Typical Testing Data/Standard Curve (for reference only)
Rat Urotensin 2 ELISA Kit | UST2 elisa kit
Rat UST2 (Urotensin 2) ELISA Kit
Typical Testing Data/Standard Curve (for reference only)
Typical Testing Data/Standard Curve (for reference only)
Principle of the Assay: This ELISA kit uses Competitive-ELISA as the method. The microtiter plate provided in this kit has been pre-coated with UST2. During the reaction, UST2 in the sample or standard competes with a fixed amount of UST2 on the solid phase supporter for sites on the Biotinylated Detection Ab specific to UST2. Excess conjugate and unbound sample or standard are washed from the plate, and Avidin conjugated to Horseradish Peroxidase (HRP) is added to each microplate well and incubated. Then a TMB substrate solution is added to each well. The enzyme-substrate reaction is terminated by the addition of a sulphuric acid solution and the color change is measured spectrophotometrically at a wavelength of 450 nm +/- 2 nm. The concentration of UST2 in the samples is then determined by comparing the OD of the samples to the standard curve.
NCBI and Uniprot Product Information
NCBI Description
This gene encodes a mature peptide that is an active cyclic heptapeptide absolutely conserved from lamprey to human. The active peptide acts as a vasoconstrictor and is expressed only in brain tissue. Despite the gene family name similarity, this gene is not homologous to urocortin, a member of the sauvagine/corticotropin-releasing factor/urotensin I family. Most of the proprotein is cleaved to make the mature peptide. Transcript variants encoding different preproprotein isoforms have been described for this gene. [provided by RefSeq, Jul 2008]
Uniprot Description
UTS2: Highly potent vasoconstrictor. Belongs to the urotensin-2 family. 2 isoforms of the human protein are produced by alternative splicing.
Protein type: Secreted, signal peptide; Secreted
Chromosomal Location of Human Ortholog: 1p36
Cellular Component: cytosol; extracellular region; extracellular space
Molecular Function: hormone activity; receptor binding
Biological Process: elevation of cytosolic calcium ion concentration; muscle contraction; negative regulation of blood pressure; negative regulation of glomerular filtration; negative regulation of heart rate; negative regulation of insulin secretion; positive regulation of angiogenesis; positive regulation of blood pressure; positive regulation of cell differentiation; positive regulation of circadian sleep/wake cycle, REM sleep; positive regulation of collagen biosynthetic process; positive regulation of fibroblast proliferation; positive regulation of heart rate; positive regulation of synaptic transmission, cholinergic; positive regulation of vasodilation; regulation of blood pressure; response to drug; response to hypoxia; response to testosterone stimulus; synaptic transmission
Research Articles on UST2
Similar Products
Product Notes
The Rat UST2 uts2 (Catalog #AAA2533591) is an ELISA Kit and is intended for research purposes only. The product is available for immediate purchase. The AAA2533591 ELISA Kit recognizes Rat UST2. It is sometimes possible for the material contained within the vial of "Urotensin 2, ELISA Kit" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
If you are ready to order, navigate to Shopping Cart and get ready to checkout.
