damage sites, leading to promote RNA pol IIo backtracking to allow access to the nucleotide excision repair machinery. Not involved in processing oxidative damage ().
Similar Products
Product Notes
The Kiaa1530 uvssa (Catalog #AAA1470431) is a Recombinant Protein produced from E Coli or Yeast or Baculovirus or Mammalian Cell and is intended for research purposes only. The product is available for immediate purchase. The immunogen sequence is 1-717, Full length protein. The amino acid sequence is listed below: MDQKLSQLIE ELTTSGESQL NAQKMKELKK ICKSSEEQLS HAYRLLITQL TQGHAEIRLS AFQIVDELFT RSHQFRMLLV SDFQEFLELT LGTDSDRPLP PPREAAQRLR QAAMQAVEGW NEKFGQAYKK LALGYHFLKH TKKVDFRDIN VRTVAERKRE EEKQKHLDKI HRESADRAKR EMEEMYDEIE CCLTEVENCF KLLVPLDFVP CPEDKFFGEA SSMTEGYAPC PLSPDLATPR ESGLSGPQDE EQPCCSKDLV ASAYHVGSVV GLKALPQTAM KDSSRDEDEP SDPDDFLRSH GLGSHKYTLD VEVPSDGLKV QENEDNLAVL HAARDSLKLI QNKFLPTVCS WVQRFTRAGT YSAHLKQAID LKMELELALK KYEELNIEPG RGQRSRTEAL EDSEDEDQDF VEVPEKEGYE PRIPDHLRAE YGLEPKAPLK TLEKGTAVCK LQERTRMRRE EEASDPTSAA AQMLRLQDCL SSPSPSSTRV LPGPEEAQKQ AERARAPIVP FGVDLCYWGQ EQLTAGKILK SDSQHRFWKP SEVEEEVDSA HVSEMLHSRH ITFSGTFEPV QHKCRALRPN GRLCERQDRL KCPFHGKIIP RDDKGQPLNP EDRAREQRQQ LQRQQAHPDW QDPEFLKDVE AATGVDLGSS RSSKKGKGKK KKHPNLTDLR ERTNTARARL EKKVFAKAAV QRVVAAMNQM DQKKHEKFAN QFNYALK. It is sometimes possible for the material contained within the vial of "Uncharacterized protein KIAA1530 (Kiaa1530), Recombinant Protein" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
If you are ready to order, navigate to Shopping Cart and get ready to checkout.